Delivery device

• US 7,571,723 B2
• Filed: 03/01/2007
• Issued: 08/11/2009
• Est. Priority Date: 09/04/1999
• Status: Expired due to Fees

• Current Assignee: Innovata Biomed Limited (Vectura Group Ltd.)
• Original Assignee: Innovata Biomed Limited (Vectura Group Ltd.)
• Inventors: Braithwaite, Philip
• Primary Examiner(s): Yu; Justine R
• Assistant Examiner(s): DIXON, ANNETTE FREDRICKA
• Application Number:
  US11/680,984
• Publication Number:
  US 20070163580A1
• Time in Patent Office: 894 Days
• Field of Search: 128/200.24, 128/203.12, 128/203.15, 128/203.19, 128/203.21, 221 92-133, 222129-1458, 222/153.02, 222/153.04
• US Class Current: 128/203.21
• CPC Class Codes: A61M 15/0003 with means for dispensing more than one drug
• CPC Class Codes: A61M 15/0045 using multiple prepacked dosages on a same carrier, e.g. blisters
• CPC Class Codes: A61M 15/0048 the dosages being arranged in a plane, e.g. on diskettes
• CPC Class Codes: A61M 15/0061 using pre-packed dosages having an insert inside
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61P 11/06 Antiasthmatics

Abstract

A delivery device, e.g. an inhaler, comprises a rotatable metering member adapted to dispense a measured amount of material, a material delivery passage and a material delivery orifice and at least one actuator member adapted to move the metering member from a material retaining position to a material dispensing position. In a magazine comprising a plurality of metering members, the actuator and metering members may operate in a radial direction. A plurality of rotatable magazines may be utilized in the delivery device. The delivery device may be used to deliver a single or a combination therapy.

Claims

1. A delivery device comprising a first rotatable magazine and a second rotatable magazine, each magazine being provided with a plurality of metering members adapted to dispense a measured amount of material, a material delivery passage and a material delivery orifice, and at least one push rod adapted to move a metering member from a material retaining position to a material dispensing position, wherein the device is provided with means for engaging the first magazine whilst disengaging the second magazine and which engaging means is moveable from an engaging to a disengaging position and vice-versa.

2. A delivery device according to claim 1 characterised in that the material is a medicament.

3. A delivery device according to claim 2 characterised in that the medicament metering member comprises a spool and a spool carrier wherein the void between the spool carrier is filled with medicament.

4. A delivery device according to claim 3 characterised in that the device is provided with a pair of magazines and said pair of magazines contain the same medicament.

5. A delivery device according to claim 3 characterised in that the device is provided with a pair of magazines and said pair of magazines contain different medicaments.

6. A delivery device according to claim 2 characterised in that the medicament delivery device is an inhaler.

7. A delivery device according to claim 1 characterised in that the material is a dry powder.

8. A delivery device according to claim 1 characterised in that the magazine is substantially circular.

9. A delivery device according to claim 1 characterised in that the engaging means comprises male and female interlocking members.

10. A delivery device according to claim 9 characterised in that the magazine is provided with a female member and a drive means is provided with a male member.

11. A delivery device according to claim 10 characterised in that a drive plate is provided with a male member and is adapted to engage with the drive means.

12. A delivery device according to claim 11 characterised in that the male member comprises a resilient protrusion which is resiliently biased towards a second magazine, but is constructed so as to be urged to engage with a female member of a first disc magazine, such that when the urging means is removed the male member is biased towards and engages with the second magazine.

13. A delivery device according to claim 12 characterised in that the actuator means comprises at least two radially acting push rod mechanisms which may operate together, independently or sequentially.

15. A dry powder inhaler according to claim 5 characterised in that the medicaments are fluticasone and salmeterol.

17. A method of administering a dry powder medicament using a delivery device according to claim 7.

18. A method according to claim 17 characterised in that a combination of medicaments are administered.

19. A method of treatment of a patient with a respiratory disorder comprising the administration of a therapeutically effective amount of a medicament using an inhaler according to claim 6.

14. A dry powder inhaler comprising a plurality of metering members adapted to dispense a measured amount of medicament and held in a first rotatable magazine and a second rotatable magazine, an inhalation passage and a mouthpiece, and at least one push rod adapted to move one of the plurality of metering members from a medicament retaining position to a medicament dispensing position, wherein the inhaler is provided with means for engaging the first magazine whilst disengaging the second magazine and which engaging means is moveable from an engaging to a disengaging position and vice-versa.

16. A dry powder inhaler according to claim 14 characterised in that the inhaler is provided with two push rods.