Syringe devices and methods for mixing and administering medication

• US 7,635,344 B2
• Filed: 05/21/2007
• Issued: 12/22/2009
• Est. Priority Date: 10/13/2004
• Status: Active Grant

• Current Assignee: Hyprotek, Inc.
• Original Assignee: Hyprotek, Inc.
• Inventors: Tennican, Patrick O., Phipps, L. Myles, Michaelsen, Russell A.
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): Anderson; Michael J
• Application Number:
  US11/751,422
• Publication Number:
  US 20070265574A1
• Time in Patent Office: 946 Days
• Field of Search: 604/88, 604/187, 604/190, 604/82, 604/87, 604 89- 91, 604191-208, 604/211
• US Class Current: 604/88
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2062 with directional valves
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2086 for fluid filtration
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2005/3117 Means preventing contamination of the medicament compartment of a syringe
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 5/002 Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001
• CPC Class Codes: A61M 5/204 connected to external reservoirs for multiple refilling
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing

Abstract

The invention includes a device having a chamber within a syringe. A fluid passageway extends through a syringe piston. A valve is associated with the passageway controlling fluid passage through the piston. The invention includes a piercing structure having a head segment and a body portion, with a channel through the body portion and through at least one surface of the head without passing through the tip. In another aspect the invention encompasses a method of preparing an agent for administration to an individual. A first component is provided within a syringe and a second component is provided within a vial. A closed valve is associated with a fluid passageway between the vial and the syringe barrel through a piston. Valve repositioning allows fluid passage and sliding of the piston joins the first and second components. Repeated sliding of the piston mixes the components to produce the medication agent.

Claims

1. A method of preparing a composition, comprising:

providing a packaging material containing a mixing device, the mixing device comprising;

a housing having a chamber therein, the chamber having a first length and containing a first material;

a piston slideable within the chamber, the piston having a second length that is greater than the first length;

a container having a second material therein, the container having a septum;

a fluid passageway disposed longitudinally through the piston;

a piercing structure associated with the piston, the piercing structure having a base portion, a head portion and a tube portion extending between the base portion and the head portion; and

a valve associated with the piston and orthogonally traversing the fluid passageway controlling fluid passage through the passageway;

without exposing the device to an environment external to the packaging material, puncturing the septum of the container with the piercing structure, the piercing structure being configured such that the tube portion traverses the septum and the head portion is retained within the container after the puncturing;

without exposing the device to an environment external to the packaging material, repositioning the valve from a closed position to an open position;

with the valve in the open position, sliding the piston in a first direction from a first position within the chamber to a second position within the chamber, the sliding drawing one of the first and second components through the piston;

mixing the first and second materials to form a mixture, the mixing comprising after sliding the piston in the first direction and with the valve in the open position, sliding the piston in a second direction opposite the first direction, and subsequently sliding the piston again in the first direction; and

drawing the mixture into the chamber through the piston.

2. The method of claim 1 wherein the mixing is performed without exposing the mixing device to the external environment.

3. The method of claim 1 wherein the composition is a medication agent and wherein the container is a medical vial.

4. The method of claim 1 wherein the housing is a syringe housing.

5. The method of claim 1 wherein the housing is a syringe housing, wherein the container is a medical vial, and further comprising:

after drawing the mixture into the chamber, returning the valve to the closed position; and

filtering the mixture.