Percutaneous heart valve

• US 7,621,948 B2
• Filed: 07/20/2004
• Issued: 11/24/2009
• Est. Priority Date: 07/21/2003
• Status: Active Grant

• Current Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Original Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Inventors: Herrmann, Howard C, Ananthasuresh, Suresh G. K., Mankame, Nilesh
• Primary Examiner(s): GHERBI, SUZETTE JAIME J
• Application Number:
  US10/565,142
• Publication Number:
  US 20070016286A1
• Time in Patent Office: 1,953 Days
• Field of Search: 623 21- 238
• US Class Current: 623/2.1
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/243 Deployment by mechanical expansion
• CPC Class Codes: Y10S 623/904 Heart

Abstract

A percutaneously inserted bistable heart valve prosthesis is folded inside a catheter for transseptal delivery to the patient'"'"'s heart for implantation. The heart valve has an annular ring, a body member having a plurality of legs, each leg connecting at one end to the annular ring, claws that are adjustable from a first position to a second position by application of external force so as to allow ingress of surrounding heart tissue into the claws in the second position, and leaflet membranes connected to the annular ring, the body member and/or the legs, the leaflet membranes having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough. The heart valve is designed such that upon removal of the external force the claws elastically revert to the first position so as to grip the heart tissue positioned within the claws, thereby holding the heart valve in place. The body member and claws may be integrated into a one-piece design. The heart valve may be used as a prosthesis for the mitral valve, aortic valve, pulmonary valve, or tricuspid valve by adapting the annular ring to fit in a respective mitral, aortic, pulmonary, or tricuspid valve opening of the heart.

Claims

1. A bistable percutaneous heart valve, comprising:

an elastic annular ring;

a body member having a plurality of legs, each leg connecting at one end to said annular ring;

at least two claws that are adjustable from a first position to a second position by application of external force so as to allow ingress of surrounding heart tissue into said claws in said second position, wherein upon removal of the external force the claws elastically revert to the first position so as to grip the heart tissue positioned within the claws, thereby holding said heart valve in place; and

at least one leaflet membrane connected to at least one of said annular ring, said body member and said legs, said at least one leaflet membrane having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough.

2. A heart valve as in claim 1, wherein said annular ring is adapted to fit in a mitral valve opening of a heart.

3. A heart valve as in claim 1, wherein said annular ring is adapted to fit in an aortic valve opening of a heart.

4. A heart valve as in claim 1, wherein said annular ring is adapted to fit in a pulmonary valve opening of a heart.

5. A heart valve as in claim 1, wherein said annular ring is adapted to fit in a tricuspid valve opening of a heart.

6. A heart valve as in claim 1, wherein said annular ring, said body member, said legs, said claws and said at least one leaflet membrane fold into a collapsed position for insertion into a catheter for percutaneous delivery to the heart for implantation.

7. A heart valve as in claim 6, wherein said heart valve has a first stable position after passage through the catheter and a second stable position to which the heart valve is forced for implantation.

8. A heart valve as in claim 7, wherein said body member and legs push outward on said annular ring in said second stable position so as to assist anchoring said heart valve in said heart tissue.

9. A heart valve as in claim 1, wherein said annular ring is expandable radially to anchor the heart valve at an implantation position.

10. A heart valve as in claim 7, wherein each claw is connected to at least one of said annular ring and a leg so as to permit movement of each claw from said first position to said second position.

11. A heart valve as in claim 1, wherein further comprising at least one filament connecting said body member to said claws, said filament extending proximally from said heart valve so as to permit control of said claws between said first and second positions from a location remote from an implantation position of said heart valve.

12. A heart valve as in claim 11, further comprising a motion restraint that restrains one side of said claws while said at least one filament is connected to another side of said claws, whereby pulling said at least one filament causes the claws to open.

13. A heart valve as in claim 1, wherein said body member and claws are integrated into a one-piece design.

14. A bistable percutaneous heart valve, comprising:

an expandable elastic annular ring;

a body member having a plurality of legs, each leg connecting at one end to said annular ring;

at least two claws that are adjustable to guide said heart valve to an implantation position; and

at least one leaflet membrane connected to at least one of said annular ring, said body member and said legs, said at least one leaflet membrane having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough,

wherein said expandable annular ring expands to anchor said heart valve at said implantation position.

15. A heart valve as in claim 14, wherein said annular ring, said body member, said legs, said claws and said at least one leaflet membrane fold into a collapsed position for insertion into a catheter for percutaneous delivery to the implantation position.