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Apparatus and methods for delivery of transcranial magnetic stimulation

  • US 7,658,704 B2
  • Filed: 10/29/2004
  • Issued: 02/09/2010
  • Est. Priority Date: 05/04/2001
  • Status: Active Grant
First Claim
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1. A method of transcranial magnetic stimulation, comprising:

  • defining a cerebral cortical region of interest for a subject;

    determining a stimulator position and orientation disposed to deliver an induced electric field substantially perpendicular to said cerebral cortical region of interest in accordance with a cortical column cosine aiming principle such that the electric field is parallel to cortical columns of the cerebral cortical region of interest;

    positioning said subject to immobilize said cerebral cortical region of interest;

    directing said stimulator to said subject so that said stimulator is focused to said cerebral cortical region of interest, said directing based on said determined stimulator position and orientation; and

    delivering said TMS to said subject, said delivering comprising generating an electric field substantially perpendicular to said cerebral cortical region of interest.

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