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Pharmaceutical formulation for contraception and hormone-replacement therapy

  • US 7,589,082 B2
  • Filed: 06/10/2004
  • Issued: 09/15/2009
  • Est. Priority Date: 06/13/2003
  • Status: Expired due to Fees
First Claim
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1. A method for effecting simultaneous contraception and hormone replacement therapy in a female mammal comprising administering to said mammal a pharmaceutical formulation comprising particles of 17-β

  • -estradiol and cholesterol in about a 1;

    1 molar ratio, and particles of progesterone;

    wherein the weight ratio of 17-β

    -estradiol to progesterone is about 1;

    40, and wherein the 17-β

    -estradiol is about 50-60% amorphous and about 40-50% crystalline.

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