Heated mechanical detachment for delivery of therapeutic devices
First Claim
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1. An system for the endoluminal delivery of a therapeutic device, comprising:
- a therapeutic device having a proximal end portion and a distal end portion;
a pusher element sized and shaped for intraluminal delivery, said pusher element having a distal end portion;
a decoupling assembly attached to said distal end portion of said pusher, said decoupling assembly including an energy-responsive element;
said decoupling assembly including a retention element having an offset orientation at which the retention element retains said therapeutic device, said retention element also having a generally collapsed orientation;
said decoupling assembly further including a thermally-responsive element having an expanded configuration that maintains said retention element in said offset orientation and having an altered configuration that does not maintain said retention element in said offset orientation;
said thermally-responsive element, retention element and energy-responsive element are designed, sized and shaped relative to each other such that said thermally-responsive element assumes said altered configuration when energy is transmitted to said energy-responsive element and said retention element moves to its said collapsed orientation and no longer retains said therapeutic device; and
a membrane encapsulating said thermally-responsive element.
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Abstract
The disclosure describes apparatuses and methods for the luminal delivery of therapeutic devices. The apparatus includes a decoupling assembly comprising a retention element, a energy-responsive element and a thermally sensitive element. The application of heat to the thermally sensitive element alters its configuration such that it no longer maintains the retention element in engagement with the therapeutic device, releasing the therapeutic device.
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Citations
30 Claims
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1. An system for the endoluminal delivery of a therapeutic device, comprising:
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a therapeutic device having a proximal end portion and a distal end portion; a pusher element sized and shaped for intraluminal delivery, said pusher element having a distal end portion; a decoupling assembly attached to said distal end portion of said pusher, said decoupling assembly including an energy-responsive element; said decoupling assembly including a retention element having an offset orientation at which the retention element retains said therapeutic device, said retention element also having a generally collapsed orientation; said decoupling assembly further including a thermally-responsive element having an expanded configuration that maintains said retention element in said offset orientation and having an altered configuration that does not maintain said retention element in said offset orientation; said thermally-responsive element, retention element and energy-responsive element are designed, sized and shaped relative to each other such that said thermally-responsive element assumes said altered configuration when energy is transmitted to said energy-responsive element and said retention element moves to its said collapsed orientation and no longer retains said therapeutic device; and a membrane encapsulating said thermally-responsive element. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A decoupling assembly for engagement and release of a therapeutic device, comprising:
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an energy-responsive element; a retention element having an offset orientation that maintains a therapeutic device and has a generally collapsed orientation; a thermally-responsive element having an expanded configuration that maintains said retention element in said offset orientation and having an altered configuration that does not maintain said retention element in said offset orientation; said thermally-responsive element, retention element and energy-responsive element are sized and shaped relative to each other such that said thermally-responsive element assumes said altered configuration when energy is transmitted to said energy-responsive element and said retention element moves to its said collapsed orientation; and said thermally-responsive element is formed from a material selected from the group consisting of low temperature solder, hot melt adhesives, waxes and low melting point metals. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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19. An system for the endoluminal delivery of a therapeutic device, comprising:
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an embolic coil therapeutic device having a proximal end portion and a distal end portion; a pusher element sized and shaped for intraluminal delivery, said pusher element having a distal end portion; a decoupling assembly attached to said distal end portion of said pusher, said decoupling assembly including an energy-responsive element; said decoupling assembly including a retention element having an offset orientation at which the retention element retains said therapeutic device, said retention element also having a generally collapsed orientation; said decoupling assembly further including a thermally-responsive element having an expanded configuration that maintains said retention element in said offset orientation and having an altered configuration that does not maintain said retention element in said offset orientation; said thermally-responsive element, retention element and energy-responsive element are designed, sized and shaped relative to each other such that said thermally-responsive element assumes said altered configuration when energy is transmitted to said energy-responsive element and said retention element moves to its said collapsed orientation and no longer retains said therapeutic device; and said thermally-responsive element is formed from a material selected from the group consisting of low temperature solder, hot melt adhesives, waxes and low melting point metals. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26)
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27. A decoupling assembly for engagement and release of a therapeutic device, comprising:
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an energy-responsive element; a retention element having an offset orientation that maintains a therapeutic device and has a generally collapsed orientation; a thermally-responsive element having an expanded configuration that maintains said retention element in said offset orientation and having an altered configuration that does not maintain said retention element in said offset orientation; said thermally-responsive element, retention element and energy-responsive element are sized and shaped relative to each other such that said thermally-responsive element assumes said altered configuration when energy is transmitted to said energy-responsive element and said retention element moves to its said collapsed orientation; and a material encapsulating said thermally-responsive element. - View Dependent Claims (28, 29, 30)
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Specification