Spatially variant image deformation
First Claim
Patent Images
1. An image registration system comprising:
- a deformation engine comprising;
first logic configured to compute a flexibility model comprising a first set of spatially variant constraints or spatially variant scalars and to apply the computed flexibility model to a medical deformable image to generate a set of displacement vectors, the set of displacement vectors being configured to apply a first force to the medical deformable image;
second logic configured to compute a non-Gaussian smoothing function and to apply the computed non-Gaussian smoothing function to the set of displacement vectors to create a smoothed set of displacement vectors;
third logic configured to compute a transform, the transform being configured to apply a second force to the medical deformable image, the second force opposing the first force; and
fourth logic configured to apply the smoothed set of displacement vectors and the transform to the medical deformable image to deform the medical deformable image to match a reference image.
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Abstract
Disclosed are systems for and methods of registering (i.e., aligning) a deformable image with a reference image subject to a spatially variant flexibility model and/or a non-Gaussian smoothing model. These systems and methods allow for the consideration of differences between the ways in which structures of interest may move within a patient. The registration includes modifying the deformable image to match similar features in the reference image. The systems include a deformation engine configured for performing a deformation algorithm subject to the spatially variant flexibility and/or smoothing models.
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Citations
27 Claims
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1. An image registration system comprising:
a deformation engine comprising; first logic configured to compute a flexibility model comprising a first set of spatially variant constraints or spatially variant scalars and to apply the computed flexibility model to a medical deformable image to generate a set of displacement vectors, the set of displacement vectors being configured to apply a first force to the medical deformable image; second logic configured to compute a non-Gaussian smoothing function and to apply the computed non-Gaussian smoothing function to the set of displacement vectors to create a smoothed set of displacement vectors; third logic configured to compute a transform, the transform being configured to apply a second force to the medical deformable image, the second force opposing the first force; and fourth logic configured to apply the smoothed set of displacement vectors and the transform to the medical deformable image to deform the medical deformable image to match a reference image. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. An image registration system comprising:
a deformation engine comprising; first logic configured to compute a flexibility model comprising a set of spatially variant constraints or spatially variant scalars and to apply the computed flexibility model to a medical deformable image to generate a set of displacement vectors, the set of displacement vectors being configured to apply a first force to the medical deformable image; second logic configured to compute a Gaussian smoothing function and to apply the computed Gaussian smoothing function to the set of displacement vectors to create a smoothed set of displacement vectors; third logic configured to compute a transform, the transform being configured to apply a second force to the medical deformable image, the second force opposing the first force; and fourth logic configured to apply the smoothed set of displacement vectors and the transform to the medical deformable image to deform the medical deformable image to match a reference image. - View Dependent Claims (10)
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11. An image registration system comprising:
a deformation engine comprising; first logic configured to compute a flexibility model and to apply the computed flexibility model to a medical deformable image to generate a set of displacement vectors, the set of displacement vectors being configured to apply a first force to the medical deformable image; second logic configured to compute a spatially variant smoothing function and to apply the computed spatially variant smoothing function to the set of displacement vectors to create a smoothed set of displacement vectors; third logic configured to compute a transform, the transform being configured to apply a second force to the medical deformable image, the second force opposing the first force; and fourth logic configured to apply the set of displacement vectors and the transform to the medical deformable image to deforming the medical deformable image to match a reference image. - View Dependent Claims (12, 13, 14)
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15. A method comprising:
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computing a set of displacement vectors according to a flexibility model comprising a first set of spatially variant constraints or spatially variant scalars, the set of displacement vectors being configured to apply a first force to a medical deformable image; applying a non-Gaussian smoothing function to the set of displacement vectors to create a smoothed set of displacement vectors; computing a transform configured to apply a second force to the medical deformable image, the second force opposing the first force; and applying the transform and the smoothed set of displacement vectors to the medical deformable image to match the medical deformable image to a reference image. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22)
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23. A method comprising:
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computing a set of displacement vectors according to a flexibility model comprising a set of spatially variant constraints or spatially variant scalars, the set of displacement vectors being configured to apply a first force to a medical deformable image; applying a Gaussian smoothing function to the set of displacement vectors to create a smoothed set of displacement vectors; computing a transform configured to apply a second force to the medical deformable image, the second force opposing the first force; and applying the computed transform and the smoothed set of displacement vectors to the medical deformable image to match the medical deformable image to a reference image. - View Dependent Claims (24)
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25. A method comprising:
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computing a set of displacement vectors according to a flexibility model and applying the set of displacement vectors to a medical deformable image, the set of displacement vectors being configured to apply a first force to the medical deformable image; applying a spatially variant smoothing function to the medical deformable image; computing a transform configured to apply a second force to the medical deformable image, the second force opposing the first force; and applying the transform to the medical deformable image to match the medical deformable image to a reference image. - View Dependent Claims (26, 27)
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Specification