System and method for analyte measurement employing maximum dosing time delay
First Claim
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1. A method of performing a measurement on a biological fluid in a test strip comprising:
- providing a biological fluid test strip includinga capillary fill chamber extending a length along the test strip from an intake opening to a terminus,a first pair of electrodes in operative communication with the chamber, anda second pair of electrodes in operative communication with the chamber;
dosing the test strip with a biological fluid effective to cause the biological fluid to flow from the intake opening toward the terminus;
applying a first test signal to at least one of the first pair of electrodes;
measuring a first response to the first test signal;
maintaining the first pair of electrodes in an inoperative state after the measuring the first response;
applying a second test signal to at least one of the second pair of electrodes, wherein the second test signal is a signal having an AC component;
measuring a second response to the second test signal to determine sample sufficiency of the dose of the biological fluid; and
performing a measurement upon the biological fluid after the measuring the second response.
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Abstract
A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.
634 Citations
16 Claims
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1. A method of performing a measurement on a biological fluid in a test strip comprising:
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providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a first pair of electrodes in operative communication with the chamber, and a second pair of electrodes in operative communication with the chamber; dosing the test strip with a biological fluid effective to cause the biological fluid to flow from the intake opening toward the terminus; applying a first test signal to at least one of the first pair of electrodes; measuring a first response to the first test signal; maintaining the first pair of electrodes in an inoperative state after the measuring the first response; applying a second test signal to at least one of the second pair of electrodes, wherein the second test signal is a signal having an AC component; measuring a second response to the second test signal to determine sample sufficiency of the dose of the biological fluid; and performing a measurement upon the biological fluid after the measuring the second response. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method of indicating acceptable fill time of a biological fluid in a test strip comprising:
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providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a first pair of electrodes in operative communication with the chamber, a second pair of electrodes in operative communication with the chamber; and a third pair of electrodes in operative communication with the chamber; dosing the test strip with a biological fluid effective to cause the biological fluid to flow from the intake opening toward the terminus; flowing a biological fluid from the opening toward the terminus; first determining when the biological fluid contacts the first pair of electrodes; second determining when the biological fluid contacts the second pair of electrodes; determining a fill time value based upon the first determining and the second determining; comparing the fill time value to a predetermined value; and third measuring a first analyte concentration of the biological fluid using the third pair of electrodes; wherein the first pair of electrodes and the second pair of electrodes are not used to measure the first analyte concentration or any second analyte concentration. - View Dependent Claims (9, 10, 11, 12)
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13. A method of performing a measurement on a biological fluid in a test strip comprising:
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providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a first pair of electrodes in operative communication with the chamber; a second pair of electrodes in operative communication with the chamber; and a third pair of electrodes in operative communication with the chamber; dosing the test strip with a biological fluid effective to cause the biological fluid to flow from the intake opening toward the terminus; applying a first test signal to at least one of the first pair of electrodes; measuring a first response to the first test signal; maintaining the first pair of electrodes in an inoperative state after the measuring the first response; applying a second test signal to at least one of the second pair of electrodes; measuring a second response to the second test signal; determining a fill time of the chamber based upon the first response and the second response; applying a measurement test signal to at least one of the third pair of electrodes after the measuring the second response; measuring a third response to the third test signal; and determining a first concentration of an analyte in the biological fluid using the third response; wherein the first pair of electrodes and the second pair of electrodes are not used to measure the first analyte concentration or any second analyte concentration. - View Dependent Claims (14, 15, 16)
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Specification