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Coated stent

  • US 7,622,135 B2
  • Filed: 05/27/2003
  • Issued: 11/24/2009
  • Est. Priority Date: 10/22/2001
  • Status: Expired due to Fees
First Claim
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1. A coated stent comprising:

  • a coating composition comprising an HMG-CoA reductase inhibitor in an effective amount, of about 1 to 50 wt.-%, and a polymeric carrier component;

    wherein the polymeric carrier component comprises a polymer selected from polycaprolactone, ethylene-vinyl acetate polymer, and a two-part silicone rubber,wherein the HMG-CoA reductase inhibitor is selected from the group consisting of cerivastatin, fluvastatin, simvastatin, lovastatin, atorvastatin, pravastatin and mixtures thereof, andwherein the HMG-CoA reductase inhibitor is released from the coated stent at a rate of >

    20 μ

    g/ml per day.

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