Assay device
First Claim
1. An assay device for quantification or detection of the presence or absence of an analyte in a liquid sample, comprising:
- (a) a first sub-assembly;
(b) a capillary chamber;
(c) a sample receiving zone in the first sub-assembly permanently fixed in relation to and in contact with the capillary chamber;
(d) a second sub-assembly comprising a holder to accommodate an absorbent pad; and
(e) wherein the first and second sub-assemblies are arranged in movable sliding relation relative to each other such that in a first position there is a gap between the holder of the second sub-assembly and the capillary chamber and in a second position the holder of the second sub-assembly is in contact with the capillary chamber, and wherein the capillary chamber is between said sample receiving zone and said holder.
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Accused Products
Abstract
The invention provides an assay device for quantification or detection of the presence or absence of an analyte in a liquid sample, comprising a molding (1) permanently or removably attached to a substantially planar plate (2) such that a part of said molding forms a capillary chamber (3) between said plate and the said molding, the device further comprising a chamber (5) into which a test sample and/or reagent can be introduced and further comprising a chamber (7) capable of accommodating an absorbent pad, wherein the said chamber into which a test sample and said chamber capable of holding an absorbent pad are in lateral flow contact via the said capillary chamber (3).
22 Citations
19 Claims
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1. An assay device for quantification or detection of the presence or absence of an analyte in a liquid sample, comprising:
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(a) a first sub-assembly; (b) a capillary chamber; (c) a sample receiving zone in the first sub-assembly permanently fixed in relation to and in contact with the capillary chamber; (d) a second sub-assembly comprising a holder to accommodate an absorbent pad; and (e) wherein the first and second sub-assemblies are arranged in movable sliding relation relative to each other such that in a first position there is a gap between the holder of the second sub-assembly and the capillary chamber and in a second position the holder of the second sub-assembly is in contact with the capillary chamber, and wherein the capillary chamber is between said sample receiving zone and said holder. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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- 15. A method of forming an assay device comprising permanently or removably attaching a planar plate to an assembly such that a first sub-assembly of said assembly forms a planar capillary chamber between said plate and said assembly and participates in forming a sample receiving zone on one side of said capillary chamber, such that said sample receiving zone and said capillary chamber are in permanent fixed contact, the method further comprising slidingly attaching a second sub-assembly to the first sub-assembly, the second sub-assembly comprising a holder to accommodate an absorbent pad, whereby the holder of the second sub-assembly is moveable relative to the capillary chamber such that said holder can be moved in and out of contact with a second side of said capillary chamber.
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18. A method of quantifying or detecting the presence or absence of an analyte in a liquid sample, comprising:
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(a) applying the liquid sample to a device comprising; 1) a first sub-assembly; 2) a capillary chamber; 3) a sample receiving zone in the first sub-assembly in permanent contact with a first side of the capillary chamber; 4) a second sub-assembly comprising a holder to accommodate an absorbent pad; and 5) wherein the first and second sub-assemblies are arranged in sliding relation to each other such that in a first position there is a gap between the holder of the second sub-assembly and the capillary chamber and a second position in which the holder of the second sub-assembly is in contact with a second side of the capillary chamber; wherein the device is in the first position when the liquid sample is applied to the device; and (b) moving the second sub-assembly to the second position. - View Dependent Claims (19)
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Specification