Needle-less injector and method of fluid delivery

• US 7,618,393 B2
• Filed: 11/13/2006
• Issued: 11/17/2009
• Est. Priority Date: 05/03/2005
• Status: Active Grant

• Current Assignee: PharmaJet, Inc.
• Original Assignee: PharmaJet, Inc.
• Inventors: Bingham, John, Steinway, Robert
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): VU, QUYNH-NHU HOANG
• Application Number:
  US11/598,193
• Publication Number:
  US 20070118094A1
• Time in Patent Office: 1,100 Days
• Field of Search: 604/68, 604/131, 604/133, 604/134, 604/135, 604/137, 604/151, 604/152, 604/181, 604/187, 604/199
• US Class Current: 604/68
• CPC Class Codes: A61M 2005/208 Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
• CPC Class Codes: A61M 2205/6081 Colour codes
• CPC Class Codes: A61M 5/002 Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: A61M 5/3158 performed by axially moving actuator operated by user, e.g. an injection button
• CPC Class Codes: A61M 5/425 Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means

Abstract

A needle-less injector device for delivering a dose of fluid intradermally, subcutaneously or intramuscularly to an animal or human. The device includes an inner housing having opposed ends. A syringe is disposed in one end of the inner housing. The syringe includes a nozzle for delivering a dose of fluid held within the syringe. A plunger is movably disposed within the syringe. A spring powered hammer is movably disposed within the inner housing. The hammer cooperates with the plunger to drive the dose of medicament from the nozzle. An injection delivery spring for powering the hammer is positioned and compressed between the other end of the inner housing and the spring powered hammer. An outer housing slideably supports the inner housing. A skin tensioning spring is mounted between the inner housing and the outer housing, the skin tensioning spring biasing the nozzle of the syringe against the animal or human. A trigger mechanism is disposed in the outer housing, the trigger mechanism cooperating with the spring powered hammer to release the injection delivery spring, wherein the size of the injection delivery spring and the length of the hammer dictate the amount of dose delivered and whether the dose is delivered intradermally, subcutaneously or intramuscularly to an animal or human.

Claims

1. A needle-less injector device comprising:

an outer housing;

an inner housing having opposed first and second ends;

wherein the inner housing is within the outer housing, the inner housing being movable within the outer housing between a ready position and a firing position;

a syringe in the first end of the inner housing, the syringe including a nozzle for delivering a dose of fluid held within the syringe;

a plunger within the syringe;

a spring powered hammer within the inner housing, the hammer communicating with the plunger to drive the fluid from the nozzle;

an injection delivery spring located between the second end of the inner housing and the spring powered hammer;

an outer housing supporting the inner housing;

a tensioning spring mounted between the inner housing and the outer housing, and configured to provide force to the syringe such that a tip of the syringe pulls adjacent skin of a patient or animal taut when the inner housing is in a firing position; and

a trigger mechanism in the outer housing, the trigger mechanism cooperating with the hammer to release the injection delivery spring.

2. The device of claim 1, wherein the trigger mechanism moves in the outer housing between a cocked position and an unloaded position.

3. The device of claim 2, wherein the trigger mechanism includes a trigger in communication with the hammer, and wherein the injection delivery spring is compressed when the spring powered hammer is moved toward the second end of the inner housing.

4. The device of claim 1, wherein the injection delivery spring controls the depth of the delivery of the fluid into the skin.

5. The device of claim 1, wherein the hammer length determines the amount of fluid delivered.

6. The device of claim 1, wherein the syringe a polymer.

7. The device of claim 6, wherein the syringe comprises topas®

.

8. The device of claim 1, wherein the syringe comprises polypropylene.

9. The device of claim 1, wherein the plunger comprises a polycarbonate material.

10. The device of claim 1, wherein the syringe has a volume to contain a single dose of a medicament.

11. The device of claim 1, wherein the syringe has a volume to contain multiple doses of a medicament.

12. The device of claim 1, wherein the syringe has a volume to contain a dose of medicament within the range of 0.1 cc to 1 cc.

13. The device of claim 1, wherein the syringe is pre-filled with a dose of medicament.

14. A needle-less injector device comprising:

an outer housing;

an inner housing within the outer housing, the inner housing being movable within the outer housing between a ready position and a firing position, the inner housing having a leading and a trailing end, the leading end adapted for receiving a syringe that includes a nozzle for delivering a dose of medicament held therein, the inner housing having a hammer movable from a cocked position to an unloaded position;

an injection delivery spring within the inner housing for driving the hammer;

a plunger sealingly engaged with the syringe, the plunger movable by the hammer to dispense the dose of medicament from the syringe;

a tensioning spring between the inner housing and the outer housing, the tensioning spring biasing the leading end of the inner housing away from the outer housing, wherein the tensioning spring is configured to provide force to the syringe such that a tip of the syringe pulls adjacent skin of a patient or animal taut when the inner housing is in the firing position; and

a trigger in the outer housing, the trigger being operable through the outer housing when the inner housing is in the firing position, the trigger cooperating with the hammer to release the hammer from the cocked position only when the inner housing is in the firing position, wherein the device is configured to deliver a dose of medicament of about 0.1 cc.

15. The device of claim 14, wherein the injection delivery spring stiffness controls the depth of the delivery of the dose of medicament.

16. The device of claim 14, wherein the hammer length determines a size of a delivered dose of medicament.

17. The device of claim 14, wherein the syringe comprises a polymer.

18. The device of claim 17, wherein the syringe comprises topas®

.

19. The device of claim 14, wherein the syringe comprises polypropylene.

20. The device of claim 14, wherein the plunger comprises a polycarbonate material.

21. The device of claim 14, wherein the syringe has a volume to contain a single dose of a medicament.

22. A method comprising:

providing a syringe containing a predetermined dose of medicament, the syringe including a nozzle for delivering the medicament and a skin tensioner;

providing a needle-less injector device including an inner housing having a leading end and a trailing end, the leading end being adapted for receiving the syringe, the inner housing further having a hammer;

an injection delivery spring in the inner housing between the hammer and the trailing end of the inner housing for driving the hammer;

a plunger movably and sealingly located within the syringe, the plunger being driven by the hammer;

an outer housing for receiving the inner housing therein, the inner housing being movable within the hollow outer housing between a safe position and a firing position;

a trigger n the outer housing, and a tensioning spring between the inner housing and the outer housing, wherein the tensioning spring is configured to provide force to the syringe such that a tip of the syringe pulls adjacent skin of a patient or animal taut when the inner housing is in a firing position;

placing the nozzle of the syringe against the skin; and

pressing the trigger to release the hammer, wherein the hammer forces the plunger through the syringe to eject the medicament from the syringe through the nozzle into the skin.

23. The method of claim 22, wherein placing the nozzle of the syringe against the skin further comprises positioning the skin tensioner against the skin and pressing the tensioner against the skin by pushing the outer housing towards the skin tensioner causing the outer housing to move towards the leading end of the inner housing against the skin and against a force from the tensioning spring until the inner housing is in the firing position, wherein the force from the tensioning spring pulls the adjacent skin taut in front of the nozzle.

24. The method of claim 22, wherein the dose of medicament has a volume within the range of 0.1 cc to 1 cc.

25. The method of claim 22, wherein syringe contains a multi-dose of the medicament.

26. The method of claim 22, wherein the syringe comprises a polymer.

27. The method of claim 26, wherein the syringe comprises topas®

.

28. The method of claim 22, wherein the syringe comprises polypropylene.

29. The method of claim 22, wherein the injection delivery spring controls the depth of the injection.

30. The method of claim 22, wherein providing the needle/less injection device further comprises a hammer, wherein the hammer length controls the amount of medicament driven from the syringe by the plunger.