Reagent and sample handling device for automatic testing system

• US 7,628,954 B2
• Filed: 05/04/2005
• Issued: 12/08/2009
• Est. Priority Date: 05/04/2005
• Status: Expired due to Fees

• Current Assignee: Abbott Laboratories Incorporated
• Original Assignee: Abbott Laboratories Incorporated
• Inventors: Luoma, Robert Paul II, Arnquist, David Charles, Johnson, Ryan Patrick, Gomm, Cordell Kay
• Primary Examiner(s): Gakh; Yelena G
• Assistant Examiner(s): WEISZ, DAVID G
• Application Number:
  US11/122,280
• Publication Number:
  US 20060263248A1
• Time in Patent Office: 1,679 Days
• Field of Search: 422 63- 67
• US Class Current: 422/63
• CPC Class Codes: G01N 2035/00049 for loading/unloading a carousel
• CPC Class Codes: G01N 2035/00316 Detecting door closure
• CPC Class Codes: G01N 2035/00752 bar codes
• CPC Class Codes: G01N 2035/00891 Displaying information to the operator
• CPC Class Codes: G01N 2035/0443 for reagents
• CPC Class Codes: G01N 2035/0491 Position sensing, encoding; closed-loop control
• CPC Class Codes: G01N 35/00712 Automatic status testing, e.g. at start-up or periodic
• CPC Class Codes: G01N 35/00722 Communications; Identification
• CPC Class Codes: G01N 35/0099 comprising robots or similar manipulators robots per se B25J
• CPC Class Codes: G01N 35/025 having a carousel or turntable for reaction cells or cuvettes
• CPC Class Codes: G01N 35/04 Details of the conveyor system G01N35/021 - G01N35/028 take precedence
• CPC Class Codes: Y10S 901/01 Mobile robot
• CPC Class Codes: Y10T 436/11 Automated chemical analysis

Abstract

A handling device for samples and reagents to be used in testing in a system. Carriers of samples and reagents are loaded on a platform which detects the presence of, and proper loading of, such carriers. The carriers are moved from the platform by a transporter to a bar code reader for identification. A reagent container is rotated during reading to facilitate identification. The transporter further moves identified reagent carriers to a carousel on which the carriers automatically secured for storage awaiting use in testing. The carousel rotates, and selected reagent containers rotate on the rotating carousel, during storage.

Claims

1. In a testing system, a handling device for samples and reagents to be used in testing in said system, said samples being transportable by a sample carrier and said reagents being transportable by a reagent carrier, comprising:

a platform defining a plurality of locations on which said carriers can be placed from a loading side for loading into said testing system;

a position indicator at each location, each position indicator for providing feedback to the system as to the presence or not of a particular carrier at each location, each position indicator having four indicating positions, each position indicator cooperating with said platform, each position indicator biased upwardly, whereby when no carrier is in a location on said platform,

said position indicator at said location is in its uppermost position,

when either a sample carrier or a reagent carrier is only partially loaded at said location, said position indicator is in a position lower than said uppermost position,

when a sample carrier is properly loaded at said location, said position indicator is in a position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, and

when a reagent carrier is properly loaded at said location, said position indicator is in a position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, provided that said position of said position indicator when said reagent carrier is properly loaded at said location is different from said position of said position indicator when said sample carrier is properly loaded at said location; and

a sensor for detecting the position of said position indicator.

2. The handling device for samples and reagents of claim 1, wherein said sensor comprises first and second proximity sensors and said position indicator includes first and second ears aligned with said first and second proximity sensors respectively, wherein

when no carrier is in a location on said platform,

and said position indicator at said location is in its uppermost position,

said ears are spaced from said proximity sensors,

when either a sample carrier or a reagent carrier is only partially loaded at said location, said position indicator is in a position lower than said uppermost position, said first ear is proximate said first proximity sensor and said second ear is spaced from said second proximity sensor,

when a sample carrier is properly loaded at said location, said position indicator is in a position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, said first ear is proximate said first proximity sensor and said second ear is proximate said second proximity sensor, and

when a reagent carrier is properly loaded at said location, said position indicator is in a position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, said first ear is spaced from said first proximity sensor and said second ear is proximate said second proximity sensor.

4. The handling device for samples and reagents of claim 2, wherein said proximity sensors are electric eyes, and said ears are detected as proximate thereto when said electric eyes are blocked.

3. In a testing system, a handling device for samples and reagents to be used in testing in said system, said samples being transportable by a sample carrier and said reagents being transportable by a reagent carrier, comprising:

a platform defining a plurality of locations on which said carriers can be placed from a loading side for loading into said testing system;

a position indicator at each location, each position indicator for providing feedback to the system as to the presence or not of a particular carrier at each location, each position indicator having four indicating positions, each position indicator cooperating with said platform, each position indicator biased upwardly, whereby when no carrier is in a location on said platform,

said position indicator at said location is in its uppermost position,

when either a sample carrier or a reagent carrier is only partially loaded at said location, said position indicator is in a position lower than said uppermost position,

when a sample carrier is properly loaded at said location, said position indicator is in a position, lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location and

when a reagent carrier is properly loaded at said location, said position indicator is in a position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, provided that said position of said position indicator when said reagent carrier is properly loaded at said location is different from said position of said position indicator when said sample carrier is properly loaded at said location; and

a sensor for detecting the position of said position indicator, wherein said sensor comprises first and second proximity sensors and said position indicator includes first and second ears aligned with said first and second proximity sensors respectively, wherein

when no carrier is in a location on said platform,

and said position indicator at said location is in its uppermost position,

said ears are spaced from said proximity sensors,

when either a sample carrier or a reagent carrier is only partially loaded at said location, said position indicator is in a position lower than said uppermost position, said first ear is proximate said first proximity sensor and said second ear is spaced from said second proximity sensor,

when a sample carrier is properly loaded at said location, said position indicator is in a position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, said first ear is proximate said first proximity sensor and said second ear is proximate said second proximity sensor, and

when a reagent carrier is properly loaded at said location, said position indicator is in a position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, said first ear is spaced from said first proximity sensor and said second ear is proximate said second proximity sensor,

wherein said position indicator is pivotally secured beneath said platform on one end and said ears are disposed on the other end of said position indicator.

5. In a testing system, a handling device for samples and reagents to be used in testing in said system, said samples being transportable by a sample carrier and said reagents being transportable by a reagent carrier, comprising:

a platform defining a plurality of locations on which said carriers can be placed from a loading side for loading into said testing system;

a position indicator at each location, each position indicator for providing feedback to the system as to the presence or not of a particular carrier at each location, each position indicator having four indicating positions, each position indicator cooperating with said platform, each position indicator biased upwardly, whereby when no carrier is in a location on said platform,

said position indicator at said location is in its uppermost position,

when either a sample carrier or a reagent carrier is only partially loaded at said location, said position indicator is in a position lower than said uppermost position,

when a sample carrier is properly loaded at said location, said position indicator is in a position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, and

when a reagent carrier is properly loaded at said location, said position indicator is in a lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, provided that said position of said position indicator when said reagent carrier is properly loaded at said location is different from said position of said position indicator when said sample carrier is properly loaded at said location; and

a sensor for detecting the position of said position indicator,

wherein said platform includes openings therethrough at each platform location, and said position indicator includes projections extending through said openings and adapted to be selectively engaged by a sample carrier or a reagent carrier when said sample carrier or said reagent carrier is in either a partially loaded position or in a properly loaded position.

6. The handling device for samples and reagents of claim 5, wherein:

said platform at each location includes a flat portion and a raised end at said loading side;

said projections include first and second knuckles, wherein

said first knuckle projects above said platform raised end a first distance when said position indicator is in its uppermost position, and

said second knuckle projects above said platform flat portion a second distance when said position indicator is in its uppermost position;

whereby

a partially loaded carrier rests on said raised end and engages said first knuckle to force said position indicator down said first distance to a position lower than said uppermost position, and

one of said sample and reagent carriers when properly loaded on said platform engages said second knuckle to force said position indicator down said second distance to one of said positions lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location.

7. The handling device for samples and reagents of claim 6,

wherein said platform locations include raised ledges along opposite sides of said platform flat portion, said raised ledges being adapted to support the other of said sample carrier and reagent carrier above said flat portion when properly loaded;

and

further comprising a third knuckle projecting above said ledges a third distance when said position indicator is in said uppermost position;

whereby the other of said sample carrier and said reagent carrier when properly loaded on said platform engages said third knuckle to force said position indicator down said third distance to the other of said positions lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location.

8. The handling device for samples and reagents of claim 7, wherein said third distance is greater than said second distance and said second distance is greater than said first distance.

9. The handling device for samples and reagents of claim 7, wherein said sensor comprises first and second proximity sensors and said position indicator

is spaced from said proximity sensors in said uppermost position,

is proximate said first proximity sensor and is spaced from said second proximity sensor in said position lower than said uppermost position,

is proximate both said first and second proximity sensors in said position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location, and

is spaced from said first proximity sensor and proximate said second proximity sensor in said position lower than said uppermost position and lower than the position of the position indicator when either a sample carrier or a reagent carrier is only partially loaded at said location.

10. The handling device for samples and reagents of claim 9, wherein:

said position indicator includes first and second ears aligned with said first and second proximity sensors respectively;

said proximity sensors are electric eyes; and

said ears are detected as proximate thereto when said electric eyes are blocked.