Methods for ventricular pacing

• US 7,590,446 B1
• Filed: 11/10/2004
• Issued: 09/15/2009
• Est. Priority Date: 11/05/2003
• Status: Expired due to Fees

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Min, Xiaoyi, Bornzin, Gene A.
• Primary Examiner(s): Evanisko; George R
• Assistant Examiner(s): ALTER, ALYSSA MARGO
• Application Number:
  US10/986,273
• Time in Patent Office: 1,770 Days
• Field of Search: 607/9, 607/17, 607/25
• US Class Current: 607/9
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

An exemplary method includes determining an atrial to ventricular activation time for a right ventricle; determining an atrial to ventricular activation time for a left ventricle; and determining a pacing sequence that paces the right ventricle prior to activation of the left ventricle if the time for the right ventricle exceeds the time for the left ventricle or that paces the left ventricle prior to activation of the right ventricle if the time for the left ventricle exceeds the time for the right ventricle, wherein, in the pacing sequence, pacing of the prior, paced ventricle occurs at a time based at least in part on a difference between the time for the right ventricle and the time for the left ventricle and an atrio-ventricular delay limit. Various other exemplary methods, devices and/or systems are also disclosed.

Claims

1. A method comprising:

detecting intrinsic ventricular activity of a right ventricle;

detecting intrinsic ventricular activity of a left ventricle;

computing a time difference between the intrinsic ventricular activity of the right ventricle and the intrinsic ventricular activity of the left ventricle;

delivering a pacing pulse to one of the right and left ventricles and measuring corresponding intrinsic activity of the other of the right and left ventricles, and computing a second time difference between the pacing pulse and the corresponding intrinsic activity;

determining a pacing interval for a v-v delay based at least in part on the time difference between the ventricular activity of the right ventricle and the ventricular activity of the left ventricle, wherein the pacing interval for the v-v delay is set as a function of the time difference between the ventricular activity of the right ventricle and the ventricular activity of the left ventricle and as a function of the second time difference between the pacing pulse and the corresponding intrinsic activity; and

delivering one or more pacing pulses to at least one of the right and left ventricles based on the pacing interval.

2. The method of claim 1 wherein:

detecting ventricular activity in a right ventricle comprises detecting electrical activity.

3. The method of claim 1 and further comprising:

determining a pacing sequence that paces the right ventricle first if the time for the right ventricle exceeds the time for the left ventricle or that paces the left ventricle first if the time for the left ventricle exceeds the time for the right ventricle.

4. The method of claim 3, wherein the determining a pacing sequence relies at least in part on a predetermined atrio-ventricular delay.

5. The method of claim 1, wherein computing a time difference comprises determining an absolute value of the difference between the ventricular activity time for the right ventricle and the ventricular activity time for the left ventricle.

6. The method of claim 3, wherein determining the pacing sequence comprises pacing the latter activated ventricle to achieve a predetermined atrio-ventricular delay.

7. The method of claim 1, wherein detecting ventricular activity for the right and left ventricles comprises using a single sense amplifier.

8. An implantable device comprising:

means for detecting intrinsic ventricular activity of a right ventricle;

means for detecting intrinsic ventricular activity of a left ventricle;

means for computing a time difference between the intrinsic ventricular activity of the right ventricle and the intrinsic ventricular activity of the left ventricle;

means for delivering a pacing pulse to one of the right and left ventricles and means for measuring corresponding intrinsic activity of the other of the right and left ventricles, and means for computing a second time difference between the pacing pulse and the pulse and the corresponding intrinsic activity; and

means for determining a pacing interval for a v-v delay based at least in part on the time difference between the ventricular activity of the right ventricle and the ventricular activity of the left ventricle comprising means for setting the pacing interval for the v-v delay as a function of the time difference between the ventricular activity of the right ventricle and the ventricular activity of the left ventricle and as a function of the second time difference between the pacing pulse and the corresponding intrinsic activity.

9. The implantable device of claim 8 and further comprising:

means for determining a pacing sequence that paces the right ventricle first if the time for the right ventricle exceeds the time for the left ventricle or that paces the left ventricle first if the time for the left ventricle exceeds the time for the right ventricle.

10. The implantable device of claim 9, wherein the means for determining a pacing sequence comprises means for relying on a predetermined atrio-ventricular delay.

11. The implantable device of claim 9, wherein the means for determining the pacing sequence comprises means for pacing the latter activated ventricle to achieve a predetermined atrio-ventricular delay.

12. The implantable device of claim 8, wherein the means for computing a time difference comprises means for determining an absolute value of the difference between the ventricular activity for the right ventricle and the ventricular activity for the left ventricle.

13. The implantable device of claim 8, wherein the means for detecting ventricular activity for the right and left ventricles comprises a single sense amplifier.

14. An implantable device comprising:

a power supply;

at least one lead comprising one or more electrodes capable of being positioned within a patient'"'"'s body to sense activity of a right ventricle and of a left ventricle; and

a processor that is operative to receive activity signals from the at least one lead to detect intrinsic ventricular activity of the right ventricle and intrinsic ventricular activity of the left ventricle, to compute a time difference between the ventricular activity of the right and left ventricles, to deliver a pacing pulse to one of the right and left ventricles and measure corresponding intrinsic activity of the other of the right and left ventricles, compute a second time difference between the pacing pulse and the corresponding intrinsic activity, and to determine a pacing interval for a v-v delay based at least in part on the time difference, wherein the pacing interval for the v-v delay is set as a function of the time difference between the ventricular activity of the right ventricle and the ventricular activity of the left ventricle and as a function of the second time difference between the pacing pulse and the corresponding intrinsic activity.