Genes useful for diagnosing and monitoring inflammation related disorders
First Claim
1. A method for determining the likelihood of a human patient to reject a cardiac transplant comprising detecting the level of a RNA that encodes SEQ ID NO:
- 24 in a blood sample from said patient and determining that said patient is likely to reject said cardiac transplant when the level of said RNA that encodes SEQ ID NO;
24 is increased relative to the mean level of said RNA that encodes SEQ ID NO;
24 in quiescent samples.
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Abstract
Described herein is a system for monitoring gene expression for diagnosing and monitoring inflammation disorders, and for monitoring gene expression in inflammation disorders in response to a particular drug treatment regimen. This system for detecting nucleic acid expression in a body fluid uses an isolated polynucleotide to detect expression of a nucleic acid comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 5; SEQ ID NO:11; SEQ ID NO:17; and SEQ ID NO: 23. These nucleic acids are differentially expressed in body fluid in an individual with a disease criterion for a disease as listed in Table 1 as compared to an individual without the disease criterion.
185 Citations
6 Claims
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1. A method for determining the likelihood of a human patient to reject a cardiac transplant comprising detecting the level of a RNA that encodes SEQ ID NO:
- 24 in a blood sample from said patient and determining that said patient is likely to reject said cardiac transplant when the level of said RNA that encodes SEQ ID NO;
24 is increased relative to the mean level of said RNA that encodes SEQ ID NO;
24 in quiescent samples. - View Dependent Claims (2, 3, 4, 5, 6)
- 24 in a blood sample from said patient and determining that said patient is likely to reject said cardiac transplant when the level of said RNA that encodes SEQ ID NO;
Specification