Electrode arrangement for nerve stimulation and methods of treating disorders

• US 7,610,103 B2
• Filed: 12/19/2005
• Issued: 10/27/2009
• Est. Priority Date: 12/19/2005
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Carbunaru, Rafael, Jaax, Kirsten N., Kuzma, Janusz A., Whitehurst, Todd Kevin
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Dinga; Roland
• Application Number:
  US11/311,502
• Publication Number:
  US 20070142889A1
• Time in Patent Office: 1,408 Days
• Field of Search: 607/39, 607/41, 607/45, 607/46, 607/116, 607/118, 607/138, 607/117
• US Class Current: 607/118
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0556 Cuff electrodes

Abstract

A stimulator arrangement for stimulating nerves or other tissue includes an electrode arrangement having a substrate and a plurality of electrodes disposed on the substrate. The substrate is configured and arranged to be in a curved state prior to implantation into the body and to flatten with exposure to the body after implantation. The stimulator arrangement may also include a stimulator unit coupled to the electrode arrangement. The stimulator unit may also be implantable.

Claims

1. A stimulator arrangement for a nerve in a body of a patient, comprising:

an electrode arrangement having

a substrate comprising an inner surface, the substrate comprising an arched portion and at least one relatively-flat stabilizing portion extending from, and abutting, each side of two opposing sides of the arched portion, wherein the inner surface of the arched portion is configured and arranged to receive the nerve upon implantation, wherein the arched portion is formed from a material configured and arranged to flatten the arched portion in response to exposure to the body after implantation such that the inner surface of the arched portion at least partially flattens the nerve, and

a plurality of electrodes disposed on the inner surface of the substrate.

2. The stimulator arrangement of claim 1, further comprising a stimulator unit coupled to the electrodes of the electrode arrangement.

3. The stimulator arrangement of claim 1, wherein the electrode arrangement further comprises a plurality of posts that extend from the substrate and into tissue of the body.

4. The stimulator arrangement of claim 3, wherein at least a portion of the electrodes are disposed on the plurality of posts.

5. The stimulator arrangement of claim 4, wherein all of the electrodes are disposed on the plurality of posts.

6. The stimulator arrangement of claim 4, wherein the electrodes disposed on the plurality of posts are disposed at tips of the posts.

7. The stimulator arrangement of claim 4, wherein at least two electrodes are disposed on each of at least a portion of the plurality of posts.

8. The stimulator arrangement of claim 4, wherein at least a portion of the electrodes disposed on the plurality of posts are disposed as rings around the posts.

9. The stimulator arrangement of claim 4, wherein at least a portion of the electrodes disposed on the plurality of posts are disposed on only one side of the posts.

10. The stimulator arrangement of claim 3, wherein the plurality of posts are configured and arranged to lie next to the substrate prior to implantation and to extend away from the substrate after implantation.

11. A nerve stimulator, comprising:

a stimulator unit;

an electrode arrangement for disposition adjacent the nerve, wherein the electrode arrangement comprises

a substrate comprising an inner surface, the substrate comprising an arched portion and at least one relatively-flat stabilizing portion extending from, and abutting, each side of two opposing sides of the arched portion, wherein the inner surface of the arched portion is configured and arranged to receive the nerve upon implantation, wherein the arched portion is formed from a material configured and arranged to flatten the arched portion in response to exposure to patient tissue after implantation such that the inner surface of the arched portion at least partially flattens the nerve, and

a plurality of electrodes disposed on the inner surface of the substrate; and

a lead coupling the stimulator unit to the electrodes of the electrode arrangement.

12. The nerve stimulator of claim 11, wherein the electrode arrangement further comprises a plurality of posts formed on the substrate.

13. The nerve stimulator of claim 12, wherein at least a portion of the electrodes are disposed on the plurality of posts.

14. The nerve stimulator of claim 11, wherein the nerve stimulator defines a lumen for providing a drug to tissue adjacent the electrode arrangement.