Apparatus for selectively holding and releasing an object in an analysis system

• US 7,597,845 B2
• Filed: 08/23/2004
• Issued: 10/06/2009
• Est. Priority Date: 08/23/2004
• Status: Expired due to Fees

• Current Assignee: Beckman Coulter Incorporated (Danaher Corporation)
• Original Assignee: Beckman Coulter Incorporated (Danaher Corporation)
• Inventors: Domack, Thomas E.
• Primary Examiner(s): Griffin; Walter D
• Assistant Examiner(s): Ramdhanie; Bobby
• Application Number:
  US10/923,975
• Publication Number:
  US 20060039822A1
• Time in Patent Office: 1,870 Days
• Field of Search: 422/63
• US Class Current: 422/63
• CPC Class Codes: G01N 1/2813 Producing thin layers of samples on a substrate, e.g. smearing, spinning-on G01N1/30 takes precedence
• CPC Class Codes: G01N 2035/00039 Transport arrangements specific to flat sample substrates, e.g. pusher blade
• CPC Class Codes: G01N 2035/0477 Magnetic
• CPC Class Codes: G01N 35/0099 comprising robots or similar manipulators robots per se B25J

Abstract

An apparatus for selectively holding and releasing an object in an analysis system is set forth. The apparatus comprises first and second arm assemblies that are mounted for rotation about a corresponding pair of axes. Each arm assembly includes an object holding end and a magnetic end disposed opposite one another about the respective axis. A magnetic drive is provided to magnetically induce rotation of the magnetic ends of the first and second arm assemblies about their respective axes between an open state in which the holding ends are distal one another to allow placement of the object that is to be held therebetween and a closed state in which the holding ends are driven proximate the object. The apparatus may be readily adapted to receive and hold a variety of objects, such as test tubes, vials, microscope slides, etc.

Claims

1. An apparatus for selectively holding and releasing an object in an analysis system, the apparatus comprising:

a first arm mounted for rotation about a first axis, said first arm having an object holding end and a magnetic end disposed opposite one another about said first axis, wherein said first axis is intermediate to said object holding end and said magnetic end of said first arm;

a second arm mounted for rotation about a second axis that is generally parallel to said first axis, said second arm having an object holding end and a magnetic end disposed opposite one another about said second axis, wherein said second axis is intermediate to said object holding end and said magnetic end of said second arm; and

a magnetic drive adapted to magnetically induce rotation of said magnetic ends of said first and second arms about said first and second axes, respectively, wherein said magnetically induced rotation axially rotates said object holding ends.

2. An apparatus as claimed in claim 1 and further comprising a spacing adjustment mechanism disposed to limit movement of said first arm toward said second arm.

3. An apparatus as claimed in claim 1 wherein said magnetic ends of said first and second arms rotate between a first position in which said holding ends are distal to an object that is to be held and a second position in which said holding ends are proximate to said object.

4. An apparatus as claimed in claim 1 wherein said magnetic ends of said first and second members comprise permanent magnets.

5. An apparatus as claimed in claim 4 wherein said permanent magnets of said magnetic ends of said first and second arms are arranged so that they are magnetically attracted to one another to bias said magnetic portions toward one another.

6. An apparatus as claimed in claim 1 wherein said magnetic drive comprises:

a permanent drive magnet; and

a motor drive connected to said permanent drive magnet, said motor drive directing said permanent drive magnet between at least a first position in which said magnetic ends of said first and second arms rotate toward one another as a result of the position of said permanent drive magnet and a second position in which said magnetic ends of said first and second arms are rotated away from one another as a result of the position of said permanent drive magnet.

7. An apparatus as claimed in claim 6 wherein said motor drive comprises a linear stepper motor.

8. An apparatus as claimed in claim 6 wherein said permanent drive magnet is oriented to repel said magnetic ends of said first and second arms when said permanent drive magnet is disposed between said magnetic ends.

9. An apparatus as claimed in claim 1 wherein said magnetic drive comprises an electromagnet.

10. An apparatus as claimed in claim 9 and further comprising a control unit adapted to control electric current flow through said electromagnet.

11. An apparatus for selectively holding and releasing a carrier in an analysis unit, the carrier being adapted to hold a sample for analysis, the apparatus comprising:

a mounting bed adapted to support the carrier;

a first arm assembly having an arm portion at a first end thereof and a magnetic portion at a second end thereof, said first arm assembly being mounted for rotation about a first axis, wherein said first axis is intermediate to said first end and said second end of said first arm assembly;

a second arm assembly having an arm portion at a first end thereof and a magnetic portion at a second end thereof, said second arm assembly being mounted for rotation about a second axis that is generally parallel to said first axis, and wherein said second axis is intermediate to said first end and said second end of said second arm assembly; and

a magnetic drive adapted to magnetically induce rotation of said magnetic portions of said first and second arm assemblies toward and away from one another about said first and second axes thereby causing corresponding rotation of said arm portions of said first and second arm assemblies between a first position in which the carrier may be accepted upon said mounting bed and a second position in which the carrier may be secured upon said mounting bed with the assistance of said arm portions.

12. An apparatus as claimed in claim 11 and further comprising a spacing adjustment mechanism disposed to limit movement of said first arm assembly toward said second arm assembly when said first and second arm assemblies are in said second position.

13. An apparatus as claimed in claim 11 wherein said magnetic portions of said first and second arm assemblies comprise permanent magnets.

14. An apparatus as claimed in claim 13 wherein said permanent magnets of said magnetic portions of said first and second arm assemblies are arranged so that they are magnetically attracted to one another to bias said magnetic portions toward one another.

15. An apparatus as claimed in claim 11 wherein said magnetic drive comprises:

a permanent drive magnet; and

a motor drive connected to said permanent drive magnet, said motor drive directing said permanent drive magnet between at least a first position in which said magnetic portions of said first and second arm assemblies rotate toward one another as a result of the position of said permanent drive magnet and a second position in which said magnetic portions of said first and second arm assemblies are rotated away from one another as a result of the position of said permanent drive magnet.

16. An apparatus as claimed in claim 15 wherein said motor drive comprises a linear stepper motor.

17. An apparatus as claimed in claim 14 wherein said magnetic drive comprises:

a permanent drive magnet; and

a motor drive connected to said permanent drive magnet, said motor drive directing said permanent magnet between at least a first position in which said permanent drive magnet is disposed between said permanent magnets of said first and second arm assemblies and a second position in which said permanent drive magnet is moved away from between said permanent magnets of said first and second arm assemblies.

18. An apparatus as claimed in claim 17 wherein said motor drive comprises a linear stepper motor.

19. An apparatus as claimed in claim 17 wherein said permanent drive magnet is oriented to repel said permanent magnets of said first and second arm assemblies when said permanent drive magnet is disposed between said magnetic portions.

20. An apparatus as claimed in claim 14 wherein said magnetic drive comprises an electromagnet.

21. An apparatus as claimed in claim 20 and further comprising a control unit adapted to control electric current flow through said electromagnet.

22. An apparatus for transporting a slide in an analysis unit, the apparatus comprising:

a slide carriage assembly comprising;

a mounting bed adapted to support the slide,

a first arm assembly having an arm portion at a first end thereof and a magnetic portion at a second end thereof, said first arm assembly being mounted for rotation about a first axis, wherein said first axis is intermediate to said first end and said second end of said first arm assembly,

a second arm assembly having an arm portion at a first end thereof and a magnetic portion at a second end thereof, said second arm assembly being mounted for rotation about a second axis that is generally parallel to said first axis, and wherein said second axis is intermediate to said first end and said second end of said second arm assembly,

a magnetic drive adapted to magnetically induce rotation of said magnetic portions of said first and second arm assemblies toward and away from one another about said first and second axes thereby causing corresponding rotation of said arm portions of said first and second arm assemblies between a first position in the slide may be accepted upon said mounting bed and a second position in which the slide may be secured upon said mounting bed with the assistance of said arm portions; and

a carriage drive connected to move said slide carriage assembly between a plurality of positions within the analysis unit.

23. An apparatus as claimed in claim 22 and further comprising a spacing adjustment mechanism disposed to limit movement of said first arm assembly toward said second arm assembly when said first and second arm assemblies are in said second position.

24. An apparatus as claimed in claim 22 wherein said magnetic portions of said first and second arm assemblies comprise permanent magnets.

25. An apparatus as claimed in claim 24 wherein said permanent magnets of said magnetic portions of said first and second arm assemblies are arranged so that they are magnetically attracted to one another to bias said magnetic portions toward one another.

26. An apparatus as claimed in claim 22 wherein said magnetic drive comprises:

a permanent drive magnet; and

a motor drive connected to said permanent drive magnet, said motor drive directing said permanent drive magnet between at least a first position in which said magnetic portions of said first and second arm assemblies rotate toward one another as a result of the position of said permanent drive magnet and a second position in which said magnetic portions of said first and second arm assemblies are rotated away from one another as a result of the position of said permanent drive magnet.

27. An apparatus as claimed in claim 26 wherein said motor drive comprises a linear stepper motor.

28. An apparatus as claimed in claim 25 wherein said magnetic drive comprises:

a permanent drive magnet; and

a motor drive connected to said permanent drive magnet, said motor drive directing said permanent magnet between at least a first position in which said permanent drive magnet is disposed between said permanent magnets of said first and second arm assemblies and a second position in which said permanent drive magnet is moved away from between said permanent magnets of said first and second arm assemblies.

29. An apparatus as claimed in claim 28 wherein said motor drive comprises a linear stepper motor.

30. An apparatus as claimed in claim 28 wherein said permanent drive magnet is oriented to repel said permanent magnets of said first and second arm assemblies when said permanent drive magnet is disposed between said permanent magnets.

31. An apparatus as claimed in claim 25 wherein said magnetic drive comprises an electromagnet.

32. An apparatus as claimed in claim 31 and further comprising a control unit adapted to control electric current flow through said electromagnet.

33. An apparatus for selectively holding and releasing a carrier during transport in an analysis unit, the apparatus comprising:

a mounting bed adapted to contact the carrier;

a first clamp member mounted for rotation about a first axis, said first clamp member having a carrier gripping end and a magnetic end disposed on opposite sides of said first axis;

a second clamp member mounted for rotation about a second axis that is generally parallel to said first axis, said second clamp member having a carrier gripping end and a magnetic end disposed on opposite sides of said second axis; and

a magnetic drive adapted to magnetically induce rotation of said magnetic ends of said first and second clamp members about said first and second axes, respectively, to thereby cause the axial rotation of the clamp members to secure the carrier to said mounting bed.

34. An apparatus as claimed in claim 33 wherein said magnetic ends of said first and second clamp members rotate between a first position in which said gripping ends are distal said mounting bed and a second position in which said gripping ends are proximate said mounting bed.

35. An apparatus as claimed in claim 34 wherein said gripping ends are adapted to clamp the carrier against said mounting bed in said second position.

36. An apparatus as claimed in claim 33 wherein said magnetic ends of said first and second clamp members comprise permanent magnets.

37. An apparatus as claimed in claim 36 wherein said permanent magnets of said magnetic ends of said first and second clamp members are arranged so that they are magnetically attracted to one another to bias said magnetic portions toward one another.

38. An apparatus as claimed in claim 33 wherein said magnetic drive comprises:

a permanent drive magnet; and

a motor drive connected to said permanent drive magnet, said motor drive directing said permanent drive magnet between at least a first position in which said magnetic ends of said first and second clamp members rotate toward one another as a result of the position of said permanent drive magnet and a second position in which said magnetic ends of said first and second clamp members are rotated away from one another as a result of the position of said permanent drive magnet.

39. An apparatus as claimed in claim 38 wherein said motor drive comprises a linear stepper motor.

40. An apparatus as claimed in claim 38 wherein said permanent drive magnet is oriented to repel said magnetic ends of said first and second clamp members when said permanent drive magnet is disposed between said magnetic ends.

41. An apparatus as claimed in claim 33 wherein said magnetic drive comprises an electromagnet.

42. An apparatus as claimed in claim 41 and further comprising a control unit adapted to control electric current flow through said electromagnet.

43. An analysis system, comprising:

a slide adapted to receive a sample to be analyzed;

a first arm mounted for rotation about a first axis, said first arm having a slide clamping portion and a magnetic portion, wherein said first axis is intermediate to said slide clamping portion and said magnetic portion of said first arm;

a second arm mounted for rotation about a second axis, said second arm having a slide clamping portion and a magnetic portion, wherein said second axis is intermediate to said slide clamping portion and said magnetic portion of said second arm;

a mounting bed adapted to support said slide, said mounting bed disposed intermediate to said first arm and said second arm; and

a magnetic drive adapted to magnetically induce rotation of the magnetic portions of said first and second arms about the first and second axes, respectively, wherein said magnetically induced rotation axially rotates said object holding ends.

44. An analysis system as claimed in claim 43, wherein said first and second arms rotate between a first position in which the slide clamping portions clamp said slide to said mounting bed and a second position in which said slide is not clamped.

45. An analysis system as claimed in claim 43, further comprising a space adjustment member disposed perpendicular to the first and second axes.

46. An analysis system as claimed in claim 43, wherein the slide clamping portions are disposed at a first end of said first and second arms.

47. An analysis system as claimed in claim 46, wherein the magnetic portions are disposed at a second end of said first and second arms.

48. An analysis system as claimed in claim 43, wherein the magnetic portions comprise permanent magnets.