Multi-cap reservoir devices for controlled release or exposure of reservoir contents
First Claim
1. A device for the controlled release or exposure of reservoir contents comprising:
- a substrate;
at least one reservoir disposed in the substrate, the reservoir having two or more openings on the same side of the substrate;
reservoir contents located in the reservoir;
two or more discrete, electrically conductive reservoir caps, each reservoir cap sealingly covering a single reservoir opening; and
control means for selectively disintegrating or permeabilizing the reservoir caps to permit release or exposure of the reservoir contents via said two or more openings,wherein the substrate comprises at least one reservoir cap support extending over the reservoir contents in said at least one reservoir, the reservoir cap support supporting in part said two or more reservoir caps.
5 Assignments
0 Petitions
Accused Products
Abstract
Reservoir-based devices are provided in which an individual reservoir has at least two openings with a support structure therebetween and closed by reservoir caps covering the openings to control release or exposure of reservoir contents. In one embodiment, the device is an implantable medical device and provides for the controlled release of drug or exposure of a sensor. The device includes a substrate; at least one reservoir disposed in the substrate, the reservoir having two or more openings; reservoir contents located in the reservoir; two or more discrete reservoir caps, each reservoir cap sealingly covering at least one of the reservoir openings; and control means for selectively disintegrating or permeabilizing the reservoir caps.
172 Citations
31 Claims
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1. A device for the controlled release or exposure of reservoir contents comprising:
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a substrate; at least one reservoir disposed in the substrate, the reservoir having two or more openings on the same side of the substrate; reservoir contents located in the reservoir; two or more discrete, electrically conductive reservoir caps, each reservoir cap sealingly covering a single reservoir opening; and control means for selectively disintegrating or permeabilizing the reservoir caps to permit release or exposure of the reservoir contents via said two or more openings, wherein the substrate comprises at least one reservoir cap support extending over the reservoir contents in said at least one reservoir, the reservoir cap support supporting in part said two or more reservoir caps. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A device for the controlled release or exposure of reservoir contents comprising:
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a substrate having a reservoir which has a first opening and a second opening; reservoir contents located in the reservoir; first and second discrete reservoir caps, the first discrete reservoir cap sealingly covering the first opening and the second discrete reservoir cap sealingly covering the second opening; a source of electric power and circuitry for selectively disintegrating the first and second discrete reservoir caps; and at least one reservoir cap support which extends over the reservoir contents, which defines the first and second openings, and which supports the first and second discrete reservoir caps. - View Dependent Claims (23, 24, 25, 26)
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27. An implantable medical device comprising:
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a substrate having a reservoir defined therein, said reservoir having two or more discrete openings; a pharmaceutical agent, sensor, or sensor component located within said at least one reservoir; two or more discrete reservoir caps, each reservoir cap comprising an electrically conductive material and closing off a single one of said two or more discrete openings of said reservoir; an electrical input lead connected to each of said two or more reservoir caps; an electrical output lead connected to each of said two or more reservoir caps; and a source of electric power and circuitry for applying an electrical current through each of said two or more discrete reservoir caps, via said electrical input lead and said electrical output lead, in an amount effective to disintegrate said two or more reservoir caps. - View Dependent Claims (28, 29, 30, 31)
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Specification