Implantable cardiac stimulation device, system and method which provides an electrogram signal facilitating measurement of slow-changing electrogram features

• US 7,613,508 B2
• Filed: 10/12/2007
• Issued: 11/03/2009
• Est. Priority Date: 09/25/2001
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Boileau, Peter, Gill, Jong, Bornzin, Gene A.
• Primary Examiner(s): Getzow; Scott M
• Application Number:
  US11/871,873
• Publication Number:
  US 20080033499A1
• Time in Patent Office: 753 Days
• Field of Search: 607 4- 28, 600508-522
• US Class Current: 600/509
• CPC Class Codes: A61B 5/283 Invasive
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371

Abstract

An implantable cardiac system including an implantable cardiac stimulation device provides a heart activity signal of a heart facilitating measurement of slowly changing electrogram features. The system comprises at least one implantable electrode arrangement that senses cardiac electrical activity and provides an intracardiac electrogram signal, a first high pass filter that filters the electrogram and an equalizer that filters the filtered electrogram signal. The equalizer has a transfer function that is non-decreasing for frequencies up to a lower frequency breakpoint that is less than the upper frequency breakpoint, decreasing for frequencies between the lower frequency breakpoint and the upper frequency breakpoint, and generally flat for frequencies above the upper frequency breakpoint through a bandpass region of interest.

Claims

1. An implantable cardiac system including an implantable cardiac stimulation device, the system providing a heart activity signal of a heart facilitating measurement of slowly changing electrogram features, the system comprising:

at least one implantable electrode arrangement that senses cardiac electrical activity and provides an intracardiac electrogram signal;

a first high-pass filter with a cutoff frequency at an upper frequency breakpoint that filters the intracardiac electrogram signal, and

an equalizer that filters the filtered intracardiac electrogram signal, the equalizer having a transfer function derived by multiplying a reciprocal of the transfer function of the first high pass filter by a transfer function of a second high pass filter with a cutoff frequency at a lower frequency breakpoint, wherein the transfer function of the equalizer is non-decreasing for frequencies up to the lower frequency breakpoint.

2. The system of claim 1 wherein the implantable cardiac stimulation device includes a memory that stores the intracardiac electrogram signal prior to being filtered.

3. The system of claim 1 wherein the transfer function of the equalizer increases for frequencies up to the lower frequency breakpoint.

4. The system of claim 1 wherein the transfer function of the equalizer has a second order response from the lower frequency breakpoint to the upper frequency breakpoint.

5. The system of claim 1 wherein the upper frequency breakpoint is on the order of 1 Hertz.

6. The system of claim 1 wherein the lower frequency breakpoint is less than about 0.25 Hertz.

7. The system of claim 1 wherein the at least one electrode arrangement comprises an electrode adapted for implant in the right atrium of the heart.

8. The system of claim 1 wherein the at least one electrode arrangement comprises an electrode adapted for implant in, on or proximate to a ventricle of the heart.

9. The system of claim 1 wherein the at least one electrode arrangement comprises a first electrode adapted for implant in, on or proximate to an atrium of the heart and a second electrode adapted for implant in, on or proximate to a ventricle of the heart.

10. In an implantable cardiac system, a method of providing a heart activity signal of a heart which facilitates measurement of slowly changing electrogram features, the method comprising:

sensing cardiac electrical activity with at least one implanted electrode arrangement to provide an electrogram signal;

filtering the electrogram signal with a first high-pass filter with a cutoff frequency at an upper frequency breakpoint; and

filtering the filtered electrogram signal with a equalizer having a transfer function that is;

non-decreasing for frequencies up to a lower frequency breakpoint that is less than the upper frequency breakpoint, decreasing for frequencies between the lower frequency breakpoint and the upper frequency breakpoint, and generally flat for frequencies above the upper frequency breakpoint through a bandpass region of interest.

11. The method of claim 10 wherein the transfer function of the equalizer increases for frequencies up to the lower frequency breakpoint.

12. The method of claim 10 wherein the transfer function of the equalizer has a second order response from the lower frequency breakpoint to the upper frequency breakpoint.

13. The method of claim 10 wherein filtering the filtered electrogram comprises twice filtering the intracardiac signal with the equalizer to obtain a second order response.

14. An implantable cardiac system including an implantable cardiac stimulation device, the system providing a heart activity signal of a heart facilitating measurement of slowly changing electrogram features, the system comprising:

at least one implantable electrode arrangement that senses cardiac electrical activity and provides an electrogram signal;

a first high-pass filter with a cutoff frequency at an upper frequency breakpoint that filters the electrogram signal, and

a plurality of serially arranged equalizers that filter the filtered electrogram signal, each equalizer having a transfer function derived as a function of a reciprocal of the transfer function of the first high pass filter and a transfer function of a second high pass filter with a cutoff frequency at a lower frequency breakpoint.

15. The system of claim 14 wherein the transfer function of at least one of the equalizers is non-decreasing for frequencies up to the lower frequency breakpoint.

16. The system of claim 14 wherein the transfer function of at least one of the equalizers increases for frequencies up to the lower frequency breakpoint.