Method and apparatus for calculating blood pressure with signal transformation

• US 7,594,893 B2
• Filed: 12/20/2005
• Issued: 09/29/2009
• Est. Priority Date: 08/31/2005
• Status: Active Grant

• Current Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd. (Excelsior Union Ltd.)
• Original Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd. (Excelsior Union Ltd.)
• Inventors: Zhang, Xu, Ye, Jilun, Tao, Bo
• Primary Examiner(s): Marmor, II; Charles A
• Assistant Examiner(s): D'ANGELO, MICHAEL J
• Application Number:
  US11/312,720
• Publication Number:
  US 20070049834A1
• Time in Patent Office: 1,379 Days
• Field of Search: 600/506, 600/485, 600/494, 600/500, 600/495, 600/547
• US Class Current: 600/500
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/02255 the pressure being controlled by plethysmographic signals, e.g. derived from optical sensors
• CPC Class Codes: A61B 5/7257 using Fourier transforms

Abstract

A method and an apparatus for calculating blood pressure with signal transformation are provided, wherein said apparatus comprises: a pressure sensor, a pressure and pulse wave amplification circuit, an A/D converter, a microprocessor, a control circuit, an air pump and a valve component connected with the cuff gas circuit, a signal processing module and a ratio analysis module; and the method includes the steps of carrying out signal transformation of a time sequence of a sampled PW digital signal, calculating a maximum amplitude value and a corresponding frequency value based on the transformed signal, taking the maximum amplitude value as a amplitude value under the present pressure, carrying out continuously signal transformation of the time sequences of the PW digital signals at different pressure in order to constitute a PW amplitude-pressure curve and obtain an average pressure and a corresponding pulse rate from the PW amplitude-pressure curve, and finally calculating the systolic pressure and diastolic pressure with ratio method. With the method and apparatus according to the present invention, the measurement error can be reduced in case of the shiver, muscular fibrillation and the like of the human body being examined, and the measurement accuracy of blood pressure can be improved.

Claims

1. A method for calculating blood pressure, comprising:

acquiring a plurality of frequency domain pulse wave (PW) maximum amplitude values and associated pressure measurements from respective frequency domain representations of time domain PW pressure signals obtained at different respective measurement pressures, wherein acquiring a PW maximum amplitude and associated pressure measurement comprises;

setting a pressure measurement device to a determined measurement pressure,

receiving a pressure signal and a set of PW pressure signals from the pressure measurement device, wherein the set of PW pressure signals are received over a predetermined time period,

constructing a PW time sequence comprising the set of PW pressure signals,

calculating a frequency domain representation of the PW time sequence, and

identifying a PW maximum amplitude value and PW frequency value in the frequency domain representation of the PW time sequence; and

calculating a blood pressure value using the plurality of frequency domain PW maximum amplitude values and associated pressure values.

2. The method of claim 1, wherein the frequency domain PW maximum amplitude value is identified as the maximum amplitude value of the frequency domain representation of the PW time sequence.

3. The method of claim 2, wherein identifying the frequency domain PW frequency value comprises identifying the frequency of the PW maximum amplitude value in the frequency domain representation of the PW time sequence.

4. The method of claim 1, wherein the blood pressure value comprises a systolic blood pressure value (PS) and a diastolic blood pressure value (PD), and wherein calculating the PS and PD comprises:

constructing a PW curve comprising the plurality of frequency domain PW amplitude values sequence and associated pressure measurements;

calculating a mean pressure and mean PW amplitude value (P0) using the PW curve; and

calculating the PS and PD values using the P0 value.

5. The method of claim 4, wherein the PS value is calculated by scaling the P0 value by a constant α

, and wherein α

ranges from 0.2 to 0.9, and wherein the PD value is calculated by scaling the P0 value by a constant β

, and wherein β

ranges from 0.2 to 0.8.

6. The method of claim 4, wherein constructing the PW curve further comprises:

normalizing the plurality of frequency domain PW amplitude values and associated pressure values;

constructing the PW curve by interpolation and weighted average processing performed on the normalized PW amplitude values.

7. The method of claim 1, wherein the frequency domain representation is calculated using one of a Chirp-Z transformation, a Fourier transform, and a discrete Fourier transform.

8. The method of claim 1, wherein 6 to 10 frequency domain PW maximum amplitude values are acquired, and wherein each of the 6 to 10 frequency domain PW maximum amplitude values are acquired at a different measurement pressure.

9. The method of claim 1, wherein the predetermined time period is 3 to 10 seconds.

10. An apparatus for calculating a blood pressure, comprising:

a pressure measurement device configured to acquire a plurality of sets of pulse wave (PW) pressure signals and associated pressure measurements, wherein each set of PW pressure signals and associated pressure measurements are acquired at different measurement pressures and for a predetermined time period;

a signal processing module configured to calculate a PW time sequence for each of the plurality of sets of PW pressure signals, to transform each of the PW time sequences into a respective frequency domain representation, and to identify within each frequency domain representation a frequency domain PW maximum amplitude value; and

a ratio analysis module configured to calculate a blood pressure value using the plurality of frequency domain PW maximum amplitude values and associated pressure values.

11. The apparatus of claim 10, wherein the ratio analysis module is configured to construct a PW curve comprising the PW maximum amplitude values and associated pressure measurements and to determine a mean PW amplitude value (P0) therefrom, and wherein the ratio analysis module is configured to calculate PS and PD values using the P0 value.

12. The apparatus of claim 11, wherein the ratio analysis module is configured to calculate the PS value by scaling the P0 value by a constant value α

, and wherein α

ranges from 0.2 to 0.9.

13. The apparatus of claim 11, wherein the ratio analysis module is configured to calculate the PD value by scaling the P0 value by a constant value β

, and wherein β

ranges from 0.2 to 0.8.

14. The apparatus of claim 11, wherein the ratio analysis module is configured to normalize the plurality of PW maximum amplitude values, and wherein to construct the PW curve, the ratio analysis module is configured to process the normalized PW maximum amplitude values using interpolation and weighted averaging.

15. The apparatus of claim 10, wherein the signal processing module is configured to calculate the frequency domain representation of each of the PW time sequences using a Chirp-Z transformation.

16. The apparatus of claim 10, wherein the signal processing module is configured to calculate the frequency domain representation of each of the PW time sequences using a Fourier transform.

17. The apparatus of claim 10, wherein the signal processing module is configured to calculate the frequency domain representation of each of the PW time sequences using a discrete Fourier transform.

18. The apparatus of claim 17, wherein the measurement device comprises a control unit to control the measurement pressure of the measurement device.

19. The apparatus of claim 10, wherein the measurement device is configured to acquire 6 to 10 sets of PW pressure signals and associated pressure measurements.

20. The apparatus of claim 10, wherein the measurement device comprises an air pump and valve, and wherein the control unit controls the measurement pressure of the measurement device using the air pump and valve.

21. The apparatus of claim 10, wherein the measurement device comprises an A/D converter to convert pressure measurements acquired by the measurement device into digital signals.