Adaptive windowing for cardiac waveform discrimination

• US 7,574,260 B2
• Filed: 04/28/2005
• Issued: 08/11/2009
• Est. Priority Date: 04/28/2005
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Meyer, Scott A., Dong, Yanting, Stalsberg, Kevin John, Bohn, Derek Daniel, Enrooth, Eric Keith
• Primary Examiner(s): Schaetzle; Kennedy J.
• Assistant Examiner(s): PATEL, NATASHA
• Application Number:
  US11/116,578
• Publication Number:
  US 20060247696A1
• Time in Patent Office: 1,566 Days
• Field of Search: 600/509, 600/515, 607/28, 128901-902
• US Class Current: 607/28
• CPC Class Codes: A61B 5/35 by template matching
• CPC Class Codes: A61B 5/366 Detecting abnormal QRS complex, e.g. widening
• CPC Class Codes: A61B 5/7217 of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation

Abstract

Cardiac devices and methods provide adaptation of detection windows used to determine a cardiac response to pacing. Adapting a detection window involves sensing a cardiac signal indicative of a particular type of cardiac pacing response, and detecting a feature of the sensed cardiac signal. The cardiac response detection window associated with the type of cardiac pacing response is preferentially adjusted based on the location of the detected cardiac feature. Preferential adjustment of the detection window may involve determining a direction of change between the detection window and the detected feature. The detection window may be adapted more aggressively in a more preferred direction and less aggressively in a less preferred direction.

Claims

1. A method of operating an implantable medical device, comprising:

defining at least one detection window;

sensing a cardiac signal;

detecting a feature of the sensed cardiac signal, the detected feature being disposed at a location relative to the detection window;

comparing the detected feature to the detection window;

determining a direction of change for the detection window based on comparison of the detected feature to the detection window; and

modifying the detection window to provide a modified detection window for use with a subsequent cardiac signal, comprising;

modifying the detection window using a first adjustment coefficient associated with a preferred direction in response to the direction of change corresponding to the preferred direction; and

modifying the detection window using a second adjustment coefficient associated with a second direction in response to the direction of change corresponding to the second direction, wherein modifying the detection window using the first adjustment coefficient modifies the detection window more aggressively than modifying the detection window using the second coefficient.

2. The method of claim 1, wherein modifying the detection window comprises increasing or decreasing one or both of an amplitude coordinate and a time coordinate of the detection window toward the detected feature, wherein the coordinate is modified by a greater amount if the first coefficient is used and is modified by a lesser amount if the second coefficient is used.

3. The method of claim 1, wherein modifying the detection window includes comparing the direction of change to the preferred direction and selecting the first adjustment coefficient if the direction of change corresponds to the preferred direction.

4. The method of claim 1, wherein modifying the detection window comprises advancing or retarding the detection window in time.

5. The method of claim 1, wherein comparing the detected feature to the detection window comprises comparing an amplitude coordinate of the detected feature an amplitude coordinate of the detection window.

6. The method of claim 1, wherein:

comparing the detected feature to the detection window comprises comparing a time coordinate of the detected feature and a time coordinate of the detection window and

modifying the detection window comprises using the first adjustment coefficient to modify the detection window if the coordinate of the detected feature is before the coordinate of the detection window, and using the second adjustment coefficient to modify the detection window if the coordinate of the detected feature is after the coordinate of the detection window.

7. The method of claim 1, wherein modifying the detection window includes adjusting a location of the detection window.

8. The method of claim 1, wherein modifying the detection window includes adjusting a size, shape, area, or boundary of the detection window.

9. The method of claim 1, wherein:

defining a detection window includes defining at least one detection window limit; and

modifying the detection window further comprises modifying the detection window based on the at least one detection window limit.

10. The method of claim 1, wherein the detection window includes a capture detection window, a fusion detection window, an intrinsic detection window, or a noise detection window.

11. The method of claim 1, wherein the at least one detection window comprises a plurality of detection windows and the plurality of detection windows are respectively associated with preferred directions of change.

12. The method of claim 1, wherein the at least one detection window comprises two or more of a capture detection window, a fusion detection window, an intrinsic detection window, and a noise detection window.

13. The method of claim 1, wherein:

defining the at least one detection window comprises defining a detection window associated with a positive peak and a detection window associated with a negative peak; and

determining the direction of change for the at least one detection window comprises determining a direction of change for the positive peak detection window and determining a direction of change for the negative peak detection window.

14. The method of claim 13, wherein modifying the detection window comprises:

modifying the positive peak detection window using an adjustment coefficient associated with a preferred direction of change for the positive peak detection window; and

modifying the negative peak detection window using a negative peak adjustment coefficient associated with a preferred direction of change for the negative peak detection window.

15. A system, comprising:

a sensing system configured to sense a cardiac signal following a pacing pulse delivered to a heart; and

a processor coupled to the sensing system, the processor configured to (a) provide at least one detection window (b) detect a feature of the cardiac signal, the detected feature being disposed at a location relative to the detection window, (c) compare the detected feature to the detection window, (d) determine a direction of change for the detection window based on a comparison of the detected feature to the detection window, and (e) modify the detection window using a first adjustment coefficient associated with a preferred direction of change in response to the direction of change corresponding to the preferred direction and modify the detection window using a second adjustment coefficient associated with a second direction in response to the direction of change corresponding to the second direction, wherein the first coefficient provides a more aggressive modification of the detection window than the second coefficient.

16. The system of claim 15, wherein the processor is configured to compare the direction of change with the preferred direction.

17. The system of claim 15, wherein the processor is configured to modify the detection window by adjusting it toward the detected feature by an amount that depends on whether the first or second adjustment coefficient is used for the modification.

18. The system of claim 15, wherein the processor is configured to compare a coordinate of the detected feature to a coordinate of the detection window.

19. The system of claim 18, wherein the coordinate of the detected feature and the coordinate of the detection window are time coordinates, and wherein the processor utilizes the first adjustment coefficient for a modification that advances the detection window in time and the second adjustment coefficient different from the first adjustment coefficient for a modification that retards the detection window in time.

20. The system of claim 15, wherein the processor is further configured to provide at least one detection window limit, and wherein the processor is configured to modify the detection window based on the detection window limit.

21. The system of claim 15, wherein the processor is configured to associate the cardiac signal with a type of cardiac response to the pacing pulse based on the comparison of the detected feature to the detection window, and wherein the type of cardiac response includes a capture response, a fusion response, an intrinsic response, or a noise response.

22. A system for adjusting a detection window used to detect a type of cardiac response, comprising:

a detector configured to detect a feature of a cardiac signal;

means for comparing the detected feature to a detection window, the detected feature being disposed at a location relative to the detection window;

means for determining direction of change based on comparison of the detected feature to the detection window; and

means for modifying the detection window to provide a modified detection window for use with a subsequent cardiac signal, comprising;

means for modifying the detection window using the first adjustment coefficient associated with a preferred direction in response to the direction of change corresponding to the preferred direction; and

means for modifying the detection window using a second adjustment coefficient associated with a second direction in response to the direction of change corresponding to the second direction, wherein the first coefficient provides a more aggressive modification of the detection window than the second coefficient.

23. The system of claim 22, wherein the modifying means modifies the detection window based on a detection window limit.

24. The system of claim 22, wherein the comparing means associates the cardiac signal with a type of cardiac response based on the comparison of the detected feature to the detection window, and wherein the type of cardiac response includes a capture response, a fusion response, an intrinsic response, or a noise response.