Methods and apparatus for obtaining low-dose imaging
First Claim
Patent Images
1. A method of imaging an object of interest positioned in an exposure area, the method comprising:
- obtaining projection data of the object by providing radiation from a radiation source to the exposure area and detecting, by at least one detector, at least some of the radiation exiting the object to form the projection data;
performing a first reconstruction of the projection data to form at least one bootstrap image;
obtaining first data based on information provided by the at least one bootstrap image including estimating an exit spectrum indicative of the energy spectrum of radiation exiting the object based, at least in part, on density information provided by the at least one bootstrap image; and
performing a second reconstruction of the projection data based, at least in part, on the first data to form at least one second image.
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Abstract
In one aspect, A method of imaging an object of interest positioned in an exposure area is provided. The method comprises obtaining projection data of the object by providing radiation to the exposure area and detecting at least some of the radiation exiting the object to form the projection data, performing a first reconstruction of the projection data to form at least one bootstrap image, obtaining first data based on information provided by the at least one bootstrap image, and performing a second reconstruction of the projection data based, at least in part, on the first data to form at least one second image.
52 Citations
18 Claims
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1. A method of imaging an object of interest positioned in an exposure area, the method comprising:
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obtaining projection data of the object by providing radiation from a radiation source to the exposure area and detecting, by at least one detector, at least some of the radiation exiting the object to form the projection data; performing a first reconstruction of the projection data to form at least one bootstrap image; obtaining first data based on information provided by the at least one bootstrap image including estimating an exit spectrum indicative of the energy spectrum of radiation exiting the object based, at least in part, on density information provided by the at least one bootstrap image; and performing a second reconstruction of the projection data based, at least in part, on the first data to form at least one second image. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of imaging an object of interest positioned in an exposure area, the method comprising:
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obtaining projection data of the object by providing radiation from a radiation source to the exposure area and detecting, by at least one detector, at least some of the radiation exiting the object to form the projection data; performing a first reconstruction of the projection data to form at least one bootstrap image; obtaining first data based on information provided by the at least one bootstrap image including obtaining information about locations of material within the object to facilitate estimating an amount of scattered radiation; performing a second reconstruction of the projection data based, at least in part, on the first data to form at least one second image; dividing an image of the object in the at least one bootstrap image into a plurality of regions; determining a depth of each of the plurality of regions with respect to a reference point related to a radiation source that provides the radiation to the exposure area; estimating an amount of scattered radiation resulting from each of the plurality of regions based on the possibility that radiation passing through the respective region would scatter at the associated depth; summing the estimates of scattered radiation to provide an estimate of the total scattered radiation; and modifying the projection data based, at least in part, on the estimate of the total scattered radiation.
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13. A method of imaging an object of interest positioned in an exposure area, the method comprising:
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obtaining projection data of the object by providing radiation from a radiation source to the exposure area and detecting, by at least one detectors, at least some of the radiation exiting the object to form the protection data; performing a first reconstruction of the projection data to form at least one bootstrap image; obtaining first data based on information provided by the at least one bootstrap image including obtaining boundary information indicative of a boundary of the object in the at least one bootstrap image, wherein obtaining the boundary information includes determining which pixels in the bootstrap image are outside of the boundary of the object, and wherein constraining the second reconstruction includes assigning zero-density values to pixels identified as being outside the boundary of the object; and performing a second reconstruction of the projection data based, at least in part, on the first data to form at least one second image including using the boundary information to constrain the second reconstruction.
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14. A method of imaging an object of interest positioned in an exposure area, the method comprising:
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obtaining projection data of the object by providing radiation from a radiation source to the exposure area and detecting, by at least one detector, at least some of the radiation exiting the object to form the projection data; arranging at least one density fiducial in the exposure area, prior to obtaining the projection data, such that at least some of the radiation encounters the at least one density fiducial; performing a first reconstruction of the projection data to form at least one bootstrap image; obtaining first data based on information provided by the at least one bootstrap image; and performing a second reconstruction of the projection data based, at least in part, on the first data to form at least one second image. - View Dependent Claims (15, 16, 17, 18)
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Specification