Dermatological composition

• US 7,625,575 B2
• Filed: 09/19/2007
• Issued: 12/01/2009
• Est. Priority Date: 11/26/2003
• Status: Expired due to Fees

• Current Assignee: EI, LLC (Steris PLC)
• Original Assignee: Harmony Labs Incorporated
• Inventors: Wagoner, Bruce Kevin
• Primary Examiner(s): LEITH, PATRICIA A
• Application Number:
  US11/857,958
• Publication Number:
  US 20080138451A1
• Time in Patent Office: 804 Days
• Field of Search: None
• US Class Current: 424/401
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 36/28 Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• CPC Class Codes: A61K 36/48 Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
• CPC Class Codes: A61K 8/922 of vegetable origin
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61Q 15/00 Anti-perspirants or body deodorants deodorisation of air A61L9/00
• CPC Class Codes: A61Q 3/00 Manicure or pedicure preparations

Abstract

Dermatological compositions containing a humectant, e.g., at least one of urea, ammonium lactate, and glycerin, and an emollient, e.g., at least one of Shea or cocoa butter, glycine soja sterol and hybrid sunflower oil. The compositions of the invention may be utilized for treatment or amelioration of skin disorders or adverse physiological conditions, and such compositions may be employed as a base for cosmetic or pharmaceutical formulations for dermal administration.

Claims

1. A dermatological composition, consisting of water and the following components in the following respective concentration ranges:

2. A dermatological composition according to claim 1, wherein the concentration of urea is in a range of from 21 to 40 weight %.

3. A dermatological composition according to claim 1, wherein the composition consists of water and the following components in the following respective concentrations:

4. The composition of claim 3, in the form of a suspension.

5. A dermatological composition according to claim 1, wherein the composition consists of water and the following components in the following respective concentrations:

6. The composition of claim 5, in the form of an emulsion.

9. A method for treating a skin condition selected from the group consisting of psoriasis, xerosis, ichthyosis, keratosis, keratoderma, dermatitis, pruritus, eczema and calluses comprising topically applying an effective amount of the composition of claim 1 to a subject having said skin condition.

10. A method for softening skin tissue or softening nails comprising topically applying an effective amount of the composition of claim 1 to skin or nails of a subject in need thereof.

11. A lotion, cream, ointment, emulsion, suspension or gel consisting essentially of the dermatological composition of any one of claims 1, 3, 5, or 7.

7. A dermatological composition consisting of water and the following components in the following respective concentration ranges:

8. The dermatological composition of claim 7, wherein the concentration of urea is 40%.