Endovenous device for dispersing a dilating agent

• US 7,657,323 B2
• Filed: 07/25/2005
• Issued: 02/02/2010
• Est. Priority Date: 10/29/2001
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Kramm, Berthold, Doernberger, Volker
• Primary Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US11/189,053
• Publication Number:
  US 20050256559A1
• Time in Patent Office: 1,653 Days
• Field of Search: 607/120, 607/122, 607126-128, 607/116, 607/119, 607/121, 600/585
• US Class Current: 607/120
• CPC Class Codes: A61M 2025/0057 Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
• CPC Class Codes: A61M 2025/0177 having external means for receiving guide wires, wires or stiffening members, e.g. loops, clamps or lateral tubes
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61N 1/0568 with drug delivery
• CPC Class Codes: A61N 2001/0585 Coronary sinus electrodes

Abstract

Apparatus and methods are disclosed for inserting electrical leads within a heart. A method is provided for positioning a medical electrical lead in a cardiac vein. The method comprises inserting a lead within a coronary sinus, dispersing at least one vasodilating agent to dilate at least one cardiac vein, and inserting the lead into a dilated cardiac vein.

Claims

1. A medical electrical lead device, comprising:

an elongated flexible lead body having a distal end portion and a proximal end portion, the lead body being adapted for insertion through a superior vena cava of a patient and passage through a coronary sinus of a patient to position the distal end within a cardiac vein adjacent to a left ventricle of a patient;

an electrode coupled to the distal end of the lead body;

means coupled to the distal end of the lead body for anchoring the electrode within the cardiac vein; and

means formed at the distal end portion of the lead body proximal to the electrode for dispersing a vasodilating agent within a vessel during insertion and passage of the lead body to position the distal end within the cardiac vein, wherein the vasodilating agent is delivered along the lead body to the means for dispersing from the proximal end, and wherein the means for dispersing includes a plurality of apertures formed in the lead body to disperse the vasodilating agent.

2. A medical electrical lead device as set forth in claim 1, wherein the lead is an over-the-wire lead.

3. A medical electrical lead device, as set forth in claim 1, wherein the elongated flexible body comprises a flexible tube, and the apertures are formed in the flexible tube.

4. A medical electrical lead device, as set forth in claim 1, wherein the elongated flexible body comprises a tube constructed with material selected from the group consisting of polyurethane and silicone.

5. A medical electrical lead device, as set forth in claim 1, wherein said lead is tapered along a longitudinal axis of the elongated flexible body.

6. A medical electrical lead device, as set forth in claim 1, wherein the lead comprises a core of electrically conductive material surrounded by a layer of insulative material.

7. A medical electrical lead device as set forth in claim 1, wherein the anchoring means comprises an expandable helical coil coupled to its distal end.

8. The medical electrical lead device of claim 1, further comprising a fluid source containing the vasodilating agent, wherein the source is coupled to provide the vasodilating agent to the dispersing means.

9. The medical electrical lead device of claim 1, further comprising:

a first lumen to accommodate a guide wire; and

a second lumen that receives the vasodilating agent at the proximal end of the second lumen and delivers the vasodilating agent along the lead body to the means for dispersing,

wherein the second lumen defines the plurality of apertures.

10. The medical electrical lead device of claim 1, further comprising a lumen to accommodate a guide wire, receive the vasodilating agent at the proximal end of the lumen, and deliver the vasodilating agent along the lead body to the means for dispersing in an annulus area between the guide wire and the lumen, wherein the lumen defines the plurality of apertures.

11. The medical electrical lead device of claim 1, wherein the plurality of apertures are formed at different positions along a length of the elongated flexible lead body, and some of the apertures are configured to disperse different quantities of the vasodilating agent.

12. A medical catheter device, comprising:

a flexible tubular body having a distal end and a proximal end;

a first lumen disposed within the flexible tubular body capable of transporting an electrical lead through the first lumen and out the distal end of the flexible tubular body to an implant site within a cardiac vein adjacent to a left ventricle of a patient;

means for dispersing a vasodilating agent within a vessel during insertion and passage of the tubular body to position the distal end within the cardiac vein, wherein the means for dispersing a vasodilating agent is attached near the distal end of the tubular body and comprises a sponge-like material, wherein the vasodilating agent is selectively delivered from the proximal end to the means for dispersing; and

a fluid source containing the vasodilating agent, wherein the source is coupled to provide the vasodilating agent to the dispersing means.

13. The medical catheter device of claim 12, wherein the sponge-like material is capable of being saturated or impregnated with the vasodilating agent.

14. A medical catheter device, comprising:

a flexible tubular body having a distal end and a proximal end;

a first lumen disposed within the flexible tubular body capable of transporting an electrical lead through the first lumen and out the distal end of the flexible tubular body to an implant site within a cardiac vein adjacent to a left ventricle of a patient;

means for dispersing a vasodilating agent within a vessel during insertion and passage of the tubular body to position the distal end within the cardiac vein, wherein the means for dispersing a vasodilating agent is attached near the distal end of the tubular body and the vasodilating agent is selectively delivered from the proximal end to the means for dispersing;

a second lumen for transporting the vasodilating agent from the proximal end to the distal end of the tubular body; and

a fluid source containing the vasodilating agent, wherein the source is coupled to provide the vasodilating agent to the second lumen.