Magnetic resonance imaging needle antennas

• US 7,551,953 B2
• Filed: 08/12/2003
• Issued: 06/23/2009
• Est. Priority Date: 04/15/1999
• Status: Expired due to Fees

• Current Assignee: SurgiVision Inc.
• Original Assignee: SurgiVision Inc.
• Inventors: McVeigh, Elliott R., Lardo, Albert C., Halperin, Henry R.
• Primary Examiner(s): Smith; Ruth S
• Application Number:
  US10/640,406
• Publication Number:
  US 20040199071A1
• Time in Patent Office: 2,142 Days
• Field of Search: 600/410, 600/411, 600/423, 600/424, 324/318, 324/322
• US Class Current: 600/411
• CPC Class Codes: G01R 33/285 Invasive instruments, e.g. catheters or biopsy needles, specially adapted for tracking, guiding or visualization by NMR
• CPC Class Codes: G01R 33/287 involving active visualization of interventional instruments, e.g. using active tracking RF coils or coils for intentionally creating magnetic field inhomogeneities
• CPC Class Codes: G01R 33/34053 Solenoid coils; Toroidal coils
• CPC Class Codes: G01R 33/34084 implantable coils or coils being geometrically adaptable to the sample, e.g. flexible coils or coils comprising mutually movable parts
• CPC Class Codes: H01Q 1/36 Structural form of radiating elements, e.g. cone, spiral, umbrella; Particular materials used therewithH01Q1/08, H01Q1/14 take precedence
• CPC Class Codes: H01Q 1/362 for broadside radiating helical antennas
• CPC Class Codes: H01Q 1/40 Radiating elements coated with or embedded in protective material
• CPC Class Codes: H01Q 1/44 using equipment having another main function to serve additionally as an antenna , e.g. means for giving an antenna an aesthetic aspectH01Q1/27 - H01Q1/34 take precedence
• CPC Class Codes: H01Q 11/08 Helical antennas

Abstract

The invention describes a system, method, and means for an MRI transseptal needle that can be visible on an MRI, can act as an antenna and receive MRI signals from surrounding subject matter to generate high-resolution images and can enable real-time active needle tracking during MRI guided transseptal puncture procedures.

Claims

1. An intracranial needle magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow needle at a distalmost end sharpened for penetrating central nervous system tissue, wherein the probe shaft is tubular and comprises an open lumen extending axially through the distalmost sharpened end, and the probe shaft further comprising a first conductor;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor define a magnetic resonance imaging antenna, and wherein the first conductor defines the hollow needle with the open lumen and has sufficient rigidity to penetrate the tissue.

2. The system of claim 1, wherein the antenna comprises a loopless antenna.

3. The system of claim 1, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

4. The system of claim 1, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

5. The system of claim 1, further comprising a balun circuit.

6. The system of claim 1, further comprising an interventional member in communication with the probe shaft.

7. A method for accessing an intracranial region of interest using magnetic resonance imaging, comprising:

providing an intracranial magnetic resonance imaging antenna system as set forth in claim 1;

employing the sharpened distalmost end of the probe shaft to penetrate central nervous system tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the intracranial region of interest in response to the signals received from the antenna.

8. The method of claim 7, further comprising ablating central nervous system tissue at the intracranial region of interest based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

9. The system of claim 1, wherein the lumen is a center lumen defined by a tubular body that extends between the proximal and distal ends of the probe shaft.

10. The system of claim 9, further comprising an obturator sized and configured to releasably reside in the lumen and extend through the sharpened end of the probe shaft.

11. The system of claim 1, wherein the probe shaft is a Nitinol tube having sufficient rigidity to define the sharpened distal end that is configured to penetrate the tissue.

12. The system of claim 11, further comprising a metallic coating on a distal portion of the Nitinol tube and a non-conductive coating on a proximal portion of the Nitinol tube.

13. The system of claim 1, wherein a distal end portion of the probe shaft has a curvature that curves away from a straight axial extension which extends from a location upstream of the sharpened end through the sharpened end.

14. The system of claim 12, wherein the metallic coating comprises platinum.

15. An endovascular magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow first conductor with a distalmost end sharpened for penetrating vascular tissue with the hollow first conductor having an open lumen extending axially through the distalmost sharpened end, wherein the probe shaft is tubular;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor define a magnetic resonance imaging antenna.

16. The system of claim 15, wherein the antenna comprises a loopless antenna.

17. The system of claim 15, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

18. The system of claim 15, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

19. The system of claim 15, further comprising a balun circuit.

20. The system of claim 15, further comprising an interventional tool in communication with the probe shaft.

21. A method for accessing an endovascular region of interest using magnetic resonance imaging, comprising:

providing an endovascular magnetic resonance imaging antenna system as set forth in claim 15;

employing the sharpened distalmost end of the probe shaft to penetrate vascular tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the endovascular region of interest in response to the signals received from the antenna.

22. The method of claim 21, further comprising ablating endovascular tissue at the region of interest based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

23. The system of claim 15, wherein the lumen is a center lumen defined by a tubular body that extends from a proximal end portion through the distalmost sharpened end of the probe shaft.

24. The system of claim 23, further comprising an obturator sized and configured to releasably reside in the lumen and extend through the sharpened end of the probe shaft.

25. The system of claim 15, wherein a distal end portion of the probe shaft has a curvature that curves away from a straight axial extension which extends from a location upstream of the sharpened end through the sharpened end.

26. A genitourinary magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow needle with an open lumen at a distalmost end sharpened for penetrating genitourinary tissue, wherein the probe shaft is tubular and the probe shaft further comprises a first conductor that extends to the sharpened distalmost end of the probe shaft and defines the hollow needle;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor define a magnetic resonance imaging antenna.

27. The system of claim 26, wherein the antenna comprises a loopless antenna.

28. The system of claim 26, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

29. The system of claim 26, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

30. The system of claim 29, wherein the connector is a snap-fit connector.

31. The system of claim 26, further comprising a balun circuit.

32. The system of claim 26, further comprising an interventional tool in communication with the probe shaft.

33. A method for accessing a genitourinary region of interest using magnetic resonance imaging, comprising:

providing a genitourinary magnetic resonance imaging antenna system as set forth in claim 26;

employing the sharpened distalmost end of the probe shaft to penetrate genitourinary tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the genitourinary region of interest in response to the signals received from the antenna.

34. The method of claim 33, further comprising ablating genitourinary tissue at the region of interest based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

35. The method of claim 33, wherein the genitourinary region of interest comprises bladder tissue.

36. The method of claim 33, wherein the genitourinary region of interest comprises urethral tissue.

37. The method of claim 33, wherein the genitourinary region of interest comprises prostatic tissue.

38. The method of claim 33, wherein the genitourinary region of interest comprises uterine tissue.

39. The method of claim 33, wherein the genitourinary region of interest comprises cervical tissue.

40. The method of claim 33, wherein the genitourinary region of interest comprises ovarian tissue.

41. The system of claim 26, wherein the lumen is a center lumen defined by a tubular body that extends from a proximal end portion through the distalmost sharpened end of the probe shaft.

42. The system of claim 41, further comprising an obturator sized and configured to releasably reside in the lumen and extend through the sharpened end of the probe shaft.

43. The system of claim 26, wherein a distal end portion of the probe shaft has a curvature that curves away from a straight axial extension which extends from a location upstream of the sharpened end through the sharpened end.

44. A nasogastric magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow needle with an axially extending open lumen at a distalmost end sharpened for penetrating nasogastric tissue, wherein the probe shaft is tubular and comprises a first conductor that defines the hollow needle;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor define a magnetic resonance imaging antenna.

45. The system of claim 44, wherein the antenna comprises a loopless antenna.

46. The system of claim 44, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

47. The system of claim 44, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

48. The system of claim 44, further comprising a balun circuit.

49. The system of claim 44, further comprising an interventional tool in communication with the probe shaft.

50. A method for accessing a nasogastric region of interest using magnetic resonance imaging, comprising:

providing a nasogastric magnetic resonance imaging antenna system as set forth in claim 44;

employing the sharpened distalmost end of the probe shaft to penetrate nasogastric tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the nasogastric region of interest in response to the signals received from the antenna.

51. The method of claim 50, further comprising ablating nasogastric tissue based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

52. An endotracheal magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow needle with an open lumen at a distalmost end sharpened for penetrating tracheal tissue, wherein the probe shaft is tubular and comprises an open lumen extending axially through the distalmost sharpened end and the probe shaft further comprising a first conductor, wherein the first conductor defines the hollow needle;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor define a magnetic resonance imaging antenna.

53. The system of claim 52, wherein the antenna comprises a loopless antenna.

54. The system of claim 52, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

55. The system of claim 52, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

56. The system of claim 52, further comprising a balun circuit.

57. The system of claim 52, further comprising an interventional tool in communication with the probe shaft.

58. A method for accessing an endotracheal region of interest using magnetic resonance imaging, comprising:

providing an endotracheal magnetic resonance imaging antenna system as set forth in claim 52;

employing the sharpened distalmost end of the probe shaft to penetrate tracheal tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the endotracheal region of interest in response to the signals received from the antenna.

59. The method of claim 58, further comprising ablating endotracheal tissue based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

60. An endobiliary magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow needle at a distalmost end sharpened for penetrating biliary tissue, wherein the probe shaft is tubular and comprises an open lumen extending axially through the distalmost sharpened end and the probe shaft further comprising a first conductor that defines the hollow needle with the open lumen;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor form a magnetic resonance imaging antenna.

61. The system of claim 60, wherein the antenna comprises a loopless antenna.

62. The system of claim 60, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

63. The system of claim 60, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

64. The system of claim 60, further comprising a balun circuit.

65. The system of claim 60, further comprising an interventional tool in communication with the probe shaft.

66. A method for accessing an endobiliary region of interest using magnetic resonance imaging, comprising:

providing an endobiliary magnetic resonance imaging antenna system as set forth in claim 60;

employing the sharpened distalmost end of the probe shaft to penetrate biliary tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the endobiliary region of interest in response to the signals received from the antenna.

67. The method of claim 66, further comprising ablating endobiliary tissue based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

68. A peritoneal magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow needle at a distalmost end sharpened for penetrating peritoneal tissue, wherein the probe shaft is tubular and comprises an open lumen extending axially through the distalmost sharpened end and the probe shaft further comprising a first conductor, wherein the first conductor defines the hollow needle;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor define a magnetic resonance imaging antenna.

69. The system of claim 68, wherein the antenna comprises a loopless antenna.

70. The system of claim 68, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

71. The system of claim 68, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

72. The system of claim 68, further comprising a balun circuit.

73. The system of claim 68, further comprising an interventional tool in communication with the probe shaft.

74. A method for accessing a peritoneal region of interest using magnetic resonance imaging, comprising:

providing a peritoneal magnetic resonance imaging antenna system as set forth in claim 68;

employing the sharpened distalmost end of the probe shaft to penetrate peritoneal tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the peritoneal region of interest in response to the signals received from the antenna.

75. The method of claim 74, further comprising ablating peritoneal tissue at the region of interest based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

76. An intradural magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow needle at a distalmost end sharpened for penetrating dural tissue, wherein the probe shaft is tubular and comprises an open lumen extending axially through the distalmost sharpened end, and the probe shaft further comprising a first conductor, wherein the first conductor defines the hollow needle;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor form a magnetic resonance imaging antenna.

77. The system of claim 76, wherein the antenna comprises a loopless antenna.

78. The system of claim 76, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

79. The system of claim 76, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

80. The system of claim 76, further comprising a balun circuit.

81. The system of claim 76, further comprising an interventional tool in communication with the probe shaft.

82. A method for accessing an intradural region of interest using magnetic resonance imaging, comprising:

providing an intradural magnetic resonance imaging antenna system as set forth in claim 76;

employing the sharpened distalmost end of the probe shaft to penetrate dural tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the intradural region of interest in response to the signals received from the antenna.

83. The method of claim 82, further comprising ablating dural tissue at the region of interest based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

84. An intraarticular magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow needle at a distalmost end sharpened for penetrating articular tissue, wherein the probe shaft is tubular and comprises an open lumen extending axially through the distalmost sharpened end, and the probe shaft further comprising a first conductor that defines the;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor define a magnetic resonance imaging antenna.

85. The system of claim 84, wherein the antenna comprises a loopless antenna.

86. The system of claim 84, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

87. The system of claim 84, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

88. The system of claim 84, further comprising a balun circuit.

89. The system of claim 84, further comprising an interventional tool in communication with the probe shaft.

90. A method for accessing an intraarticular region of interest using magnetic resonance imaging, comprising:

providing an intraarticular magnetic resonance imaging antenna system as set forth in claim 84;

employing the sharpened distalmost end of the probe shaft to penetrate articular tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the intraarticular region of interest in response to the signals received from the antenna.

91. The method of claim 90, further comprising ablating articular tissue at the region of interest based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

92. A nasopharyngeal magnetic resonance imaging antenna system, comprising:

a probe shaft having a distal end and a proximal end, the distal end of the probe shaft having a hollow needle at a distalmost end sharpened for penetrating nasopharyngeal tissue, wherein the probe shaft is tubular and comprises an open lumen extending axially through the distalmost sharpened end, and the probe shaft further comprising a first conductor that defines the hollow needle;

an insulator or dielectric covering the first conductor over at least the proximal portion of the probe shaft; and

a second conductor covering the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor define a magnetic resonance imaging antenna.

93. The system of claim 92, wherein the antenna comprises a loopless antenna.

94. The system of claim 92, further comprising an interface electrically coupled to the first conductor and the second conductor, the interface comprising tuning, matching, and decoupling circuitry.

95. The system of claim 92, wherein the proximal end of the probe shaft comprises a connector portion electrically coupled to the first conductor and the second conductor for connecting to a magnetic resonance scanner.

96. The system of claim 92, further comprising a balun circuit.

97. The system of claim 92, further comprising an interventional tool in communication with the probe shaft.

98. A method for accessing a nasopharyngeal region of interest using magnetic resonance imaging, comprising:

providing a nasopharyngeal magnetic resonance imaging antenna system as set forth in claim 92;

employing the sharpened distalmost end of the probe shaft to penetrate nasopharyngeal tissue;

receiving magnetic resonance imaging signals from the antenna;

tracking the progress of the antenna system in response to the signals received from the antenna; and

directing the antenna system toward the nasopharyngeal region of interest in response to the signals received from the antenna.

99. The method of claim 98, further comprising ablating nasopharyngeal tissue at the region of interest based on positional guidance of an interventional member cooperating with the probe shaft using the directing step.

100. A magnetic resonance imaging needle antenna system, comprising:

a tubular needle probe shaft having a length with opposing distal and proximal ends, the distal end of the probe shaft having a needle defined by a sufficiently rigid hollow first conductor with a distalmost end sharpened for penetrating target tissue and with the hollow first conductor having an open longitudinally extending lumen extending through the distalmost sharpened end;

an insulator or dielectric covering a major length of the first conductor at a location starting upstream of a distal end portion of the needle; and

a second conductor over the insulator or dielectric;

wherein the first conductor, the insulator or dielectric, and the second conductor define a magnetic resonance imaging antenna with the first conductor being a first pole and the second conductor being a second pole of a dipole loopless magnetic resonance receive antenna, and wherein the distal end portion of the needle defines an antenna whip of the antenna.

101. A magnetic resonance imaging needle antenna system according to claim 100, further comprising, a connector and an MRI scanner interface with matching and tuning circuitry adapted to cooperate with an MRI Scanner for MRI-guided interventional procedures, and wherein the distal end portion of the needle has a curvature that curves away from a straight axial extension which extends from a location upstream of the sharpened end through the sharpened end.

102. A magnetic resonance imaging needle antenna system according to claim 100, wherein the probe shaft is a Nitinol tube having sufficient rigidity to define the sharpened distalmost end that is configured to penetrate the tissue, and wherein the Nitinol tube comprises a metallic coating on at least a distal portion of the Nitinol tube and a non-conductive coating over the metallic portion and/or on a proximal portion of the Nitinol tube.

103. A magnetic resonance imaging needle antenna system according to claim 100, further comprising an interventional tool configured to cooperate with the probe shaft to thereby deliver a therapy to a patient.