Randomized stimulation of a gastrointestinal organ

• US 7,616,996 B2
• Filed: 09/01/2005
• Issued: 11/10/2009
• Est. Priority Date: 09/01/2005
• Status: Active Grant

• Current Assignee: IntraPace, Inc.
• Original Assignee: IntraPace, Inc.
• Inventors: Imran, Mir A.
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Dinga; Roland
• Application Number:
  US11/219,004
• Publication Number:
  US 20070049986A1
• Time in Patent Office: 1,531 Days
• Field of Search: 607/40, 607/41, 607/72, 607/73, 607/116, 607/133, 607/138, 600/29, 600/30
• US Class Current: 607/40
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control

Abstract

A device, system and method for stimulating a digestive organ is provided where the stimulation is randomized.

Claims

1. A method of randomly stimulating a digestive organ comprising the steps of:

providing a stimulator electrically coupled to the digestive organ;

randomly selecting an initial parameter for stimulation of the digestive organ at non-physiologic rates, wherein the step of selecting a parameter comprises generating a random number corresponding to a pre-selected stimulation parameter and determining the random stimulation parameter based on the random number;

delivering a stimulation signal comprising the parameter to the digestive organ;

sensing a response to the stimulation signal;

determining if the response is a desired response; and

randomly selecting a subsequent parameter if the response is not the desired response.

2. The method of claim 1 wherein the step of randomly selecting a parameter comprises pseudorandomly selecting a parameter.

3. The method of claim 2 wherein the step of randomly selecting a parameter comprises selecting a parameter from predetermined parameter windows.

4. The method of claim 1 wherein the step of selecting a parameter comprises selecting a first parameter from a first type of parameters and selecting a second parameter from a second type of parameters;

and

wherein the step of delivering a stimulation signal comprises delivering a stimulation signal comprising the first parameter and the second parameter to the digestive organ.

5. The method of claim 1 wherein the step of delivering the signal to the digestive organ comprises delivering the signal to a portion of the gastrointestinal tract.

6. The method of claim 5 wherein the step of delivering the signal to the gastrointestinal tract comprises delivering a signal to the stomach to create a sensation of satiety.

7. The method of claim 1 further comprising the step of:

wherein the step of providing a stimulator electrically coupled to the digestive organ comprises providing a stimulator electrically coupled to a plurality of sites at the digestive organ;

wherein the step of randomly selecting a parameter for stimulation of the digestive organ comprises randomly selecting an independent parameter for stimulation at each of the plurality of sites; and

wherein the step of delivering a stimulation signal comprising the parameter to the digestive organ comprises delivering a stimulation signal comprising an independent parameter to each of the plurality of sites wherein the each independent parameter at a site is independently selected from other of the independent parameters delivered to other of said plurality of sites.

8. The method of claim 1 wherein the random parameter is selected from the group consisting of pulse width, pulse amplitude, pulse repetition rate, burst frequency, burst repetition rate, pulses per burst, pulse shape and burst envelope.