Method and apparatus for tissue connection

• US 7,618,449 B2
• Filed: 09/01/2006
• Issued: 11/17/2009
• Est. Priority Date: 06/12/2002
• Status: Expired due to Fees

• Current Assignee: Mitral Interventions Incorporated
• Original Assignee: Mitral Interventions Incorporated
• Inventors: Razavi, Mahmood K., Tremulis, William S.
• Primary Examiner(s): GHERBI, SUZETTE JAIME J
• Application Number:
  US11/515,390
• Publication Number:
  US 20070173931A1
• Time in Patent Office: 1,173 Days
• Field of Search: 623/2.36, 623/1.11, 606/151, 604/500
• US Class Current: 623/2.11
• CPC Class Codes: A61B 17/0401 Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2017/00411 actuated by application of energy from an energy source outside the body
• CPC Class Codes: A61B 2017/00783 Valvuloplasty
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/0409 Instruments for applying suture anchors for applying suture clamps, clips or locks A61B2017/0488
• CPC Class Codes: A61B 2017/0417 T-fasteners
• CPC Class Codes: A61B 2017/044 with a threaded shaft, e.g. screws
• CPC Class Codes: A61B 2017/0441 the shaft being a rigid coil or spiral
• CPC Class Codes: A61B 2017/0464 for soft tissue
• CPC Class Codes: A61B 2017/349 Trocar with thread on outside
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus
• CPC Class Codes: A61F 2/2457 Chordae tendineae prostheses
• CPC Class Codes: A61F 2/2463 Implants forming part of the valve leaflets
• CPC Class Codes: A61F 2/2487 Devices within the heart chamber, e.g. splints
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section

Abstract

A tissue connecting device is provided. The device comprise an elongate delivery device having a lumen, a proximal end, and a distal end. The distal end is configured to engage tissue and advance said device into tissue. At least one anchor deliverable through a lumen of the elongate delivery device. The distal end of the device may be designed to engage tissue upon rotation of the device about its longitudinal axis.

Claims

1. A delivery system, comprising:

an elongated carrier;

a plurality of anchors configured to engage tissue, the plurality of anchors including a distal anchor, one or more intermediate anchors and a proximal anchor releasably carried within the elongated carrier and deliverable by the elongated carrier to a target tissue area;

a suture having a distal end secured to the distal anchor and slidably engaged with the one or more intermediate anchors and the proximal anchor, wherein, when tension is applied to the suture the target tissue area is constricted; and

a clamp slidably engaged with the suture and proximal to the proximal anchor, the clamp comprising a clamping region and a cutting region and configured to be advanced distally toward the proximal anchor and crimped, wherein the suture is clamped and cut under the tension.

2. A delivery system, comprising:

an elongated carrier;

a plurality of anchors configured to engage tissue, the plurality of anchors releasably carried within the elongated carrier and deliverable by the elongated carrier to selected tissue sites in a target tissue area;

a suture slidably engaged with the plurality of anchors, wherein when tension is applied to both ends of the suture, the target tissue area is constricted; and

a clamp slidably engaged with the suture and configured to be advanced distally using both ends of the suture and crimped, wherein the suture is clamped and cut under the tension.

3. The device of claim 2, wherein the elongated carrier comprises a catheter.

4. The device of claim 2, wherein the elongated carrier is insertable from a minimally invasive surgical entry.

5. The device of claim 2, wherein the anchors are self-positioning and self-securing anchors.

6. The device of claim 2, further comprising a clamp slidably engaged with the first segment and the third segment of the line and proximal to the plurality of anchors, the clamp comprising a clamping region and a cutting region, wherein the clamp is configured to be advanced distally toward the plurality of anchors and crimped, wherein the line is clamped and cut under the tension.

7. A tissue anchoring system, comprising:

an elongated carrier having a proximal end, a distal end and a lumen;

a plurality of anchors releasably carried by the elongated carrier;

a plurality of sutures threaded through the lumen of the elongated carrier, each suture having a distal end secured to one of the plurality of anchors,

wherein the anchors are configured to engage tissue sites in a target area of tissue;

a clamp slidably engaged with one of the plurality of sutures and proximal to the target area of tissue, clamp comprising a clamping region and a cutting region and configured to be advanced distally toward the target area of tissue and crimped, wherein each suture is clamped and cut.

8. The system of claim 7, wherein the plurality of sutures is selected from at least one of a suture material, a Teflon strip, a band, a filament, a wire and a strap.

9. The system of claim 7, further comprising:

a stabilization device configured to capture and immobilize an anatomical annulus.

10. The system of claim 9, wherein the stabilization device comprises a pair of rings configured to clamp opposed faces of the anatomical annulus.

11. The system of claim 10, wherein the anatomical annulus comprises a heart valve annulus.