Combining measurements from different sensors

• US 7,647,185 B2
• Filed: 06/08/2001
• Issued: 01/12/2010
• Est. Priority Date: 06/16/2000
• Status: Expired due to Fees

• Current Assignee: Oxford University Innovation Limited (University of Oxford)
• Original Assignee: Oxford Biosignals (Us) Incorporated
• Inventors: Townsend, Neil William, Price, James David, Tarassenko, Lionel
• Primary Examiner(s): Lin; Jerry
• Application Number:
  US10/311,250
• Publication Number:
  US 20030187337A1
• Time in Patent Office: 3,140 Days
• Field of Search: 702/19, 600/300
• US Class Current: 702/19
• CPC Class Codes: A61B 5/0245 by using sensing means generating electric signals, i.e. ECG signals
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts
• CPC Class Codes: G06F 18/256 of results relating to different input data, e.g. multimodal recognition

Abstract

A method for combining measurements from two or more independent measurement channels, particularly physiological measurements such as heart rate. Independent measurements of heart rate, for instance by ECG and pulse oximetry, can be combined to derive an improved measurement eliminating artefacts on one channel. A model of the process generating the physiological parameter, e.g., the heart rate, is constructed and is run independently for each channel to generate predictions of the parameter. The measured values are compared with the predicted values and the differences are used as an indication of the confidence in the measurement. The measurements from the two channels are ombined using weights calculated from the respective differences.

Claims

1. A method of measuring a parameter comprising using a suitably programmed computer to perform steps including:

predicting a value of each of two independent measurements of the parameter for two independent measurement channels, making two independent measurements of the parameter via said two independent measurement channels to produce two measured values of the parameter, calculating respective differences between the predicted values and the measured values for each of said two independent measurement channels, combining the two measured values with weights which vary inversely with said respective differences to produce a combined value, and outputting the combined value to a user.

2. A method according to claim 1 in which the predicting, the making of two independent measurements, the calculating and the combining are repeated, the predicted value for each of the two independent measurements being based on a preceding predicted value and a difference between the preceding predicted value and a preceding measured value.

3. A method according to claim 2 in which the predicted value for each of the two independent measurements is calculated by using a linear predictive model for each of said two independent measurement channels.

4. A method according to claim 2 in which the predicted value for each of the two independent measurements is calculated by using a non-linear predictive model for each of said two independent measurement channels.

5. A method according to claim 3 in which each model is adaptive, and it adapts in dependence upon the amount of process noise in the respective measurement channels.

6. A method according to claim 1 in which in the step of combining the two measured values the weights are inversely proportional to the squares of said respective differences.

8. A method according to claim 1 in which the predicted values for the respective measurements are based on respective models for measurement of said parameter via said two independent measurement channels.

9. A method according to claim 8 in which the models include estimates for process noise and sensor noise for said two independent measurement channels.

10. A method according to claim 8 in which the respective models are mutually independent.

11. A method according to claim 10 in which the respective models include the same estimates for process noise and sensor noise.

13. A method according to claim 1 further comprising discarding series of measurements for which the differences between both measured values and their predicted values exceed a predetermined threshold for a predetermined period of time.

14. A method according to claim 1 in which the parameter is heart rate.

15. A method according to claim 14 in which the two independent measurements are made from an electrocardiograph and a pulse oximetry waveform respectively constituting said two independent measurement channels.

16. A method according to claim 14 in which the two measurements are made from a multiple lead ECG recording.

17. A method according to claim 1 in which there are more than two measurements.

18. A method according to claim 1 further comprising identifying movement artifacts based on the values of the differences between both measured values and their predicted values.

19. A computer program encoded on a computer-readable storage medium and comprising program code which, when executed, performs the method of claim 1.

20. Apparatus configured to perform the method of claim 1.

21. A method according to claim 4 in which each model is adaptive, and it adapts in dependence upon the amount of process noise in the respective measurement channels.

7. A method of measuring a parameter comprising using a suitably programmed computer to perform steps including:

predicting a value of each of two independent measurements of the parameter for two independent measurement channels, making two independent measurements of the parameter via said two independent measurement channels to produce two measured values of the parameter, calculating respective differences between the predicted values and the measured values for each of said two independent measurement channels, combining the two measured values with weights determined by said respective differences to produce a combined value M, and outputting the combined value to a user, wherein the two measured values are combined according to the formula;

—

12. A method of measuring a parameter comprising using a suitably programmed computer to perform steps including:

predicting a value of each of two independent measurements of the parameter for two independent measurement channels using respective models for measurement of the parameter, making two independent measurements of the parameter via said two independent measurement channels to produce two measured values of the parameter, calculating respective differences between the predicted values and the measured values for each of said two independent measurement channels, combining the two measured values with weights which vary inversely with said respective differences to produce a combined value, and outputting the combined value to a user, wherein the respective models comprise Kalman filters.

22. A method of measuring a physiological parameter comprising using a suitably programmed computer to perform steps including:

predicting by use of respective Kalman filters a value of each of two independent measurements of the physiological parameter for two independent measurement channels, making two independent measurements of the physiological parameter via the two independent measurement channels to produce two measured values of the physiological parameter, calculating respective differences between the predicted values and the measured values for each of the two independent measurement channels, combining the two measured values with weights which vary inversely with which vary inversely with the respective differences to produce a physiological parameter measurement, and outputting the physiological parameter measurement to a user.

23. The method according to claim 22, in which the physiological parameter is heart rate.

24. The method according to claim 22, in which a first of the two measurement channels corresponds to an electrocardiograph and a second of the two measurement channels corresponds to pulse oximetry.

25. A computer-readable storage medium on which computer-executable instructions for performing the method according to claim 22 are encoded.

26. A method of measuring a parameter comprising using a suitably programmed computer to perform steps including:

predicting a value of each of two independent measurements of the parameter for two independent measurement channels;

making two independent measurements of the parameter via said two independent measurement channels to produce two measured current values of the parameter;

calculating respective differences between the predicted values and the measured current values for each of said two independent measurement channels; and

combining the two measured current values with weights which vary inversely with said respective differences to produce and output to a user a measurement of the parameter which is based on the two measured current values.

27. A method of measuring a parameter comprising using a suitably programmed computer to perform steps including:

predicting a value of each of two independent measurements of the parameter for two independent measurement channels;

making two independent measurements of the parameter via said two independent measurement channels to produce two measured current values of the parameter;

calculating respective differences between the predicted values and the measured current values for each of said two independent measurement channels;

combining the two measured current values with weights which vary inversely with said respective differences to produce a measurement of the parameter which is based on the two measured current values; and

displaying the measurement of the parameter.

28. A method according to claim 27 wherein the measurement of the parameter is displayed as part of a plot.

29. A computer-readable storage medium on which computer-executable instructions for performing the method according to claim 27 are encoded.