Implantable medical devices using heuristic filtering in cardiac event detection

• US 7,623,913 B2
• Filed: 08/01/2006
• Issued: 11/24/2009
• Est. Priority Date: 08/01/2006
• Status: Active Grant

• Current Assignee: Cameron Health Inc (Boston Scientific Corporation)
• Original Assignee: Cameron Health Inc (Boston Scientific Corporation)
• Inventors: Phillips, James William
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Behringer; Luther G
• Application Number:
  US11/497,204
• Publication Number:
  US 20080045850A1
• Time in Patent Office: 1,211 Days
• Field of Search: 367/45, 708322-323, 375/130, 375/145, 375/149, 375/232, 375/295, 375/376, 600508-528, 607/9, 128/901, 128/902, 702/60, 341/61
• US Class Current: 600/517
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/346 Analysis of electrocardiograms
• CPC Class Codes: A61N 1/37 Monitoring; Protecting

Abstract

Methods for performing cardiac signal analysis in an implanted medical device, and devices configured to perform illustrative methods of cardiac signal analysis. A cardiac signal is captured by an implanted device using implanted electrodes and, during at least certain conditions, the cardiac signal undergoes heuristic filtering. In some embodiments, heuristic filtering is achieved by modifying a signal or value that is used as an indicator of received signal amplitude. In an illustrative example, the heuristic filtering includes periodically incrementing or decrementing the signal or value toward a desired quiescent point, where the heuristic filter period is significantly longer than the sampling period for the signal itself. In another illustrative example, the heuristic filter frequency can be adjusted dynamically to keep the signal average near the desired quiescent point.

Claims

1. A method of cardiac signal analysis comprising:

capturing a cardiac signal using implanted electrodes;

conditioning and amplifying the signal;

performing analog-to-digital conversion on the signal; and

applying a heuristic filter to the captured cardiac signal by repeatedly performing the following at a predetermined interval;

a) calculating an actual quiescent point of the analog-to-digital converted signal; and

b) adjusting the analog-to-digital conversion of the signal to modify the actual quiescent point toward a desired quiescent point; and

adjusting the predetermined interval by calculating a quiescent distance between the actual quiescent point and the desired quiescent point; and

;

x) reducing the predetermined interval if the quiescent distance is greater than a first threshold;

y) increasing the predetermined interval if the quiescent distance is less than a second threshold;

or

z) if the quiescent distance is between the first and second thresholds, making no adjustment to the predetermined interval.

2. The method of claim 1, wherein:

the step of performing analog-to-digital conversion includes converting the captured cardiac signal to a series of digital values stored on an accumulator; and

the step of adjusting the analog-to-digital conversion is performed by modifying a value stored on the accumulator at periodic intervals.

3. The method of claim 2, wherein the step of calculating an actual quiescent point is performed by averaging several values stored on the accumulator.

4. The method of claim 1, wherein:

the step of adjusting the analog-to-digital conversion is performed by generating a heuristic offset and adding the heuristic offset to the digitally converted cardiac signal to generate an adjusted digital representation of the captured cardiac signal; and

the actual quiescent point is calculated by observing a value of at least one sample of the adjusted digital representation.

5. The method of claim 1 wherein the analog-to-digital conversion of the signal includes sampling the signal using a sampling interval, and further wherein the sampling interval is not the same as the predefined interval.

6. The method of claim 5 wherein the step of adjusting the predefined interval selects from a range of interval values that includes values that are greater than the sampling interval and values that are less than the sampling interval.

7. A method of cardiac signal analysis comprising:

capturing a cardiac signal between implanted electrodes;

conditioning the cardiac signal for use in analysis, including sampling the cardiac signal;

creating an adjusted signal, the adjusted signal representing a series of samples of the conditioned cardiac signal added to an offset;

repeatedly performing at predefined intervals;

a) calculating an average of the adjusted signal over a predetermined period of time; and

b) modifying the offset depending upon whether the average of the adjusted signal is greater than or less than a predetermined value; and

using the calculated average of the adjusted signal to adjust the predefined intervals by;

increasing the duration of the predefined intervals if the calculated average is close to a desired quiescent point;

or

decreasing the duration of the predefined intervals if the calculated average is greater than a desired quiescent point.

8. A method of treating a patient using an implanted cardiac stimulus device system, the method comprising:

utilizing a first method of cardiac signal analysis during a first time period;

delivering cardiac stimulus; and

during a second time period following delivery of the cardiac stimulus, performing the method of claim 7.

9. The method of claim 8, further comprising:

during the second time period, comparing the adjusted signal to a predetermined threshold to detect a threshold crossing;

ending the second time period when a threshold crossing is detected.

10. An implantable cardiac rhythm management device comprising:

at least a pair of sensing electrodes;

an analog-to-digital converter (ADC) configured to convert a signal received from the sensing electrodes into a digital representation; and

control circuitry coupled to the ADC that is configured to;

a) perform the following steps repeatedly at a predefined interval;

calculate an actual quiescent point of the ADC output;

calculate a quiescent distance from the actual quiescent point to a desired quiescent point; and

increment or decrement a counter in the ADC to reduce the quiescent distance; and

b) at a fixed interval, compare the quiescent distance to a first threshold and a second threshold and

if the quiescent distance is shorter than the first threshold, increase the duration of the predetermined interval;

if the quiescent distance is longer than the second threshold, decrease the duration of the predetermined interval;

else

leave the predetermined interval unchanged.

11. The device of claim 10 wherein the analog-to-digital converter is configured to use a sampling interval that is not the same as the predefined interval.

12. The device of claim 11 wherein the control circuitry is configured such that the step of adjusting the predefined interval selects from a range of interval values that includes values that are greater than the sampling interval and values that are less than the sampling interval.