Thermoelectric temperature control for extracorporeal blood circuit
First Claim
1. A device for directly controlling temperature of blood flowing through an extracorporeal blood circuit, comprising:
- a thermoelectric module for coupling to a supply voltage to generate a temperature difference; and
a heat exchanger cassette comprising a core and first and second laminar flow guides, wherein the core is in thermal contact with the thermoelectric module and has a plurality of tubes for carrying parallel channels of the blood, wherein the first and second laminar flow guides provide an inlet and an outlet for coupling to the extracorporeal blood circuit, wherein the tubes are grouped into respective multi-tube cells, wherein all the tubes in any particular multi-tube cell carry the blood in parallel and in the same direction, wherein the first and second laminar flow guides include respective intermediate chambers for receiving respective ends of the tubes in order to connect the multi-tube cells in series between the inlet and the outlet, wherein each intermediate chamber carries a combined flow from one multi-tube cell to a following multi-tube cell, wherein the intermediate chambers each include a radially-curved outside wall for reversing the direction of flow from one multi-tube cell to the next while maintaining a substantially laminar flow, wherein a thermal transfer matrix encapsulates the tubes and provides a thermally conductive path between the tubes and the thermoelectric module, and wherein the thermal transfer matrix is an electrical insulator.
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Accused Products
Abstract
A waterless blood heater/cooler device directly controlling temperature of blood flowing through an extracorporeal blood circuit. A thermoelectric module is coupled to a supply voltage to generate a temperature difference. A heat exchanger cassette comprising a core and first and second laminar flow guides is in thermal contact (directly or indirectly) with the thermoelectric module. The cassette has a plurality of tubes for carrying parallel channels of the blood. The first and second laminar flow guides provide an inlet and an outlet for coupling to the extracorporeal blood circuit and respective intermediate chambers for receiving respective ends of the tubes in order to guide the blood to and from respective tubes in a substantially laminar flow.
70 Citations
18 Claims
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1. A device for directly controlling temperature of blood flowing through an extracorporeal blood circuit, comprising:
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a thermoelectric module for coupling to a supply voltage to generate a temperature difference; and a heat exchanger cassette comprising a core and first and second laminar flow guides, wherein the core is in thermal contact with the thermoelectric module and has a plurality of tubes for carrying parallel channels of the blood, wherein the first and second laminar flow guides provide an inlet and an outlet for coupling to the extracorporeal blood circuit, wherein the tubes are grouped into respective multi-tube cells, wherein all the tubes in any particular multi-tube cell carry the blood in parallel and in the same direction, wherein the first and second laminar flow guides include respective intermediate chambers for receiving respective ends of the tubes in order to connect the multi-tube cells in series between the inlet and the outlet, wherein each intermediate chamber carries a combined flow from one multi-tube cell to a following multi-tube cell, wherein the intermediate chambers each include a radially-curved outside wall for reversing the direction of flow from one multi-tube cell to the next while maintaining a substantially laminar flow, wherein a thermal transfer matrix encapsulates the tubes and provides a thermally conductive path between the tubes and the thermoelectric module, and wherein the thermal transfer matrix is an electrical insulator. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A blood perfusion system for coupling to a patient during cardiac surgery, comprising:
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an inlet line carrying blood removed from the patient; an return line carrying blood from the perfusion system back to the patient; a pump for circulating blood from the inlet line to the return line; an oxygenator coupled between the inlet line and the return line for oxygenating the blood; and a heater/cooler coupled between the inlet line and the return line in series with the oxygenator, the heater/cooler comprising; a thermoelectric module for coupling to a supply voltage to generate a temperature difference; and a heat exchanger cassette comprising a core and first and second laminar flow guides, wherein the core is in thermal contact with the thermoelectric module and has a plurality of tubes for carrying parallel channels of the blood, wherein the first and second laminar flow guides provide an inlet and an outlet for coupling to the extracorporeal blood circuit, wherein the tubes are grouped into respective multi-tube cells, wherein all the tubes in any particular multi-tube cell carry the blood in parallel and in the same direction, wherein the first and second laminar flow guides include respective intermediate chambers for receiving respective ends of the tubes in order connect the multi-tube cells in series between the inlet and the outlet, wherein each intermediate chamber carries a combined flow from one multi-tube cell to a following multi-tube cell, wherein the intermediate chambers each include a radially-curved outside wall for reversing the direction of flow from one multi-tube cell to the next while maintaining a substantially laminar flow, wherein a thermal transfer matrix encapsulates the tubes and provides a thermally conductive path between the tubes and the thermoelectric module, and wherein the thermal transfer matrix is an electrical insulator.
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17. A device for directly controlling temperature of blood flowing through an extracorporeal blood circuit, comprising:
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a thermoelectric module for coupling to a supply voltage to generate a temperature difference; and a heat exchanger cassette comprising a core and first and second laminar flow guides at first and second ends of the core, wherein the core has first and second sealing collars at the first and second ends for receiving the first and second laminar flow guides, respectively, wherein the core is in thermal contact with the thermoelectric module and has a plurality of spaced tubes for carrying parallel channels of the blood, wherein the first and second laminar flow guides provide an inlet and an outlet for coupling to the extracorporeal blood circuit, wherein the tubes are grouped into respective multi-tube cells, wherein all the tubes in any particular multi-tube cell carry the blood in parallel and in the same direction, wherein the first and second laminar flow guides include respective intermediate chambers for receiving respective ends of the tubes in order to connect the multi-tube cells in series between the inlet and the outlet, wherein each intermediate chamber carries a combined flow from one multi-tube cell to a following multi-tube cell, wherein the intermediate chambers each include a radially-curved outside wall for reversing the direction of flow from one multi-tube cell to the next while maintaining a substantially laminar flow, wherein a thermal transfer matrix fills the space between the tubes and encapsulates the tubes to provide a thermally conductive path between the tubes and the thermoelectric module, and wherein the thermal transfer matrix is an electrical insulator. - View Dependent Claims (18)
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Specification