Apparatus and methods for delivery of medicament to a respiratory system
First Claim
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1. An apparatus for delivery of a medicament to a respiratory system, the apparatus comprising:
- a reservoir for a liquid medicament for delivery to a respiratory system, the reservoir having an upper liquid medicament inlet port and a lower medicament outlet;
an aerosol generator at the medicament outlet of the reservoir for aerosolizing the liquid medicament, wherein;
the reservoir has a lower portion substantially shaped and sloped towards the aerosol generator to promote flow of the liquid medicament towards the aerosol generator at the medicament outlet by gravitational action; and
the aerosol generator comprises a vibratable member having a plurality of apertures extending between a first surface and a second surface, the first surface being adapted to receive the liquid medicament and the aerosol generator being configured to generate an aerosol at the second surface;
a connector for entraining the aerosolized medicament from the aerosol generator with a gas, the connector being releasably mounted to the reservoir, wherein the connector comprises a gas conduit having a gas-conduit inlet, a gas-conduit outlet and an aerosol supply conduit for delivering the aerosolized medicament from the aerosol generator into the gas conduit to entrain the aerosolized medicament with a gas; and
a respiratory conduit connecting the outlet of the gas conduit to the respiratory system, wherein the respiratory conduit is rotatable about a longitudinal axis of the outlet of the gas conduit, whereby the reservoir may be maintained at suitable orientation that enables gravitational flow of liquid medicament from the reservoir to the aerosol generator,wherein the liquid medicament inlet port is adapted to mate with a delivery tip of a supply container, whereby liquid medicament can be delivered into the reservoir from the supply container without dismounting parts of the apparatus.
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Abstract
Apparatus and methods are provided for delivery of a medicament to a respiratory system. A reservoir is provided for a liquid medicament with the reservoir having a liquid medicament inlet port and a medicament outlet. An aerosol generator is provided at the medicament outlet of the reservoir for aerosolizing the liquid medicament. A connector entrains the aerosolized medicament from the aerosol generator with a gas.
578 Citations
27 Claims
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1. An apparatus for delivery of a medicament to a respiratory system, the apparatus comprising:
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a reservoir for a liquid medicament for delivery to a respiratory system, the reservoir having an upper liquid medicament inlet port and a lower medicament outlet; an aerosol generator at the medicament outlet of the reservoir for aerosolizing the liquid medicament, wherein; the reservoir has a lower portion substantially shaped and sloped towards the aerosol generator to promote flow of the liquid medicament towards the aerosol generator at the medicament outlet by gravitational action; and the aerosol generator comprises a vibratable member having a plurality of apertures extending between a first surface and a second surface, the first surface being adapted to receive the liquid medicament and the aerosol generator being configured to generate an aerosol at the second surface; a connector for entraining the aerosolized medicament from the aerosol generator with a gas, the connector being releasably mounted to the reservoir, wherein the connector comprises a gas conduit having a gas-conduit inlet, a gas-conduit outlet and an aerosol supply conduit for delivering the aerosolized medicament from the aerosol generator into the gas conduit to entrain the aerosolized medicament with a gas; and a respiratory conduit connecting the outlet of the gas conduit to the respiratory system, wherein the respiratory conduit is rotatable about a longitudinal axis of the outlet of the gas conduit, whereby the reservoir may be maintained at suitable orientation that enables gravitational flow of liquid medicament from the reservoir to the aerosol generator, wherein the liquid medicament inlet port is adapted to mate with a delivery tip of a supply container, whereby liquid medicament can be delivered into the reservoir from the supply container without dismounting parts of the apparatus. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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Specification