Electroporation ablation apparatus, system, and method
First Claim
1. An ablation device, comprising:
- an elongate flexible member having a proximal end and a distal end and comprising;
a first working channel formed within the flexible member;
a first diagnostic probe having a proximal end and a distal end, the first diagnostic probe located within the first working channel and extending through the distal end of the flexible member; and
a first electrode connected to the distal end of the first diagnostic probe;
wherein the first electrode is adapted to be endoscopically located in a tissue treatment region; and
wherein the first electrode is adapted to couple to an electrical waveform generator to receive an irreversible electroporation electrical waveform sufficient to ablate tissue located proximate to the first electrode;
a second working channel formed within the flexible member;
a second diagnostic probe having a proximal end and a distal end, the second diagnostic probe located within the second working channel and extending through the distal end of the flexible member; and
a second electrode connected to the distal end of the second diagnostic probe;
wherein the second electrode is adapted to be endoscopically located in a tissue treatment region;
wherein the second electrode is adapted to couple to an electrical waveform generator to receive an irreversible electroporation electrical waveform sufficient to ablate tissue located between the first and second electrodes; and
wherein the first and second electrodes are rotatable about a central axis defined through each of the first and second diagnostic probes, wherein a distance between the first and second electrodes is adjustable by rotating either one or both of the first and second diagnostic probes.
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Accused Products
Abstract
A surgical instrument, such as an endoscopic or laparoscopic instrument, includes an ablation device. The ablation device includes an elongate flexible member having a proximal end and a distal end. A first working channel is formed within the flexible member. A first diagnostic probe having a proximal end and distal end is located within the first working channel and extends through the distal end of the flexible member. A first electrode is connected to the distal end of the first diagnostic probe electrode is adapted to be endoscopically located in a tissue treatment region. The first electrode is adapted to couple to an electrical waveform generator to receive an irreversible electroporation electrical waveform sufficient to ablate tissue located proximate to the first electrode. A system further includes an electrical waveform generator electrically coupled to the first electrode of the ablation device to generate an IRE waveform sufficient to ablate tissue located proximate to the first electrode.
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Citations
12 Claims
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1. An ablation device, comprising:
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an elongate flexible member having a proximal end and a distal end and comprising; a first working channel formed within the flexible member; a first diagnostic probe having a proximal end and a distal end, the first diagnostic probe located within the first working channel and extending through the distal end of the flexible member; and a first electrode connected to the distal end of the first diagnostic probe; wherein the first electrode is adapted to be endoscopically located in a tissue treatment region; and wherein the first electrode is adapted to couple to an electrical waveform generator to receive an irreversible electroporation electrical waveform sufficient to ablate tissue located proximate to the first electrode; a second working channel formed within the flexible member; a second diagnostic probe having a proximal end and a distal end, the second diagnostic probe located within the second working channel and extending through the distal end of the flexible member; and a second electrode connected to the distal end of the second diagnostic probe; wherein the second electrode is adapted to be endoscopically located in a tissue treatment region; wherein the second electrode is adapted to couple to an electrical waveform generator to receive an irreversible electroporation electrical waveform sufficient to ablate tissue located between the first and second electrodes; and wherein the first and second electrodes are rotatable about a central axis defined through each of the first and second diagnostic probes, wherein a distance between the first and second electrodes is adjustable by rotating either one or both of the first and second diagnostic probes. - View Dependent Claims (2, 3, 4)
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5. An ablation system, comprising:
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an ablation device comprising; an elongate flexible member having a proximal end and a distal end and comprising; a first working channel formed within the flexible member; a first diagnostic probe having a proximal end and a distal end, the first diagnostic probe located within the first working channel and extending through the distal end of the flexible member; and a first electrode connected to the distal end of the first diagnostic probe; wherein the first electrode is adapted to be endoscopically located in a tissue treatment region; and wherein the first electrode is adapted to receive an irreversible electroporation electrical (IRE) waveform sufficient to ablate tissue located proximate to the first electrode; a second working channel formed within the flexible member; a second diagnostic probe having a proximal end and a distal end, the second diagnostic probe located within the second working channel and extending through the distal end of the flexible member; and a second electrode connected to the distal end of the second diagnostic probe; wherein the second electrode is adapted to be endoscopically located in a tissue treatment region; wherein the second electrode is adapted to couple to an electrical waveform generator to receive an IRE waveform sufficient to ablate tissue located between the first and second electrodes; and wherein the first and second electrodes are rotatable about a central axis defined through each of the first and second diagnostic probes to adjust a distance between the first and second electrodes by rotating either one or both of the first and second diagnostic probes; and an electrical waveform generator electrically coupled to the first and second electrodes of the ablation device to generate an IRE waveform sufficient to ablate tissue located proximate to the first and second electrodes. - View Dependent Claims (6, 7, 8, 9, 10, 11, 12)
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Specification