Exercise responsive pacemaker tuning method using Doppler blood flow measurements to adjust pacing for optimized flow

• US 7,630,766 B2
• Filed: 06/26/2003
• Issued: 12/08/2009
• Est. Priority Date: 07/03/2002
• Status: Expired due to Fees

• Current Assignee: Uscom Ltd.
• Original Assignee: Uscom Ltd.
• Inventors: Phillips, Robert Allan
• Primary Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US10/519,863
• Publication Number:
  US 20050245981A1
• Time in Patent Office: 2,357 Days
• Field of Search: 607/27, 607/19
• US Class Current: 607/19
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61N 1/37 Monitoring; Protecting
• CPC Class Codes: A61N 1/37217 characterised by the communication link, e.g. acoustic or tactile

Abstract

A method of tuning a cardiac prosthetic pacing device includes (a) monitoring the flow output from the heart, and (b) adjusting the timing of pacing events by the cardiac prosthetic pacing device so as to optimise the flow from the heart under operational conditions.

Claims

1. A method of tuning a cardiac prosthetic pacing device, the method comprising the steps of:

(a) monitoring the flow output from the heart utilizing a transcutaneous continuous wave Doppler signal directed at the heart to obtain a signal indicative of intra-cardiac blood flow velocity under a number of different operation conditions for a patient including walking and running;

(b) constructing a table of correspondence between activity type and flow rate and storing said table on said cardiac prosthetic pacing device; and

(c) using said table, adjusting the timing of pacing events by said cardiac prosthetic pacing device so as to optimise the flow from the heart under operational conditions.

2. A method as claimed in claim 1 wherein said monitoring is repeated under a number of different pharmalogical conditions for a patient.

3. A method as claimed in claim 1 wherein said monitoring is conducted on a number of patients.

4. A method as claimed in claim 3 wherein results from the number of patients are statistically combined.

5. A method as claimed in claim 4 wherein the statistical combination of results includes averaging for at least one of age, sex and weight.

6. A method as claimed in claim 1 wherein the adjustment of the timing of pacing events includes calculating a difference between a current rate and an activity rate obtained from said table and adjusting the timing of pacing events so that the current rate is closer to the activity rate.

7. A method as claimed in claim 6 wherein said adjustment operates in a feedback loop constantly with a predetermined delay.