System and method for detection of brain edema using spectrophotometry
First Claim
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1. A method of detecting or monitoring brain edema in a patient, comprising:
- emitting a first light into the patient'"'"'s brain tissue at a first wavelength through a partial bone region of the patient'"'"'s skull, wherein the partial bone region of the patient'"'"'s skull is approximately 3 cm behind a coronal suture of the patient'"'"'s skull, wherein the coronal suture includes a suture between parietal and frontal bones of the patient'"'"'s skull;
emitting a second light into the patient'"'"'s brain tissue at a second wavelength through said partial bone region;
detecting the first and second lights after dispersion by the brain tissue at a detector; and
determining an amount of water proximate the brain tissue based on the detected first and second lights.
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Abstract
Embodiments of the present invention relate to a system and method of detecting or monitoring brain edema in a patient. One embodiment of the present invention includes emitting a first light into the patient'"'"'s brain tissue at a first wavelength, emitting a second light into the patient'"'"'s brain tissue at a second wavelength, detecting the first and second lights after dispersion by the brain tissue at a detector, and determining an amount of water proximate the brain tissue based on the detected first and second lights.
153 Citations
16 Claims
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1. A method of detecting or monitoring brain edema in a patient, comprising:
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emitting a first light into the patient'"'"'s brain tissue at a first wavelength through a partial bone region of the patient'"'"'s skull, wherein the partial bone region of the patient'"'"'s skull is approximately 3 cm behind a coronal suture of the patient'"'"'s skull, wherein the coronal suture includes a suture between parietal and frontal bones of the patient'"'"'s skull; emitting a second light into the patient'"'"'s brain tissue at a second wavelength through said partial bone region; detecting the first and second lights after dispersion by the brain tissue at a detector; and determining an amount of water proximate the brain tissue based on the detected first and second lights. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of detecting or monitoring brain edema in a patient, comprising:
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emitting a first light into the patient'"'"'s brain tissue at a first wavelength approximately 1-5 mm away from a detector, wherein the first wavelength is within a 2100-2300 nm spectral region and wherein the first light is emitted through a partial bone region of the patient'"'"'s skull approximately 3 cm behind a coronal suture of the patient'"'"'s skull, wherein the coronal suture includes a suture between parietal and frontal bones of the patient'"'"'s skull; emitting a second light into the patient'"'"'s brain tissue at a second wavelength approximately 1-5 mm away from the detector, wherein the second wavelength is within the 1500-2300 nm spectral region and wherein the second light is emitted through said partial bone region; detecting the first and second lights after dispersion by the brain tissue at the detector; and determining an amount of water proximate the brain tissue based on the detected first and second lights. - View Dependent Claims (14, 15)
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16. A method of detecting or monitoring brain edema in a patient, comprising:
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emitting a first light into the patient'"'"'s brain tissue at a first wavelength approximately 10-30 mm away from a detector through a partial bone region of the patient'"'"'s skull approximately 3 cm behind a coronal suture of the patient'"'"'s skull, wherein the coronal suture includes a suture between parietal and frontal bones of the patient'"'"'s skull, and wherein the first wavelength is within a 1050-1350 nm spectral region; emitting a second light into the patient'"'"'s brain tissue at a second wavelength approximately 10-30 mm away from the detector through said partial bone region, wherein the second wavelength is within the 1050-1350 nm spectral region; detecting the first and second lights after dispersion by the brain tissue at the detector; and determining an amount of water proximate the brain tissue based on the detected first and second lights.
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Specification