Diagnosis and treatment of human dormancy syndrome
First Claim
1. A method for treating a patient, comprising:
- (a) measuring serum levels of rT3 and fT3;
(b) calculating the ratio of rT3/fT3, wherein said ratio is above about 4; and
(c) determining the presence of one or more findings of human dormancy syndrome (HDS) selected from the group consisting of autoimmune disease, systemic lupus erythematosus, rheumatoid arthritis, post-Lyme disease, myositis, psoriatic arthritis, decreased mitochondrial membrane permeability, scleroderma, reflex sympathetic dystrophy, dementia and post-traumatic stress disorder; and
(d) administering T3 to decrease the ratio of serum rT3/fT3 to below about 4 and said finding returns substantially to normal.
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Abstract
New methods for diagnosis of human dormancy syndrome are provided. Human dormancy syndrome is characterized by elevated serum ratio of rT3/fT3 compared to a population of normal subjects from which subjects suffering from fibromyalgia, chronic fatigue, obesity, dementias including Alzheimer'"'"'s Disease and related dormancy conditions are excluded, and the presence of one or more findings related to reduced activity including torpor, chronic fatigue, insulin resistance, dementias, obesity and the like. Treatment of human dormancy syndrome is directed toward increasing fT3 levels or decreasing rT3 levels, or both, using pharmaceutical and/or behavioral methods. Other conditions that are associated with HDS can also be treated using T3 therapy, with or without specific psychological, behavioral or pharmaceutical therapies.
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Citations
11 Claims
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1. A method for treating a patient, comprising:
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(a) measuring serum levels of rT3 and fT3; (b) calculating the ratio of rT3/fT3, wherein said ratio is above about 4; and (c) determining the presence of one or more findings of human dormancy syndrome (HDS) selected from the group consisting of autoimmune disease, systemic lupus erythematosus, rheumatoid arthritis, post-Lyme disease, myositis, psoriatic arthritis, decreased mitochondrial membrane permeability, scleroderma, reflex sympathetic dystrophy, dementia and post-traumatic stress disorder; and (d) administering T3 to decrease the ratio of serum rT3/fT3 to below about 4 and said finding returns substantially to normal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification