Microfluidic valve having free-floating member and method of fabrication

• US 7,600,533 B2
• Filed: 08/10/2007
• Issued: 10/13/2009
• Est. Priority Date: 08/10/2006
• Status: Expired due to Fees

• Current Assignee: California Institute of Technology
• Original Assignee: California Institute of Technology
• Inventors: Tai, Yu-Chong, Rodger, Damien C., Chen, Po-Jui, Humayun, Mark S.
• Primary Examiner(s): RIVELL, JOHN A
• Application Number:
  US11/837,450
• Publication Number:
  US 20080035875A1
• Time in Patent Office: 795 Days
• Field of Search: 137/533.19, 137/859, 137/516.25, 137/516.27, 251/367, 251/368
• US Class Current: 137/516.25
• CPC Class Codes: F16K 15/144 the closure elements being fixed along all or a part of their periphery
• CPC Class Codes: F16K 99/0005 Lift valves
• CPC Class Codes: F16K 99/0015 Diaphragm or membrane valves
• CPC Class Codes: F16K 99/0057 the fluid being the circulating fluid itself, e.g. check valves
• CPC Class Codes: Y10T 137/0497 Fluid actuated or retarded
• CPC Class Codes: Y10T 137/7866 Plural seating
• CPC Class Codes: Y10T 137/7904 Reciprocating valves
• CPC Class Codes: Y10T 137/7914 Cage
• CPC Class Codes: Y10T 29/49409 Valve seat forming

Abstract

Micro check valves having a free-floating member for controlling flow of fluid in microfluidic and biomedical applications and methods of fabrication. A micro check valve includes a valve seat, a valve cap that contacts the valve seat and an untethered floating member that can move between the valve seat and the valve cap. Certain micro check valves have zero cracking pressure and no reverse leakage. Certain other valves may be configured to permit flow of fluid within a pressure range. The floating member can be solid or define an orifice, and the valve seat can have one or two levels. Valves can be configured to allow fluid to flow when the floating member is pushed by fluid against the valve cap or against the valve seat. The valve seat may be silicon or another material that is compatible with micromachining processes, and the valve cap and the floating member may be a polymer such as Parylene.

Claims

1. A micro check valve for controlling flow of a fluid, comprising:

a multi-level valve seat comprised of a substrate material, the multi-level valve seat having a first surface at a first level and a second surface at a second, lower level;

a valve cap disposed on the first surface, a space being defined between the valve seat and the valve cap; and

a floating member movable in the space between the multi-level valve seat and the valve cap by application of pressure on the floating member by a fluid to passively control flow of the fluid through the multi-level valve seat and the valve cap, wherein the multi-level valve seat, the valve cap and the floating member are configured to permit flow of the fluid when the fluid pressure is between a threshold pressure and a cut-off pressure and to stop flow of the fluid when the fluid pressure exceeds the cut-off pressure.

2. The micro check valve of claim 1, wherein the valve seat defines a port and the valve cap defines at least one orifice, the port and the at least one orifice being in fluid communication with each other.

3. The micro check valve of claim 1, wherein the floating member is solid.

4. The micro check valve of claim 3, wherein the fluid cannot flow through the port when the floating member is pushed by the fluid against the valve seat.

5. The micro check valve of claim 1, wherein the substrate material is silicon and the valve cap and the floating member are a polymer material.

6. The micro check valve of claim 1, wherein the valve seat, the valve cap and the floating member are configured to control the flow of a bodily fluid, water, a solution, or a drug or medication.

7. The micro check valve of claim 1, wherein the floating member is movable between the first surface of the valve seat and the valve cap.

8. A micro check valve for controlling flow of a fluid, comprising:

a multi-level valve seat comprised of a substrate material, the multi-level valve seat having a first surface at a first level and a second surface at a second, lower level;

a valve cap disposed on the first surface, a space being defined between the valve seat and the valve cap; and

a floating member movable in the space between the multi-level valve seat and the valve cap by application of pressure on the floating member by a fluid to passively control flow of the fluid through the multi-level valve seat and the valve cap, wherein the valve seat defines a fluid port and at least one fluid channel in fluid communication with the fluid port, and the floating member can bend under fluid pressure between a flat shape for temporarily sealing the at least one fluid channel and an arcuate shape.

9. The micro check valve of claim 8, wherein the floating member can bend under fluid pressure below the first surface and towards the second surface in order to open the at least one fluid channel and permit fluid to flow through the fluid channel and the fluid port.

10. The micro check valve of claim 9, wherein the floating member can bend further under fluid pressure to contact the second surface and seal the port to block fluid from flowing through the valve seat.

11. The micro check valve of claim 8, wherein the valve cap defines at least one orifice, the fluid port and the at least one orifice being in fluid communication with each other.

12. The micro check valve of claim 8, wherein the floating member is solid.

13. The micro check valve of claim 12, wherein the fluid cannot flow through the port when the floating member is pushed by the fluid against the valve seat.

14. The micro check valve of claim 8, wherein the substrate material is silicon and the valve cap and the floating member are a polymer material.

15. The micro check valve of claim 8, wherein the valve seat, the valve cap and the floating member are configured to control the flow of a bodily fluid, water, a solution, or a drug or medication.

16. The micro check valve of claim 8, wherein the floating member is movable between the first surface of the valve seat and the valve cap.

17. A micro check valve for controlling flow of a fluid, comprising:

a multi-level valve seat comprised of a substrate material, the multi-level valve seat having a first surface at a first level and a second surface at a second, lower level;

a valve cap disposed on the first surface, a space being defined between the valve seat and the valve cap; and

a floating member movable in the space between the multi-level valve seat and the valve cap by application of pressure on the floating member by a fluid to passively control flow of the fluid through the multi-level valve seat and the valve cap, wherein the floating member is bendable between a flat configuration and an arcuate configuration in which a portion of the floating member can contact the second surface by application of pressure on the floating member by a fluid.

18. The micro check valve of claim 17, wherein the valve seat defines a port and the valve cap defines at least one orifice, the port and the at least one orifice being in fluid communication with each other.

19. The micro check valve of claim 17, wherein the floating member is solid.

20. The micro check valve of claim 17, wherein the fluid cannot flow through the port when the floating member is pushed by the fluid against the valve seat.

21. The micro check valve of claim 17, wherein the substrate material is silicon and the valve cap and the floating member are a polymer material.

22. The micro check valve of claim 17, wherein the valve seat, the valve cap and the floating member are configured to control the flow of a bodily fluid, water, a solution, or a drug or medication.

23. The micro check valve of claim 17, wherein the floating member is movable between the first surface of the valve seat and the valve cap.