Bypass grafting method

• US 7,597,697 B1
• Filed: 07/11/2001
• Issued: 10/06/2009
• Est. Priority Date: 07/03/1991
• Status: Expired due to Fees

• Current Assignee: Lifeshield Sciences LLC (Acacia Research Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Maginot, Thomas J.
• Primary Examiner(s): PREBILIC, PAUL B
• Application Number:
  US09/903,831
• Time in Patent Office: 3,009 Days
• Field of Search: 604/8, 606/153, 606/154, 606/155, 623/1.11, 623/902, 623/903
• US Class Current: 606/153
• CPC Class Codes: A61B 17/11 for performing anastomosis; Buttons for anastomosis
• CPC Class Codes: A61B 2017/1107 for blood vessels
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/064 with special features to facilitate anastomotic coupling anastomosis of natural blood vessels A61B17/11
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: Y10S 623/902 Method of implanting
• CPC Class Codes: Y10S 623/903 Blood vessel

Abstract

Minimally invasive techniques utilized in bypass grafting are disclosed. For instance, a method of implanting an end portion of a graft in the body of a patient during a bypass grafting procedure includes the steps of (i) advancing a medical instrument within a circulatory system of said body, (ii) guiding a distal end of said medical instrument out of said circulatory system through an opening defined in said circulatory system after said medical instrument advancing step, (iii) advancing said end portion of said graft within said medical instrument after said guiding step, and (iv) securing said end portion of said graft to a blood vessel of said circulatory system after said end portion advancing step.

Claims

1. A method of locating a graft assembly including a blood flow conduit at an arteriotomy defined in a side wall of a blood vessel, with the graft assembly including (i) an orifice at an end of the blood flow conduit, and (ii) a plurality of arms attached to the blood flow conduit at the end thereof and extending away from the orifice, the method comprising the steps of:

locating the graft assembly within a delivery device;

extravascularly advancing the delivery device toward the arteriotomy while the graft assembly is located within the delivery device;

aligning the orifice at the end of the blood flow conduit with the arteriotomy; and

locating a first portion of each of the plurality of arms within the blood vessel with a second portion of each of the arms extending outside and away from the blood vessel through the arteriotomy defined in the side wall of the blood vessel;

wherein the first portion of each of the plurality of arms is located in a first position in relation to the graft assembly during the advancing step, and

wherein the first portion of each of the plurality of arms moves from the first position to a second position in which the first portion of each of the arms extends inside the blood vessel away from the arteriotomy defined therein after the advancing step while the second portion of each of the arms extends away from the blood vessel through the arteriotomy.

2. The method of claim 1, wherein the first portion of each of the plurality of arms moves from the first position to the second position due to spring action.

3. The method of claim 1 wherein the first portions of the plurality of arms includes four arms or a number of arms other than four extending away from the orifice of the graft.

4. The method of claim 1, wherein the first portion of each of the plurality of arms is maintained in the first position by an inner wall of the delivery device.

5. A method of locating a graft assembly including a blood flow conduit in relation to an arteriotomy defined in a side wall of a blood vessel, with the graft assembly including an orifice at an end of the blood flow conduit and a resilient support secured thereto about the orifice, the method comprising the steps of:

locating the graft assembly and resilient support within a delivery device;

extravascularly advancing the delivery device toward alignment with the arteriotomy with the graft assembly and resilient support located within the delivery device; and

removing the graft assembly and resilient support from the delivery device through the arteriotomy into the blood vessel after the advancing step;

wherein the resilient support is maintained in a first configuration during the advancing step; and

wherein the resilient support moves from the first configuration to a second configuration extending outwardly about the orifice inside the blood vessel due to spring action with the blood flow conduit extending through the arteriotomy away from the blood vessel after the removing step.

6. The method of claim 5, wherein after the removing step:

a first portion of the resilient support is located adjacent to an interior sidewall of the blood vessel with the resilient support positioned in the second configuration.

9. The method of claim 5, wherein:

the graft assembly further includes a flange portion disposed about the orifice at said end, and

at least some of the resilient support is positioned in contact with the flange portion.

10. The method of claim 9, wherein the at least some of the resilient support is integrally positioned within the flange portion.

11. The method of claim 5, wherein the resilient support includes a plurality of spring arms.

12. The method of claim 11, wherein the plurality of spring arms includes four spring arms or a number of spring arms other than four.

13. The method of claim 5, wherein the resilient support is maintained in the first configuration due to physical interaction with an inner wall of the delivery device.

14. The method of claim 5, further comprising the step of inhibiting movement of the blood flow conduit of the graft assembly in a direction outwardly through the arteriotomy and away from the blood vessel with the resilient support positioned in the second configuration.

7. A method of locating a graft assembly in relation to an arteriotomy defined in a blood vessel, with the graft assembly including a graft and a resilient support secured thereto, the method comprising the steps of:

locating the graft within a delivery device;

extravascularly advancing the delivery device toward the arteriotomy while the graft is located within the delivery device; and

removing the graft from the delivery device after the advancing step;

wherein the resilient support is maintained in a first configuration during the advancing step,

wherein the resilient support moves from the first configuration to a second expanded configuration due to spring action after the advancing step, and

wherein after the removing step;

a first portion of the resilient support is located adjacent to an interior sidewall of the blood vessel with the resilient support positioned in the second configuration, and a second portion of the resilient support extends through the arteriotomy in a direction away from the blood vessel with the resilient support positioned in the second configuration.

8. The method of claim 7, wherein after the removing step:

all of the first portion is located inside of the blood vessel, and

all of the second portion is located outside of the blood vessel.

15. A method of placing a graft assembly including a blood flow conduit at an arteriotomy defined in a sidewall of a blood vessel, with the graft assembly including an orifice at an end of the blood flow conduit and a plurality of spring arms each having a first portion extending away from the orifice and having a second portion extending along the blood flow conduit, the method comprising the steps of:

extravascularly aligning the orifice of the graft assembly with the arteriotomy; and

locating the plurality of spring arms through the arteriotomy with the first portions thereof adjacent to an inside wall of the blood vessel and with the blood flow conduit and the second portions of the spring arms extending through the arteriotomy outside and away from the blood vessel.

16. The method of claim 15, wherein:

the graft assembly further includes a flange portion disposed about the orifice, and

the first portion of each of the plurality of spring arms is positioned in contact with the flange portion.

17. The method of claim 16, wherein at least the first portion of each of the plurality of spring arms is integrally positioned within the flange portion, and the second portion of each of the plurality of spring arms extends along the blood flow conduit through the arteriotomy outside and away from the blood vessel.

18. The method of claim 15, further comprising the steps of:

prior to the aligning step, locating the graft assembly within a delivery device; and

extravascularly advancing the delivery device toward alignment with the arteriotomy while the graft assembly is located within the delivery device,

wherein each of the plurality of spring arms is confined within the delivery device during the advancing step, and

wherein the first portion of each of the plurality of spring arms moves to an expanded condition extending about the arteriotomy within the blood vessel after the advancing step.

19. The method of claim 18, wherein the first portion of each of the plurality of spring arms is maintained in the confined position due to physical interaction with an inner wall of the delivery device.

20. The method of claim 15, further comprising the step of inhibiting movement of the graft assembly in a direction outwardly through the arteriotomy and away from the blood vessel due to physical interaction of the first portions of the plurality of spring arms against an interior wall of the blood vessel.

21. An anastomosis method for placing a conduit assembly adjacent to an arteriotomy defined in a blood vessel, wherein the conduit assembly includes a blood flow conduit and a resilient member secured to and extending radially outwardly about an orifice at an end of the blood flow conduit, the method comprising:

(i) extravascularly aligning the orifice of the blood flow conduit with the arteriotomy, (ii) locating a first portion of the resilient member within the blood vessel, and (iii) locating a second portion of the resilient member extending through the arteriotomy outside and away from the blood vessel; and

wherein locating the first portion includes the steps of;

confining the resilient member to a first configuration for insertion through the arteriotomy;

advancing the first portion of the resilient member through the arteriotomy while the resilient member is confined in the first configuration; and

expanding the resilient member from the confined first configuration to a second expanded configuration extending radially outwardly about the arteriotomy within the blood vessel due to spring action of the resilient member after the advancing step.

22. A method of locating a conduit assembly in relation to an opening defined in a blood vessel, with the conduit assembly including a blood flow conduit and a plurality of struts, comprising the steps of:

advancing the plurality of struts into the blood vessel through the opening;

aligning an orifice of the blood flow conduit with the opening defined in the blood vessel;

urging each of the plurality of struts against the interior wall of the blood vessel, wherein the urging step includes a step of placing a stent within the blood vessel and adjacent to the plurality of struts to urge the struts against the interior wall of the blood vessel.

23. A method of locating a conduit assembly in relation to an opening defined in a sidewall of a blood vessel, with the conduit assembly including a blood flow conduit and a plurality of struts, the method comprising the steps of:

locating the blood flow conduit within a delivery device;

extravascularly moving the delivery device toward the opening defined in the blood vessel with the blood flow conduit located within the delivery device and each of the plurality of struts located in a first physical arrangement confined within the delivery device;

advancing the plurality of struts into the blood vessel through the opening;

aligning an orifice of the blood flow conduit with the opening defined in the blood vessel; and

reconfiguring each of the plurality of struts from the first physical arrangement to a second physical arrangement extending within the blood vessel about the opening therein, with the blood flow conduit extending through the opening for conducting blood flow away from the blood vessel.

24. The method of claim 23, wherein each of the plurality of struts moves from the first physical arrangement to the second physical arrangement due to spring action.

25. A method of connecting a conduit assembly adjacent to an arteriotomy defined in a blood vessel, the conduit assembly including a blood flow conduit and a resilient support secured thereto about an orifice in an end thereof, the method comprising the steps of:

confining the resilient support in a first configuration for insertion through the arteriotomy;

extravascularly advancing the resilient support and blood flow conduit partially through the arteriotomy with the resilient support in the first configuration, and with the blood flow conduit extending through the arteriotomy to outside and away from the blood vessel; and

after the advancing step, releasing the resilient support to move from the first configuration to a second configuration extending about the arteriotomy inside the blood vessel due to spring action of the resilient support, with the blood flow conduit extending through the arteriotomy.

26. The method of claim 25, further comprising the steps of:

prior to the advancing step, locating the blood flow conduit and resilient support in the first configuration within a delivery device; and

extravascularly advancing the delivery device toward the arteriotomy in alignment therewith while the blood flow conduit and resilient support in the first configuration are located within the delivery device.

33. The method of claim 25, further comprising the step of inhibiting movement of the blood flow conduit through the arteriotomy in a direction away from the blood vessel due to physical interaction between the resilient support and an inner wall of the blood vessel after the releasing step.

27. A method of locating a graft assembly in relation to an arteriotomy defined in a blood vessel, with the graft assembly including a graft and a resilient support secured thereto, the method comprising the steps of:

locating the graft within a delivery device;

advancing the delivery device toward the arteriotomy while the graft is located within the delivery device in a first configuration; and

removing the graft from the delivery device after the advancing step to move the resilient support from the first configuration to a second configuration due to spring action, with some of a first portion of the resilient support located adjacent to a sidewall within the blood vessel, and with some of a second portion of the resilient support located outside the blood vessel and extending in a direction away from the blood vessel.

28. A method of locating a graft assembly in relation to an aortotomy with the graft assembly including a graft and a resilient support secured thereto, the method comprising the steps of:

locating the graft within a delivery device;

advancing the delivery device toward the aortotomy while the graft is located within the delivery device; and

removing the graft from the delivery device after the advancing step,

wherein the resilient support is maintained in a first configuration during the advancing step, and

wherein the resilient support moves from the first configuration to a second configuration due to spring action after the advancing step.

29. A method of placing a conduit assembly adjacent to an aortotomy, the conduit assembly including a blood flow conduit and a resilient support secured thereto, the method comprising the steps of:

bending the resilient support into a first configuration;

advancing the resilient support partially through the aortotomy while the resilient support is in the first configuration; and

allowing the resilient support to move from the first configuration to a second configuration due to spring action after the advancing step.

30. A method of placing a conduit assembly adjacent to an arteriotomy defined in a blood vessel, the conduit assembly including a blood flow conduit and a resilient support secured thereto, the method comprising the steps of:

bending the resilient support into a first configuration;

advancing the resilient support partially through the arteriotomy while the resilient support is in the first configuration; and

after the advancing step, allowing the resilient support to move from the first configuration to a second configuration due to spring action while a first portion of the resilient support is positioned on a first side of the arteriotomy and a second portion of the resilient support is positioned on a second side of the arteriotomy.

31. The method of claim 30, wherein:

the first portion of the resilient support is positioned within the blood vessel, and

the second portion of the resilient support is positioned outside of the blood vessel.

32. The method of claim 31, wherein the first portion of the resilient support includes a plurality of support arms.