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Labelled nucleotides

DC CAFC
  • US 7,566,537 B2
  • Filed: 12/13/2005
  • Issued: 07/28/2009
  • Est. Priority Date: 12/04/2001
  • Status: Expired due to Term
First Claim
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1. A method of labeling a nucleic acid molecule, the method comprising incorporating into the nucleic acid molecule a nucleotide or nucleoside molecule, wherein the nucleotide or nucleoside molecule has a base that is linked to a detectable label via a cleavable linker and the nucleotide or nucleoside molecule has a ribose or deoxyribose sugar moiety, wherein the ribose or deoxyribose sugar moiety comprises a protecting group attached via the 2′

  • or 3′

    oxygen atom, and said protecting group can be modified or removed to expose a 3′

    OH group and the protecting group comprises an azido group.

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