System and method for providing a breathing gas

• US 7,621,270 B2
• Filed: 06/20/2005
• Issued: 11/24/2009
• Est. Priority Date: 06/23/2003
• Status: Expired due to Fees

• Current Assignee: Invacare Corporation
• Original Assignee: Invacare Corporation
• Inventors: Flolid, Gregory William, Morris, Make, Curran, Neal Joseph
• Primary Examiner(s): Douglas; Steven O
• Application Number:
  US11/157,089
• Publication Number:
  US 20050268913A1
• Time in Patent Office: 1,618 Days
• Field of Search: 128/204.18, 128/204.21, 128/204.23, 128/205.23, 128/205.24, 128/205.18, 128/200.24, 128/204.22
• US Class Current: 128/204.23
• CPC Class Codes: A61M 16/00 Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes stimulating the respiratory movement by mechanical, pneumatic or electrical means, iron lungs combined with gas breathing means A61H31/00
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/026 specially adapted for predicting, e.g. for determining an information representative of a flow limitation during a ventilation cycle by using a root square technique or a regression analysis
• CPC Class Codes: A61M 16/107 in the inspiratory path
• CPC Class Codes: A61M 16/204 used for inhalation control
• CPC Class Codes: A61M 16/205 used for exhalation control
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor

Abstract

Systems and methods for providing a breathing gas are provided. In one embodiment, the method includes sensing a sensed parameter associated with delivery of the breathing gas, changing a control parameter associated with a flow/pressure control element in response to a difference between the sensed parameter and a first predetermined sensed parameter value during a first portion of a breathing cycle, determining a transition from the first portion to a second portion of the breathing cycle based at least in part on the changing control parameter, changing the control parameter to cause a first change in the sensed parameter during the second portion of the breathing cycle based at least in part on the determined transition, and changing the control parameter to cause a second change in the sensed parameter during a third portion of the breathing cycle based at least in part on the first predetermined sensed parameter value.

Claims

1. A method of providing a breathing gas comprising:

a) sensing a sensed parameter associated with delivery of the breathing gas;

b) changing a control parameter associated with a flow/pressure control element in response to a difference between the sensed parameter and a first predetermined sensed parameter value during an inhalation state of a breathing cycle;

c) determining a transition from the inhalation state to an exhalation state of the breathing cycle based at least in part on the changing control parameter;

d) changing the control parameter to cause a first change in the sensed parameter during an unload portion of the exhalation state based at least in part on the determined transition; and

e) changing the control parameter to cause a second change in the sensed parameter during a load portion of the exhalation state based at least in part on the first predetermined sensed parameter value.

2. The method of claim 1 wherein the sensed parameter is breathing gas pressure, breathing gas flow, breathing gas temperature, or breathing gas composition.

3. The method of claim 1 wherein the flow/pressure control element includes a variable position valve and the control parameter includes a valve step position.

4. The method of claim 1 wherein the flow/pressure control element includes a variable speed blower and the control parameter includes a blower speed.

5. The method of claim 1 wherein the determining in c) comprises determining an average valve step position.

6. The method of claim 1 wherein the determining in c) comprises identifying an instantaneous valve step position.

7. The method of claim 1 wherein the determining in c) comprises determining a peak valve step position.

8. The method of claim 7 wherein determining the peak valve step position comprises identifying a highest valve step position between a present valve step position and one or more previous valve step positions and if the highest valve step position does not change for a predetermined peak valve step time, identifying the highest valve step position as the peak valve step position.

9. The method of claim 1 wherein the determining in c) is based at least in part on a predetermined percentage threshold value.

10. The method of claim 1 wherein the changing in d) comprises determining an inhale time associated with the inhalation state.

11. The method of claim 10 wherein the changing in d) comprises determining an exhale time associated with the unload portion of the exhalation state and based at least in part on the determined inhale time.

12. The method of claim 11 wherein the duration of the unload portion of the exhalation state is based at least in part on the exhale time.

13. The method of claim 11 wherein the exhale time is based at least in part on a predetermined exhale time factor.

14. The method of claim 1 wherein the changing in d) is based at least in part on an unloading function.

15. The method of claim 1 wherein the changing in d) is based at least in part on a second predetermined sensed parameter value.

16. The method of claim 1 wherein the changing in d) comprises determining a peak valve step position.

17. The method of claim 1 wherein the changing in e) is based at least in part on a loading function.

18. A method of providing a breathing gas comprising:

a) sensing a breathing gas pressure associated with delivery of the breathing gas;

b) detecting a start of an inhalation state of a breathing cycle;

c) changing a valve step position associated with a variable position valve in response to a difference between the sensed breathing gas pressure and a first predetermined breathing gas pressure value during the inhalation state;

d) determining a transition from the inhalation state to an exhalation state of the breathing cycle based at least in part on the changing valve step position;

e) changing the valve step position to cause a first change in the breathing gas pressure during an unload portion of the exhalation state based at least in part on the determined transition; and

f) changing the valve step position to cause a second change in the breathing gas pressure during a load portion of the exhalation state based at least in part on the first predetermined breathing gas pressure value.

19. The method of claim 18 wherein the detecting in b) comprises:

g) determining an average valve step position;

h) integrating a difference between an instantaneous valve step position and the average valve step position over a predetermined integration time to produce a summation; and

i) identifying the start of the inhalation state after the summation is greater than a predetermined start of inhalation threshold value.

20. The method of claim 18 wherein the determining in d) comprises:

g) calculating a first transition variable based at least in part on an instantaneous valve step position;

h) calculating a second transition variable based at least in part on a peak valve step position; and

i) identifying the transition from the inhalation state to the exhalation state after the first transition variable is less than or equal to the second transition variable.

21. The method of claim 20 wherein the calculating in g) comprises:

j) determining an average valve step position;

k) identifying the instantaneous valve step position; and

l) calculating the first transition variable by subtracting the average valve step position from the instantaneous valve step position.

22. The method of claim 20 wherein the calculating in h) comprises:

j) determining an average valve step position;

k) determining a peak valve step position for the inhalation state; and

l) calculating the second transition variable by multiplying a difference between the peak valve step position and the average valve step position by a predetermined percentage threshold value.

23. The method of claim 18 wherein the changing in e) comprises:

g) determining an inhale time associated with the inhalation state;

h) determining an exhale time associated with the unload portion of the exhalation state and based at least in part on the determined inhale time;

i) beginning the exhale time after the transition from the inhalation state to the exhalation state;

j) decrementing the valve step position according to an unloading function until a second predetermined breathing gas pressure value is achieved; and

k) changing the valve step position in response to a difference between the sensed breathing gas pressure and the second predetermined breathing gas pressure value after the second predetermined breathing gas pressure value is achieved and until the exhale time expires.

24. The method of claim 23 wherein the determining in g) comprises:

l) starting an inhalation timer after the start of the inhalation state is detected;

m) determining a peak valve step position for the inhalation state; and

n) stopping the inhalation timer after the peak valve step position for the inhalation state is determined.

25. The method of claim 23 wherein the exhale time in h) is a product of a predetermined exhale time factor and the determined inhale time.

26. The method of claim 18 wherein the changing in f) comprises:

g) incrementing the valve step position according to a loading function until the first predetermined breathing gas pressure value is achieved; and

h) changing the valve step position in response to a difference between the sensed breathing gas pressure and the first predetermined breathing gas pressure value after the first predetermined breathing gas pressure value is achieved.

27. A method of providing a breathing gas comprising:

a) sensing a breathing gas pressure associated with delivery of the breathing gas;

b) determining a breath cycle time associated with at least a portion of a current inhalation state of a current breathing cycle and a portion of a previous breathing cycle;

c) changing a valve step position associated with a variable position valve in response to a difference between the sensed breathing gas pressure and a first predetermined breathing gas pressure value during the current inhalation state;

d) determining a transition from the current inhalation state to a current exhalation state of the current breathing cycle based at least in part on the changing valve step position;

e) changing the valve step position to cause a first change in the breathing gas pressure during an unload portion of the current exhalation state based at least in part on the determined transition; and

f) changing the valve step position to cause a second change in the breathing gas pressure during a load portion of the current exhalation state based at least in part on the first predetermined breathing gas pressure value.

28. The method of claim 27 wherein the determining in b) comprises:

g) determining a peak valve step position for a previous inhalation state of the previous breathing cycle;

h) starting a breath cycle timer after the peak valve step position for the previous breathing cycle is determined;

i) determining a peak valve step position for the current inhalation state; and

j) stopping the breath cycle timer after the peak valve step position for the current inhalation state is determined.

29. The method of claim 27 wherein the determining in d) comprises:

g) calculating a first transition variable based at least in part on an instantaneous valve step position;

h) calculating a second transition variable based at least in part on a peak valve step position; and

i) identifying the transition from the current inhalation state to the current exhalation state after the first transition variable is less than or equal to the second transition variable.

30. The method of claim 29 wherein the calculating in g) comprises:

j) determining an average valve step position;

k) identifying the instantaneous valve step position; and

l) calculating the first transition variable by subtracting the average valve step position from the instantaneous valve step position.

31. The method of claim 29 wherein the calculating in h) comprises:

j) determining an average valve step position;

k) determining a peak valve step position for the current inhalation state; and

l) calculating the second transition variable by multiplying a difference between the peak valve step position and the average valve step position by a predetermined percentage threshold value.

32. The method of claim 27 wherein the changing in e) comprises:

g) determining an unloading time associated with the unload portion of the current exhalation state and based at least in part on the determined breath cycle time;

h) beginning the unloading time after the transition from the current inhalation state to the current exhalation state;

i) decrementing the valve step position according to an unloading function until a second predetermined breathing gas pressure value is achieved; and

j) changing the valve step position in response to a difference between the sensed breathing gas pressure and the second predetermined breathing gas pressure value after the second predetermined breathing gas pressure value is achieved and until the unloading time expires.

33. The method of claim 32 wherein the unloading time in g) is a product of a predetermined unload time factor and the determined breath cycle time.

34. The method of claim 27 wherein the changing in f) comprises:

g) determining a loading time associated with the load portion of the current exhalation state and based at least in part on the determined breath cycle time;

h) beginning the loading time after the unload portion of the current exhalation state;

i) incrementing the valve step position according to a loading function until the first predetermined breathing gas pressure value is achieved; and

j) changing the valve step position in response to a difference between the sensed breathing gas pressure and the first predetermined breathing gas pressure value after the first predetermined breathing gas pressure value is achieved and until the loading time expires.

35. The method of claim 34 wherein the loading time in g) is a product of a predetermined load time factor and the determined breath cycle time.

36. A method of providing a breathing gas comprising:

a) sensing a sensed parameter associated with delivery of the breathing gas;

b) changing a control parameter associated with a flow/pressure control element in response to a difference between the sensed parameter and a first predetermined sensed parameter value during a first portion of a current breathing cycle;

c) determining a transition from the first portion to a second portion of the current breathing cycle based at least in part on the changing control parameter;

d) changing the control parameter to cause a first change in the sensed parameter during the second portion of the current breathing cycle based at least in part on the determined transition; and

e) changing the control parameter to cause a second change in the sensed parameter during a third portion of the current breathing cycle based at least in part on the first predetermined sensed parameter value.

37. The method of claim 36 wherein the sensed parameter is breathing gas pressure, breathing gas flow, breathing gas temperature, or breathing gas composition.

38. The method of claim 36 wherein the flow/pressure control element includes a variable position valve and the control parameter includes a valve step position.

39. The method of claim 36 wherein the flow/pressure control element includes a variable speed blower and the control parameter includes a blower speed.

40. The method of claim 36 wherein the changing in b) comprises:

f) determining a valve step error based at least in part on the sensed parameter and the first predetermined sensed parameter value; and

g) changing the control parameter to minimize the valve step error.

41. The method of claim 40 wherein the sensed parameter is a breathing gas pressure and the determining in f) comprises:

f) determining a current pressure error by comparing the first predetermined sensed parameter value to the sensed parameter;

g) determining a pressure error difference between the current pressure error and a previous pressure error;

h) determining a pressure error sum by adding the current pressure error and the previous pressure error; and

i) calculating the valve step error by adding a first product of the current pressure error and a first constant, a second product of the pressure error difference and a second constant, and a third product of the pressure error sum and a third constant.

42. The method of claim 36 wherein the flow/pressure control element is a variable position valve, the control parameter is a valve step position, and the determining in c) comprises:

f) determining the unload threshold value; and

g) determining whether the changing valve step position is less than the unload threshold value.

43. The method of claim 42 wherein the determining in f) comprises:

h) determining a breath rate;

i) determining a median valve step position;

j) determining a peak valve step position for one or more previous breath cycles;

k) identifying a predetermined percentage unloading factor associated with the determined breath rate; and

l) calculating the unload threshold value based at least in part on the determined median valve step position.

44. The method of claim 43 wherein the determining in h) comprises:

m) recording a start time for a current breath during a previous breathing cycle;

n) recording an end time for the current breath during a current breathing cycle; and

o) calculating the breath rate based on the start and end times for the current breath.

45. The method of claim 44 wherein the recording in m) comprises:

p) determining an upper breath rate threshold value;

q) determining a lower breath rate threshold value;

r) identifying when a previous slope of a previous valve step position change is negative during the previous breathing cycle;

s) monitoring the valve step position as it becomes less than the upper breath rate threshold value during the previous breathing cycle; and

t) recording the start time for the current breath after the valve step position becomes less than the lower breath rate threshold value.

46. The method of claim 45 wherein the determining in p) comprises:

u) calculating the upper breath rate threshold value by adding a predetermined percentage of the median valve step position to the median valve step position.

47. The method of claim 45 wherein the determining in q) comprises:

u) calculating the lower breath rate threshold value by subtracting a predetermined percentage of the median valve step position from the median valve step position.

48. The method of claim 44 wherein the recording in n) comprises:

p) determining an upper breath rate threshold value;

q) determining a lower breath rate threshold value;

r) identifying when a current slope of a current valve step position change is negative during the current breathing cycle;

s) monitoring the valve step position as it becomes less than the upper breath rate threshold value during the current breathing cycle; and

t) recording an end time for the current breath after the valve step position becomes less than the lower breath rate threshold value during the current breathing cycle.

49. The method of claim 43 wherein the determining in i) comprises:

m) identifying a present valve step position; and

n) calculating the median valve step position by adding a first predetermined percentage of the present valve step position to a second predetermined percentage of a previous median valve step position, wherein a sum of the first and second predetermined percentages is one.

50. The method of claim 43 wherein the determining in j) comprises:

m) determining an inhalation threshold;

n) after the changing valve step position exceeds the inhalation threshold, identifying a highest valve step position between a present valve step position and one or more previous valve step positions; and

o) if the highest valve step position does not change for a predetermined peak valve step time, identifying the highest valve step position as the peak valve step position.

51. The method of claim 50 wherein the determining in m) comprises:

p) determining a difference between the peak valve step position and the median valve step position;

q) determining a product of the determined difference and a predetermined inhalation scaling factor; and

r) adding the determined product to the median valve step position.

52. The method of claim 43 wherein the calculating in l) comprises:

m) determining a difference between the peak valve step position and the median valve step position;

n) determining a product of the determined difference and the predetermined percentage unloading factor; and

o) adding the determined product to the median valve step position.

53. The method of claim 36 wherein the changing in d) comprises:

f) determining a second predetermined sensed parameter value;

g) setting a decrease timer to a predetermined unload time;

h) determining a sequence of predetermined sensed parameter values for the second portion of the current breathing cycle based at least in part on the first and second predetermined sensed parameter values; and

i) changing the control parameter based at least in part on the sequence of predetermined sensed parameter values until the decrease timer is expired.

54. The method of claim 51 wherein the flow/pressure control element is a variable position valve, the control parameter is a valve step position, the first predetermined sensed parameter value is a prescribed pressure, the second predetermined sensed parameter value is an unload pressure, and the determining in f) comprises:

j) determining a peak valve step position;

k) determining a median valve step position;

l) calculating a pressure offset by subtracting the median valve step position from the peak valve step position to obtain a first intermediate result, multiplying the first intermediate result by a first constant to obtain a second intermediate result, and multiplying the second intermediate result by the prescribed pressure; and

m) calculating the unload pressure by subtracting the pressure offset from the prescribed pressure.

55. The method of claim 36 wherein the changing in e) comprises:

f) determining a second predetermined sensed parameter value;

g) setting an increase timer to a predetermined load time;

h) determining a sequence of predetermined sensed parameter values for the third portion of the current breathing cycle based at least in part on the first and second predetermined sensed parameter values; and

i) changing the control parameter based at least in part on the sequence of predetermined sensed parameter values until the increase timer is expired.

56. A method of providing a breathing gas comprising:

a) sensing a breathing gas pressure associated with delivery of the breathing gas;

b) changing a valve step position associated with a variable position valve in response to a difference between the sensed breathing gas pressure and a first predetermined breathing gas pressure value during a first portion of a current breathing cycle;

c) determining a transition from the first portion to a second portion of the current breathing cycle based at least in part on the changing valve step position;

d) changing the valve step position to cause a first change in the breathing gas pressure during the second portion of the current breathing cycle based at least in part on the determined transition; and

e) changing the valve step position to cause a second change in the breathing gas pressure during a third portion of the current breathing cycle based at least in part on the first predetermined breathing gas pressure value.

57. The method of claim 56 wherein the changing in b) comprises:

f) determining a valve step error based at least in part on the sensed parameter and the first predetermined sensed parameter value; and

g) changing the control parameter to minimize the valve step error.

58. The method of claim 56 wherein determining in c) comprises:

f) determining the unload threshold value; and

g) determining whether the changing valve step position is less than the unload threshold value.

59. The method of claim 56 wherein the changing in d) comprises:

f) determining a second predetermined breathing gas pressure value;

g) setting a decrease timer to a predetermined unload time;

h) determining a sequence of predetermined breathing gas pressure values for the second portion of the current breathing cycle based at least in part on the first and second predetermined breathing gas pressure values; and

i) changing the valve step position based at least in part on the sequence of predetermined breathing gas pressure values until the decrease timer is expired.

60. The method of claim 56 wherein the changing in e) comprises:

f) determining a second predetermined breathing gas pressure value;

g) setting an increase timer to a predetermined load time;

h) determining a sequence of predetermined breathing gas pressure values for the third portion of the current breathing cycle based at least in part on the first and second predetermined breathing gas pressure values;

i) changing the valve step position based at least in part on the sequence of predetermined breathing gas pressure values until the increase timer is expired.

61. A method of providing a breathing gas to a patient comprising:

controlling a valve position to output a first target gas pressure level to the patient during at least a portion of the patient'"'"'s inhalation breathing state;

monitoring an actual gas pressure level output to the patient;

determining a valve position setting based on the monitored gas pressure level;

determining a valve position setting threshold;

determining at least a second target gas pressure level that is less than the first target gas pressure level;

if the valve position setting falls below the valve position setting threshold, controlling the valve position to output the second target gas pressure level to the patient for a predetermined time period during at least a first portion of the patient'"'"'s exhalation breathing state; and

controlling the valve position to output the first target gas pressure level to the patient after the predetermined time period has expired during at least a second portion of the patient'"'"'s exhalation breathing state.

62. The method of claim 61 wherein determining a valve position threshold comprises determining a difference between at least a peak valve position and a median valve position and determining a patient breathing rate.

63. The method of claim 61 wherein determining at least a second target gas pressure level that is less than the first target gas pressure level comprises lowering the at least first target pressure by a quantity based at least in part on valve position.

64. The method of claim 61 wherein controlling the valve position to output the second target gas pressure level to the patient for a predetermined time period during at least a first portion of the patient'"'"'s exhalation breathing state comprising outputting at least the second target gas pressure level at the onset of exhalation for a predetermined time period.

65. The method of claim 61 wherein controlling the valve position to output the second target gas pressure level to the patient for a predetermined time period during at least a first portion of the patient'"'"'s exhalation breathing state comprises determining a plurality of decrease target gas pressure levels between the first target gas pressure level and the second target gas pressure level.

66. The method of claim 61 wherein controlling the valve position to output the first target gas pressure level to the patient after the predetermined time period has expired comprises determining a plurality of increase target gas pressure levels between the second target gas pressure level and the first target gas pressure level.

67. The method of claim 61 wherein determining a valve position setting based on the monitored gas pressure level comprises comparing the first target gas pressure level to the monitored gas pressure level.