Heterocyclic compounds as inhibitors of beta-lactamases
First Claim
1. A pharmaceutical composition comprising a bacterial β
- -lactamase inhibitory amount of a compound, or a pharmaceutically acceptable salt thereof, of formula (I);
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Abstract
This invention discloses and claims methods for inhibiting bacterial β-lactamases and treating bacterial infections by inhibiting bacterial β-lactamases in man or an animal comprising administering a therapeutically effective amount to said man or said animal of a compound, or pharmaceutically acceptable salt thereof, of formula (I) either alone or in combination with a β-lactamine antibiotic wherein said combination can be administered separately, together or spaced out over time. Pharmaceutical compositions comprising a compound of formula (I), or a combination of a compound of formula (I) and a therapeutically effective amount of a β-lactamine antibiotic, and a pharmaceutically acceptable carrier are also disclosed and claimed.
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Citations
16 Claims
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1. A pharmaceutical composition comprising a bacterial β
- -lactamase inhibitory amount of a compound, or a pharmaceutically acceptable salt thereof, of formula (I);
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
- -lactamase inhibitory amount of a compound, or a pharmaceutically acceptable salt thereof, of formula (I);
Specification