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Implantable devices for accelerated healing

  • US 7,591,841 B2
  • Filed: 12/16/2005
  • Issued: 09/22/2009
  • Est. Priority Date: 12/16/2005
  • Status: Active Grant
First Claim
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1. An implantable device comprising a protein patterning on said device, wherein the protein patterning comprises:

  • (a) a protein selected from the group consisting of fibronectin, laminin 5, elastin, silk elastin, collagen and combinations thereof, and(b) an agent selected from the group consisting of an adhesion molecule that includes a RGD motif, a chemoattractant of an endothelial cell, a NO releasing or generating agent, an agent that promotes endothelialization, or combinations thereof;

    and wherein the protein of (a) and the agent of (b) are chemically bonded to one another via a spacer.

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