Method and apparatus for drug product tracking using encoded optical identification elements

• US 7,619,819 B2
• Filed: 07/21/2005
• Issued: 11/17/2009
• Est. Priority Date: 08/20/2002
• Status: Active Grant

• Current Assignee: Illumina Incorporated
• Original Assignee: Illumina Incorporated
• Inventors: Pinto, Joseph, Kersey, Alan, Fournier, David, Putnam, Martin A., Moon, John A.
• Primary Examiner(s): Lavarias; Arnel C
• Application Number:
  US11/187,262
• Publication Number:
  US 20060028727A1
• Time in Patent Office: 1,580 Days
• Field of Search: None
• US Class Current: 359/569
• CPC Class Codes: G03H 1/0011 for security or authentication holograms on information-bearing cards B42D25/328; testing papers with holograms G07D7/0032
• CPC Class Codes: G03H 2001/0016 Covert holograms or holobjects requiring additional knowledge to be perceived, e.g. holobject reconstructed only under IR illumination
• CPC Class Codes: G06K 19/06009 with optically detectable marking G06K19/063, G06K19/08 take precedence
• CPC Class Codes: G06K 19/16 the marking being a hologram or diffraction grating
• CPC Class Codes: G06K 2019/0629 Holographic, diffractive or retroreflective recording
• CPC Class Codes: G07D 7/0032 using holograms
• CPC Class Codes: G07D 7/128 Viewing devices

Abstract

A method and apparatus for drug product tracking (or other pharmaceutical, health care or cosmetics products, and/or the packages or containers they are supplied with) using diffraction grating-based encoded optical identification elements includes an optical substrate having at least one diffraction grating disposed therein. The encoded element may be used to label any desired item, such as drugs or medicines, or other pharmaceutical or health care products or cosmetics. The label may be used for many different purposes, such as for sorting, tracking, identification, verification, authentication, anti-theft/anti-counterfeit, security/anti-terrorism, or for other purposes.

Claims

1. An optical identification element for identifying a drug, comprising:

an optical substrate;

at least a portion of said substrate having at least one diffraction grating embedded therein or thereon;

said grating having a resultant refractive index variation at a grating location;

said grating providing an output optical signal indicative of a code when illuminated by an incident light signal; and

the element being at least partially disposed on or within said drug; and

wherein said grating comprises a plurality of gratings having numerous different angular or rotational positions on or within the substrate.

2. The element of claim 1, wherein said refractive index variation comprises at least one refractive index pitch superimposed at said grating location.

3. The element of claim 1, wherein said refractive index variation comprises a plurality of refractive index pitches superimposed at said grating location.

4. The element of claim 1, wherein said code comprises a plurality of bits, each bit having a corresponding spatial location and each bit in said code having a value related to an intensity of said output optical signal at the spatial location of each bit.

5. The element of claim 1 wherein at least a portion of said substrate has a 3-D shape selected from the group:

cylinder, sphere, a cube, a pyramid.

6. The element of claim 1 wherein said substrate comprises a particle, filament, thread or bead.

7. The element of claim 1, wherein said drug is a manufactured drug product.

8. The element of claim 7 wherein said manufactured drug product comprises at least one of a pharmaceutical product, a medical product, a health care product, a cosmetics product, a pill, a capsule, a liquid medicine, and a powdered medicine or packages or containers that are supplied therewith.

9. The element of claim 7, wherein the manufactured drug product supports or holds the element in a fixed position.

10. The element of claim 1 wherein said code comprises an encrypted code.

11. The element of claim 1, wherein said substrate comprises one or more of the following:

a film, an adhesive film, a shrink wrap film, a label, and a security label.

12. The element of claim 1, wherein said gratings comprise a same code.

13. The element of claim 1, wherein at least two of said gratings intersect each other.

14. The element of claim 1, wherein said plurality of gratings intersect each other at a common central point.

15. An optical identification element for identifying a drug, comprising:

an optical substrate;

at least a portion of said substrate being made of a substantially single material and having at least one diffraction grating embedded therein or thereon;

said grating having a resultant refractive index variation within said single material at a grating location;

said grating providing an output optical signal indicative of a code when illuminated by an incident light signal propagating in free space; and

the element being at least partially disposed on or within said drug; and

wherein said grating comprises a plurality of gratings having a same code written therein at numerous different angular or rotational positions on or within the substrate.

16. A method of reading a code in an optical identification element that is disposed on or within a manufactured drug product, the method comprising:

providing a manufactured drug product having a plurality of optical identification elements disposed therein or thereon, each of said elements including a diffraction grating having a resultant refractive index variation at a grating location indicative of a code, at least two of said elements in or on said manufactured drug product having different orientations so that said gratings are at different angular or rotational positions within or on said manufactured drug product;

illuminating said manufactured drug product with incident light, said grating of at least one element providing an output light signal indicative of the code; and

reading said output light signal and detecting the code therefrom.

17. The method of claim 16, wherein said refractive index variation comprises a plurality of refractive index pitches superimposed at said grating location.

18. The method of claim 16 wherein said elements are randomly distributed on or within said manufactured drug product.

19. The method of claim 16 wherein said gratings comprise a same code.

20. The method of claim 16, wherein said code comprises a plurality of bits, each bit having a corresponding spatial location and each bit in said code having a value related to an intensity of said output optical signal at the spatial location of each bit.

21. The method of claim 16, wherein the illuminating said manufactured drug product includes illuminating at least one element with the incident light.

22. The method of claim 16, wherein the manufactured drug product comprises a large pill, a small pill, a capsule, a liquid medicine, or a powdered medicine.

23. A method for labeling a manufactured drug product, comprising:

obtaining an optical identification element having at least one diffraction grating, the grating having a resultant refractive index variation at a grating location;

the grating providing an output optical signal when illuminated by an incident light signal;

the optical output signal being indicative of a code; and

disposing the element at least partially on or within the manufactured drug product, wherein said grating is a plurality of gratings having different angular or rotational positions within or on said manufactured drug product.

24. The method of claim 23, wherein the manufactured drug product comprises a large pill, a small pill, a capsule, a liquid medicine, or a powdered medicine.

25. The method of claim 23, wherein said refractive index variation comprises a plurality of refractive index pitches superimposed at said grating location.

26. The method of claim 23, wherein said code comprises a plurality of bits, each bit having a corresponding spatial location and each bit in said code having a value related to an intensity of said output optical signal at the spatial location of each bit.

27. A manufactured drug product comprising:

a membrane that surrounds a medical substance;

at least a portion of said membrane having a diffraction grating embedded therein or thereon;

said grating having a resultant refractive index variation at a grating location; and

said grating providing an output optical signal indicative of a code when illuminated by an incident light signal; and

wherein said grating comprises a plurality of gratings at numerous different angular or rotational positions on or within the membrane.

28. The drug product of claim 27, wherein said plurality of gratings comprise a same code.

29. The drug product of claim 27, wherein at least two of said gratings intersect each other.

30. The drug product of claim 27, wherein said code comprises a plurality of bits, each bit having a corresponding spatial location and each bit in said code having a value related to an intensity of said output optical signal at the spatial location of each bit.

31. The drug product of claim 27, wherein the code comprises information for identifying or tracking the manufactured drug product.

32. The drug product of claim 27, wherein the medical substance is one of a liquid medicine or a powdered medicine.

33. The drug product of claim 27, wherein the membrane is one of a coating or a casing.

34. The drug product of claim 27, wherein the membrane comprises an outer surface of the manufactured drug product, the gratings being located on said outer surface.