Implant and methods thereof for treatment of ocular disorders

• US 7,563,241 B2
• Filed: 11/13/2006
• Issued: 07/21/2009
• Est. Priority Date: 04/07/2001
• Status: Expired due to Term

• Current Assignee: Glaukos Corporation
• Original Assignee: Glaukos Corporation
• Inventors: Niksch, Barbara A., Smedley, Gregory T., Tu, Hosheng, Haffner, David
• Primary Examiner(s): Deak; Leslie R
• Application Number:
  US11/598,542
• Publication Number:
  US 20070112292A1
• Time in Patent Office: 981 Days
• Field of Search: 604/8, 604/9, 604/264, 623/4.1, 623/6.12
• US Class Current: 604/8
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: A61M 27/00 Drainage appliance for wounds or the like , i.e. wound drains, implanted drains negative pressure wound therapy devices A61M1/90; implements for holding wound open A61B17/02 ; middle ear drainage A61F11/202

Abstract

Medical devices and methods for treating ocular disorders, such as glaucoma, are provided. One method involves inserting an implant on one side of an eye. The implant is advanced across the optic axis to the other side of the eye and implanted in contact with a choroid. In another method the implant is inserted through an incision in the eye into an anterior chamber of the eye. The implant is advanced from the incision and across the anterior chamber into eye tissue such that the implant is in contact with at least the choroid, or the implant drains aqueous humor from the anterior chamber toward the choroid.

Claims

1. A method for treating an ocular disorder, comprising:

forming an incision in an eye;

inserting an implant through the incision into an anterior chamber of the eye; and

advancing the implant within the anterior chamber from the incision, across an optic axis of the eye, and into eye tissue in direct contact with a choroid on the other side of the optic axis such that the implant drains aqueous humor from the anterior chamber toward the choroid.

2. The method of claim 1, wherein advancing the implant involves passing at least a portion of the implant over a guide member.

3. The method of claim 1, wherein the implant is positioned to allow fluid to enter the choroid.

4. The method of claim 1, wherein advancing the implant into eye tissue involves positioning at least a portion of the implant to contact the choroid.

5. The method of claim 4, wherein a distal end of the implant is positioned so as to be in contact with the choroid.

6. The method of claim 4, wherein positioning at least a portion of the implant to contact the choroid further comprises placing the portion of the implant to contact ciliary tissue of the eye.

7. The method of claim 6, wherein placing the portion of the implant to contact ciliary tissue of the eye comprises placing a distal portion of the implant to contact the ciliary tissue.

8. The method of claim 1, wherein the implant includes at least one lumen that provides a conduit from the anterior chamber to the choroid.

9. The method of claim 1 additionally comprising controlling flow through the implant.

10. The method of claim 9, wherein controlling flow involves providing a lumen having a sufficiently small cross-sectional area so as to limit flow of aqueous humor from the anterior chamber.

11. The method of claim 1, wherein forming an incision involves cutting into corneal tissue.

12. The method of claim 1, wherein a proximal end of the implant is positioned such that it communicates fluidicly with the anterior chamber.

13. A method for treating an ocular disorder, comprising:

inserting an implant on one side of an eye;

advancing the implant across an optic axis of the eye to the other side of the eye; and

implanting the implant in direct contact with a choroid.

14. The method of claim 13, wherein implanting the implant involves passing at least a portion of the implant over a guide member.

15. The method of claim 13, wherein the implant is positioned to allow fluid to enter the choroid.

16. The method of claim 13, wherein implanting the implant involves positioning a distal end of the implant to contact the choroid.

17. The method of claim 13, wherein the implant includes at least one lumen that provides a conduit from an anterior chamber of the eye to the choroid.

18. The method of claim 13 additionally comprising controlling flow through the implant.

19. The method of claim 18, wherein controlling flow involves providing a lumen having a sufficiently small cross-sectional area so as to limit flow of aqueous humor from an anterior chamber of the eye.

20. The method of claim 13, wherein advancing the implant involves advancing the implant across an anterior chamber of the eye.

21. The method of claim 13 additionally comprising draining aqueous humor through the implant.

22. The method of claim 13, wherein implanting the implant in direct contact with the choroid further comprises placing at least a portion of the implant in direct contact with ciliary tissue of the eye.

23. The method of claim 22, wherein placing the portion of the implant in direct contact with ciliary tissue of the eye comprises placing the distal portion of the implant in direct contact with the ciliary tissue.

24. The method of claim 13, wherein a proximal end of the implant is positioned such that it is disposed within an anterior chamber of the eye.

25. A method for treating an ocular disorder, comprising:

forming an incision in an eye on one side of an optic axis of an eye;

inserting an implant through the incision into an anterior chamber of the eye; and

advancing the implant from the incision on the one side of the optic axis, across the anterior chamber, and into eye tissue on the other side of the optic axis such that the implant is in direct contact with at least a choroid of the eye.

26. The method of claim 25 additionally comprising draining aqueous humor through the implant.

27. The method of claim 25, wherein forming an incision involves cutting into corneal tissue.

28. The method of claim 25, wherein advancing the implant involves passing at least a portion of the implant over a guide member.

29. The method of claim 25, wherein the implant is positioned to allow fluid to enter the choroid.

30. The method of claim 25, wherein advancing the implant into eye tissue involves positioning a distal end of the implant to contact the choroid.

31. The method of claim 25, wherein the implant includes at least one lumen that provides a conduit from the anterior chamber to the choroid.

32. The method of claim 25 additionally comprising controlling flow through the implant.

33. The method of claim 32, wherein controlling flow involves providing a lumen having a sufficiently small cross-sectional area so as to limit flow of aqueous humor from the anterior chamber.

34. The method of claim 25, wherein said advancing the implant further comprises placing at least a portion of the implant in direct contact with ciliary tissue of the eye.

35. The method of claim 34, wherein placing the portion of the implant in direct contact with ciliary tissue of the eye comprises placing a distal portion of the implant in direct contact with the ciliary tissue.

36. The method of claim 25, wherein a proximal end of the implant is positioned such that it is disposed within the anterior chamber.