Method and apparatus for signal assessment including event rejection
First Claim
1. Apparatus adapted to evaluate the cardiac beats of a living subject, said apparatus comprising programmable medium having at least one fuzzy-based noise algorithm and at least one fuzzy-based morphology algorithm.
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Abstract
An improved method and apparatus for non-invasively assessing one or more physiologic parameters, such as for example those associated with the circulatory system of a living organism. In one exemplary embodiment, the invention evaluates cardiac events (e.g., beats) present within an ECG waveform to determine which beats should be retained and which rejected. This evaluation is conducted based on a hierarchical method, wherein the ECG noise and morphology, as well as various aspects of the Delta Z (change in thoracic impedance), are utilized to evaluate beats for retention/rejection. In one variant, fuzzy models are used in conducting the foregoing evaluations. Parameter median filtering is also optionally applied. The foregoing techniques increase the accuracy, stability and robustness of any systems (e.g., impedance cardiographic or otherwise) which make use of the events. Improved impedance cardiographic apparatus and methods of treatment are also disclosed.
70 Citations
45 Claims
- 1. Apparatus adapted to evaluate the cardiac beats of a living subject, said apparatus comprising programmable medium having at least one fuzzy-based noise algorithm and at least one fuzzy-based morphology algorithm.
- 4. Impedance cardiographic apparatus adapted to evaluate physiologic waveforms obtained from a living subject using programmable media adapted to contain a computer program thereon, said computer program adapted to store and evaluate criteria comprising (i) at least one ECG rejection criterion and (ii) at least one Delta Z rejection criterion.
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13. Cardiographic apparatus adapted to comprise media adapted to contain a computer program configured to store one or more criteria and evaluate the cardiac beats of a living subject using:
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an ECG rejection analysis; a Delta Z rejection analysis; and a median filtering analysis. - View Dependent Claims (14, 15, 16, 17)
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18. A method of evaluating the cardiac beats of a living subject, comprising:
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performing an ECG rejection analysis; performing a Delta Z rejection analysis; and performing a median filtering analysis. - View Dependent Claims (19, 20, 21)
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22. A method of assessing cardiac output within a living subject, comprising:
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disposing a plurality of electrodes relative to the thoracic cavity of said subject; passing an electrical current through at least a portion of said thoracic cavity; measuring at least one impedance waveform associated with said thoracic cavity using said current and at least one of said plurality of electrodes; measuring at least electrocardiographic waveform having a plurality of cardiac beats associated therewith; selectively rejecting at least one of said cardiac beats, said rejecting comprising evaluating a plurality of said beats using a multi-level hierarchical analysis algorithm; and determining cardiac output based at least in part on said impedance waveform and at least a portion of the non-rejected ones of said cardiac beats. - View Dependent Claims (23, 24, 25)
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26. A method of assessing cardiac output within a living subject, comprising:
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disposing a plurality of electrodes relative to the thoracic cavity of said subject; passing an electrical current through at least a portion of said thoracic cavity; measuring at least one impedance waveform associated with said thoracic cavity using said current and at least one of said plurality of electrodes; measuring at least electrocardiographic waveform having a plurality of events associated therewith; selectively rejecting at least one of said events, said rejecting comprising evaluating a plurality of cardiac beats based on (i) one or more ECG rejection criteria; and
(ii) one or more Delta Z rejection criteria; anddetermining cardiac output based at least in part on said impedance waveform and at least a portion of the non-rejected ones of said events. - View Dependent Claims (27, 28, 29, 30)
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31. A method of assessing a hemodynamic parameter within a living subject, comprising:
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disposing at least one electrode relative to said subject; measuring at least one cardiographic waveform from said subject using said at least one electrode, said waveform having a plurality of beats; processing said plurality of beats to identify first beats that should be rejected, and second beats that should not be rejected, said processing comprising evaluating plurality of beats with respect to at least one noise criterion and at least one morphology criterion; and assessing said hemodynamic parameter based at least in part on said second beats. - View Dependent Claims (32, 33)
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34. A method of assessing a hemodynamic parameter within a living subject, comprising:
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disposing at least one electrode relative to said subject; measuring at least one cardiographic waveform from said subject using said at least one electrode, said waveform having a plurality of beats; processing said plurality of beats to identify first beats that should be rejected, and second beats that should not be rejected, said processing comprising generating a Scale 1 wavelet filter; and assessing said hemodynamic parameter based at least in part on said second beats. - View Dependent Claims (35)
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36. A method of evaluating the cardiac beats of a living subject, comprising:
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performing a beat rejection analysis on a plurality of said cardiac beats, said beat rejection analysis comprising at least performing a morphology analysis; rejecting at least one of said beats as part of said rejection analysis; determining, based at least in part on said at least one rejected beat, a status of said rejection analysis, said act of determining a status comprising at least determining whether inputs to said morphology process are proper by at least evaluating the number of consecutive beat rejections including said at least one rejected beat; and when said determination indicates that more than a predetermined number of consecutive beats has occurred, utilizing an automatic ECG vector process to identify at least one proper input.
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37. A method of evaluating the cardiac beats of a living subject, comprising:
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providing a plurality of sources of said cardiac beats; performing a beat rejection analysis on a plurality of said cardiac beats derived from a first of said plurality of sources; rejecting at least one of said beats as part of said analysis; determining, based at least in part on said at least one rejected beat, the suitability of said first source for providing said cardiac beats; and selecting a second of said sources as an input to said beat rejection analysis when said act of determining indicates that said first source is not suitable; wherein said act of selecting comprises performing an auto-ECG vector analysis. - View Dependent Claims (38)
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39. A method of evaluating substantially periodic events within a time-variant waveform, comprising:
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providing a plurality of sources of said events; performing an event rejection analysis on a plurality of said events derived from a first of said plurality of sources; rejecting at least one of said events as part of said analysis; and determining, based at least in part on said at least one rejected event, the suitability of said first source for providing said events; wherein said events comprise Gaussian monopulses within a time-modulated ultrawideband communication system. - View Dependent Claims (40, 41)
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42. Apparatus adapted to evaluate the cardiac beats of a living subject, said apparatus comprising:
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a processor; a storage device in data communication with said processor; and at least one computer program resident in said storage device and adapted to run on said processor, said at least one program comprising; at least one fuzzy-based noise algorithm; and at least one fuzzy-based morphology algorithm. - View Dependent Claims (43, 44, 45)
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Specification