Device for mixing and delivering pharmaceutical compositions
First Claim
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1. A method for delivering a pharmaceutical composition, the method comprising:
- a) independently ejecting at least two liquids, wherein at least one of the liquids is pharmacologically active, the at least two liquids being ejected from an electronically controlled jetting device toward and directly onto a solid mixing surface;
whereby, before being atomized, the at least two liquids become mixed while flowing on and channeling from the mixing surface out an exit orifice;
b) conveying the mixed liquid to an atomizing device;
c) atomizing the mixed liquid in the atomizing device; and
d) directing the atomized liquid to an end use destination;
wherein either;
i) the solid mixing surface comprises at least one of a solid mesh material or a solid porous material, and the mixing medium comprises a combination of the solid mixing surface and a liquid material in communication with the solid mixing surface, or p1 ii) the solid mixing surface comprises a combination of a liquid material and a solid porous material acting as the solid mixing surface.
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Abstract
A device and method for delivering a pharmaceutical composition. The device includes an electronically controllable jetting device in communication with a source of a pharmacologically active material and a solid or fluidic mixing medium for receiving the ejected pharmacologically active material and directing it toward an end use destination.
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Citations
49 Claims
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1. A method for delivering a pharmaceutical composition, the method comprising:
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a) independently ejecting at least two liquids, wherein at least one of the liquids is pharmacologically active, the at least two liquids being ejected from an electronically controlled jetting device toward and directly onto a solid mixing surface;
whereby, before being atomized, the at least two liquids become mixed while flowing on and channeling from the mixing surface out an exit orifice;b) conveying the mixed liquid to an atomizing device; c) atomizing the mixed liquid in the atomizing device; and d) directing the atomized liquid to an end use destination; wherein either; i) the solid mixing surface comprises at least one of a solid mesh material or a solid porous material, and the mixing medium comprises a combination of the solid mixing surface and a liquid material in communication with the solid mixing surface, or p1 ii) the solid mixing surface comprises a combination of a liquid material and a solid porous material acting as the solid mixing surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 48)
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12. A method for delivering a pharmaceutical composition, the method comprising:
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a) independently ejecting proportionate quantities of liquid materials from associated electronically controllable jetting devices toward and directly onto a solid mixing surface, at least one liquid material exhibiting pharmacological activity;
whereby, before being atomized, the ejected liquid materials become mixed while flowing on the solid mixing surface and channeling from the solid mixing surface out of an exit orifice;b) atomizing the mixed liquid materials in an atomizing device; and c) directing the atomized liquid materials to an end use destination; wherein either; i) the solid mixing surface comprises at least one of a solid mesh material or a solid porous material, and the mixing medium comprises a combination of the solid mixing surface and a liquid material in communication with the solid mixing surface, or ii) the solid mixing surface comprises a combination of a liquid material and a solid porous material acting as the solid mixing surface. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 49)
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20. A device for delivering a pharmaceutical composition, the device comprising:
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an electronically controllable jetting device in communication with at least two sources of liquids, at least one of the liquids being a pharmacologically active material; an atomizing device; and a solid mixing surface having an exit orifice, the solid mixing surface positioned to directly receive the liquids from the at least two sources, the liquids being independently ejected from the electronically controllable jetting device, and the solid mixing surface configured such that the at least two liquids become mixed, before being atomized, while flowing on the solid mixing surface and channeling from the solid mixing surface to the exit orifice, the exit orifice configured to convey the pharmacologically active material away from the solid mixing surface and to the atomizing device; wherein the solid mixing surface comprises a porous solid in fluid communication with a liquid material. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 47)
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32. A mixing dispensing device for use with a medical delivery system, the mixing dispensing device comprising:
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a housing; at least two reservoirs located in the housing, one of the reservoirs containing a pharmacologically active material and at least one other of the reservoirs containing an other material; an electronically controllable jetting device associated with the housing and in fluid communication with the at least two reservoirs, the electronically controllable jetting device independently ejecting the pharmacologically active material and the other material toward an end-use destination; a solid mixing surface interposed between the jetting device and the end-use destination, the solid mixing surface including a solid contact surface having an exit orifice, the solid contact surface positioned to directly receive the ejected pharmacologically active material and the other ejected material from the electronically controllable jetting device, whereby, before being atomized, the ejected materials become mixed while flowing on the solid contact surface and channeling from the solid contact surface out the exit orifice toward an atomizing device, the exit orifice being positioned to receive a flow of the ejected liquid from the solid contact surface and to direct the flow of the ejected liquid to the atomizing device; the atomizing device for atomizing the ejected fluid, the atomizing device positioned to direct a flow of atomized liquid to the end-use destination; and a memory element associated with the electronically controllable jetting device, the memory element configured to interactively communicate with a source external to the mixing dispensing device; wherein the solid mixing surface comprises a liquid in communication with the solid contact surface, and the solid contact surface comprises a porous material. - View Dependent Claims (33, 34, 35, 36, 37, 38, 39, 40)
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41. A cartridge for use with a medical dispensing system comprising;
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an electronically controllable jetting device in communication with at least two liquids, one of the at least two liquids being a pharmacologically active material; a mixing surface having an exit orifice, the mixing surface positioned to receive the at least two liquids independently ejected from the electronically controllable jetting device and wherein the mixing surface comprises at least one of a solid contact surface or a combination of a porous solid contact surface and a liquid material, whereby, before being atomized, the at least two liquids become mixed while flowing on the mixing surface and channeling from the mixing surface out an exit orifice opening toward a carrier stream source; the carrier stream source configured to supply a carrier stream toward an atomizing device, the carrier stream being adjacent the exit orifice of the mixing surface; and the atomizing device for atomizing the material, the atomizing device positioned to direct the flow of atomized material toward an end-use destination; wherein the exit orifice is configured to convey the pharmacologically active material away from the mixing surface into the carrier stream; and wherein the mixing surface comprises a detachable mixing surface module detachably mounted relative to the electronically controlled jetting device. - View Dependent Claims (42, 43, 44, 45, 46)
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Specification