Acoustic beam forming in phased arrays including large numbers of transducer elements

• US 7,611,462 B2
• Filed: 05/22/2003
• Issued: 11/03/2009
• Est. Priority Date: 05/22/2003
• Status: Active Grant

• Current Assignee: InSightec Ltd.
• Original Assignee: Insightec-Image-Guided Treatment Limited (InSightec Ltd.)
• Inventors: Ezion, Avner, Vitek, Shuki, Vortman, Kobi
• Primary Examiner(s): Le; Long V
• Assistant Examiner(s): Cattungal; Sanjay
• Application Number:
  US10/443,549
• Publication Number:
  US 20040236253A1
• Time in Patent Office: 2,357 Days
• Field of Search: 600/407, 600/408, 600437-461, 601 2- 4, 367/7, 367/11, 367/138, 342/374
• US Class Current: 600/437
• CPC Class Codes: A61N 2007/0065 Concave transducers
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 2007/0091 with moving parts, e.g. transducers, lenses, reflectors
• CPC Class Codes: A61N 2007/0095 by modifying an excitation signal
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: G10K 11/346 using phase variation

Abstract

A focused ultrasound system includes a transducer array, a controller for providing drive signals to the transducer array, and a switch. The transducer array includes a plurality of “n” transducer elements, and the controller includes a plurality of “m” output channels providing sets of drive signals having respective phase shift values, “m” being less than “n.” The switch is coupled to the output channels of the controller and to the transducer elements, and is configured for connecting the output channels to respective transducer elements. The controller may assign the transducer elements to respective output channels based upon a size and/or shape of a desired focal zone within the target region, to steer or otherwise move a location of the focal zone, and/or to compensate for tissue aberrations caused by tissue between the transducer array and the focal zone, geometric tolerances and/or impedance variations of the transducer elements.

Claims

1. A system for focusing acoustic energy towards a target region, comprising:

a transducer array comprising a plurality of “

n”

transducer elements;

a controller for providing drive signals to the transducer array, the controller comprising a plurality of “

m”

output channels providing sets of drive signals having respective phase shift values, “

m”

being less than “

n,”

wherein the controller is configured for assigning phase shift values to each of the transducer elements at least partially based upon an analysis of an acoustic path extending from each of the transducer elements to a desired focal zone within the target region; and

a switch coupled to the output channels of the controller and to the transducer elements of the transducer array, the switch configured for connecting output channels to respective transducer elements in order to provide respective sets of drive signals to the respective transducer elements, whereby acoustic energy transmitted by the transducer array may be focused in a desired manner.

2. The system of claim 1, wherein the switch comprises a cross-point matrix or a multistage interconnection network (MIN).

3. The system of claim 1, wherein the switch comprises a plurality of “

m”

inputs coupled to the output channels of the controller, a plurality of “

n”

outputs coupled to the transducer elements, and a plurality of switching elements for connecting each of the inputs to one or more of the outputs.

4. The system of claim 1, wherein the switch is configured for coupling each output channel to more than one of the transducer elements.

5. The system of claim 1, further comprising an imaging apparatus for performing the acoustic path analysis, the controller coupled to the imaging apparatus for obtaining data related to the acoustic path analysis from the imaging apparatus.

6. The system of claim 1, wherein the controller is coupled to the switch for configuring the switch in order to connect the output channels to the respective transducer elements.

7. The system of claim 1, wherein the controller is configured for assigning each of the transducer elements to a respective output channel based upon one or more parameters related to a course of treatment of a target tissue region using the transducer array.

8. The system of claim 1, wherein the controller is configured for focusing the acoustic energy from the transducer array during a series of sonications into a target region, the switch being configurable before each sonication for focusing the acoustic energy into the target region to treat tissue within the target region.

9. The system of claim 1, wherein controller is configured for assigning the transducer elements to respective output channels via the switch in order to steer a focal zone within the target region in a desired manner.

10. A system for focusing acoustic energy towards a target region, comprising:

a transducer array comprising a plurality of “

n”

transducer elements;

a controller for providing drive signals to the transducer array, the controller comprising a plurality of “

m”

output channels providing sets of drive signals having respective phase shift values, “

m”

being less than “

n,”

wherein the controller is configured for assigning the transducer elements to respective output channels based upon at least one of tissue aberrations caused by tissue between the transducer array and the focal zone, geometric tolerances of the transducer array, or impedance variations between the transducer elements; and

a switch coupled to the output channels of the controller and to the transducer elements of the transducer array, the switch configured for connecting output channels to respective transducer elements in order to provide respective sets of drive signals to the respective transducer elements, whereby acoustic energy transmitted by the transducer array may be focused in a desired manner.

11. A method for delivering acoustic energy from a transducer array comprising a plurality of “

n”

transducer elements, the method comprising;

assigning one of “

m”

phase shift values to each of the transducer elements, “

m”

being less than “

n;

” and

delivering “

m”

sets of drive signals to the transducer array, each set of drive signals comprising a respective phase shift value selected from the “

m”

phase shift values, wherein the phase shift values are assigned to the transducer elements at least partially based on an analysis of an acoustic path from each of the transducer elements to the target region; and

connecting the sets of drive signals to respective transducer elements based upon the phase shift values assigned to the respective transducer elements, whereby acoustic energy transmitted by the transducer elements may be focused in a desired manner towards a target region.

12. The method of claim 11, wherein connections between the sets of drive signals and respective transducer elements are reconfigured dynamically while acoustic energy is transmitted by the transducer elements.

13. The method of claim 11, wherein the phase shift value assigned to each of the transducer elements is compared to phase shift values of the sets of drive signals, and wherein each transducer element is assigned to a set of drive signals that has a phase shift value that approximates the phase shift value assigned to the respective transducer element.

14. The method of claim 11, wherein a table is generated during the acoustic path analysis that identifies the sets of drive signals assigned to each of the transducer elements, and wherein the table is used at least partially to configure a switch coupled to the transducer elements to connect the transducer elements to respective sets of drive signals.

15. A method for delivering acoustic energy from a transducer array comprising a plurality of “

n”

transducer elements, the method comprising;

assigning one of “

m”

phase shift values to each of the transducer elements, “

m”

being less than “

n;

”

, wherein the phase shift values are assigned to the transducer elements at least partially based on analyzing an acoustic path from each of the transducer elements to the target region,

delivering “

m”

sets of drive signals to the transducer array, each set of drive signals comprising a respective phase shift value selected from the “

m”

phase shift values; and

connecting the sets of drive signals to respective transducer elements based upon the phase shift values assigned to the respective transducer elements, whereby acoustic energy transmitted by the transducer elements may be focused in a desired manner towards a target region, wherein the transducer array is disposed adjacent to a body, and wherein the transducer elements transmit acoustic energy into the body towards a focal zone within the target region when connected to the sets of drive signals.

16. The method of claim 15, wherein the acoustic energy is transmitted for sufficient time to ablate tissue within the target region.

17. The method of claim 15, wherein the phase shift values are assigned to the transducer elements at least partially to steer the focal zone within the target region relative to a central axis of the transducer array.

18. The method of claim 15, wherein the phase shift values are assigned to the transducer elements in order to focus the acoustic energy at multiple focal zones within the target tissue region.

19. A method for delivering acoustic energy from a transducer array comprising a plurality of “

n”

transducer elements to a target region, the method comprising;

providing “

m”

sets of drive signals, each set of drive signals comprising a respective phase shift value selected from “

m”

phase shift values, “

m”

being less than “

n;

”

analyzing an acoustic path from each of the transducer elements to the target region;

determining a phase shift value for each of the transducer elements based upon the acoustic path analysis;

connecting a first set of the drive signals to a first plurality of the transducer elements; and

connecting a second set of the drive signals to a second plurality of the transducer elements, wherein each of the “

m”

sets of drive signals is connected to a plurality of the “

n”

transducer elements, each of the transducer elements is connected to one of the sets of drive signals, and connecting each of the transducer elements to one of the sets of drive signals is at least partially based upon the phase shift values of the respective transducer elements and the sets of drive signals, whereby acoustic energy is transmitted by the first and second plurality of transducer elements and focused in a desired manner into the target region.

20. The method of claim 19, wherein desired phase shift values are assigned to each of the transducer elements based upon at least one of a size, shape, and location of a focal zone within the target region, and wherein the desired phase shift values are combined with the phase shift values determined based upon the acoustic path analysis.

21. The method of claim 20, wherein the combined phase shift values for the transducer elements are compared to the phase shift values of the sets of drive signals, and wherein the transducer elements are assigned to respective sets of drive signals having phase shift values that approximate the combined phase shift values of the respective transducer elements.

22. The method of claim 19, wherein the acoustic energy transmitted by the first plurality of transducer elements is focused at a different location within the target region than the acoustic energy transmitted by the second plurality of transducer elements.

23. A method for delivering acoustic energy from a transducer array comprising a plurality of “

n”

transducer elements to a target region, the method comprising;

providing “

m”

sets of drive signals, each set of drive signals comprising a respective phase shift value selected from “

m”

phase shift values, “

m”

being less than “

n;

”

connecting a first set of the drive signals to a first plurality of the transducer elements; and

connecting a second set of the drive signals to a second plurality of the transducer elements, whereby acoustic energy is transmitted by the first and second plurality of transducer elements and focused in a desired manner into the target region,

wherein the first and second plurality of transducer elements are connected to first and second sets of drive signals based upon at least one of an analysis of an acoustic path extending from each of the transducer elements to a desired focal zone within the target region, tissue aberrations caused by tissue between the transducer array and the focal zone, geometric tolerances of the transducer array, or impedance variations between the transducer elements.

24. The method of claim 23, wherein the acoustic energy transmitted by the first plurality of transducer elements is focused at a different location within the target region than the acoustic energy transmitted by the second plurality of transducer elements.