Dynamic tumor diagnostic and treatment system

• US 7,606,405 B2
• Filed: 05/03/2006
• Issued: 10/20/2009
• Est. Priority Date: 08/05/2003
• Status: Active Grant

• Current Assignee: Imquant, LLC
• Original Assignee: Imquant, LLC
• Inventors: Payne, Thomas Edwin, Sawyer, Timothy E.
• Primary Examiner(s): Chawan; Sheela C
• Application Number:
  US11/417,080
• Publication Number:
  US 20070014454A1
• Time in Patent Office: 1,266 Days
• Field of Search: 382/118, 382/128, 382/131, 382/294, 382/132, 382/199, 378/98.9, 378/65, 378/205, 378/4, 378/207, 600/407, 600/427, 600/415, 600/425, 600/411, 600/426, 600/439, 600/431, 600/410, 600/436, 600/414, 600/1, 600/429, 600/443, 600/437, 600/401, 250/363.04, 250/363.03, 250/363.02, 250/252.1, 424/1.11, 424/1.65, 423/2, 423/510, 128/906, 540/145
• US Class Current: 382/128
• CPC Class Codes: A61B 2090/363 Use of fiducial points
• CPC Class Codes: A61B 6/506 for diagnosis of nerves
• CPC Class Codes: A61N 5/103 Treatment planning systems
• CPC Class Codes: A61N 5/1049 for verifying the position of the patient with respect to the radiation beam
• CPC Class Codes: G06T 2207/30068 Mammography; Breast
• CPC Class Codes: G06T 7/0012 Biomedical image inspection
• CPC Class Codes: Y10S 378/901 Computer tomography program or processor

Abstract

A workstation imports medical images that depict a tumor and provides tools that enable a physician to see the results of prior therapies, plan future therapies, predict the outcome of future therapies and control future therapies. The workstation processes the imported images to produce isonumeric images of the tumor that can be analyzed by an expert system that provides diagnostic and outcome information as well as suggestions for further testing and therapy.

Claims

1. A tumor analysis system which comprises:

means for importing an image of a tumor;

means for producing from the imported image an isonumeric image that depicts a contour indicative of locations in the imported image having a selected threshold value of a tumor parameter;

a case study storage for storing isonumeric images;

means for calculating changes in the tumor depicted in the imported image by comparing the isonumeric image produced from the imported image with previously produced isonumeric images stored in the case study storage and storing the changes in the case study storage; and

an expert system for analyzing the tumor using information stored in the case study storage.

2. The system as recited in claim 1 in which the expert system includes a rules knowledge base and an inference engine, and in which the inference engine is operable in response to information received from the rules knowledge base to examine information in the case study storage and produce information regarding one of diagnosis, testing and treatment of the tumor.

3. The system as recited in claim 1 which includes means for calculating tumor parameters from the isonumeric image and storing them in the case study storage.

4. The system as recited in claim 3 in which a sub-volume is identified in the isonumeric image and parameters related to the sub-volume are calculated and stored in the case study storage.

5. The system as recited in claim 4 in which the expert system separately analyzes the sub-volume and produces information regarding one of diagnosis, testing and treatment that is distinct from information regarding one of diagnosis, testing, and treatment of the tumor as a whole.

6. A tumor analysis system which comprises:

means for importing an image of a tumor;

means for calculating from this image values of parameters that measure the tumor;

a case study storage for storing the calculated parameters;

means for calculating changes that have occurred in tumor parameters based on parameters previously stored in the case study storage; and

an expert system for producing a target contour for further treatment of the tumor based on information in the case study storage.

7. The system as recited in claim 6 in which the expert system includes a rules knowledge base and an inference engine that receives information from the case study storage and information from the rules knowledge base.

8. The system as recited in claim 6 in which one of the calculated parameters is a sub-volume of the tumor and the target contour is limited to the sub-volume.

9. A method for analyzing a pathology, the steps comprising:

a) importing an image of the pathology;

b) producing an isonumeric image of the imported image that depicts a contour indicative of locations in the imported image having a selected threshold value of a pathology parameter;

c) storing the isonumeric image in a case study storage;

d) calculating parameters related to the pathology from the stored isonumeric image; and

e) analyzing the pathology with an expert system that examines parameters stored in the case study storage using rules stored in a rules knowledge base.

10. The method as recited in claim 9 in which step d) includes calculating changes in the pathology by comparing the stored isonumeric image with previously produced isonumeric images stored in the case study storage.

11. The method as recited in claim 9 in which step d) includes calculating parameters related to a sub-volume of the pathology depicted in the stored isonumeric image.

12. The method as recited in claim 11 in which step e) includes examining parameters related to the sub-volume and producing an indication based on the examination.