Method and apparatus to sense temperature in an implantable pump

• US 7,658,737 B2
• Filed: 09/10/2001
• Issued: 02/09/2010
• Est. Priority Date: 04/30/1999
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Olsen, James M., Hartlaub, Jerome T.
• Primary Examiner(s): DeSanto; Matthew F
• Application Number:
  US09/950,154
• Publication Number:
  US 20020042596A1
• Time in Patent Office: 3,074 Days
• Field of Search: 604/93.01, 604/500, 604/503, 604/95.01, 604/131, 604/288.04, 6048901-8902, 604/891.1, 604/892.1, 374/100, 374/141, 600/300, 705/2, 417/32, 417/63, 702/130, 702/132, 702/179, 702/182
• US Class Current: 604/891.1
• CPC Class Codes: A61M 2005/14264 with means for compensating influence from the environment
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/3372 Temperature compensation
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/50 Temperature
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: F04B 13/00 Pumps specially modified to deliver fixed or variable measured quantities
• CPC Class Codes: F04B 2201/0403 Carter housing temperature

Abstract

An implantable drug infusion pump for delivering drug therapy is made more reliable and its performance improved by monitoring drug pump temperature. Monitoring pump temperature can also provide for temperature-related drug therapy modification.

A pump temperature sensor is read by the infusion pump'"'"'s microprocessor. Pump temperature data is stored in pump memory for later access by a remote controller. A simple thermistor or semiconductor temperature sensor can provide fast and reliable temperature monitoring of the pump and/or of a patient by reading the temperature sensor'"'"'s value and calculating a temperature therefrom.

Claims

1. An automatic drug therapy delivery system, capable of detecting the possibility of damage to the pump prior to implant, the system comprising:

a) an implantable pump;

b) a temperature sensor producing electrically measurable signals that are indicative of the temperature of the implantable pump over time prior to implantation; and

c) a controller having at least one input that receives the signals from the temperature sensor, wherein the controller monitors the signals from the temperature sensor prior to implantation of the implantable pump and stores those signals from the temperature sensor that are indicative of the implantable pump being exposed to a temperature that is one or more of inside or outside of a pre-determined normal range at which the implantable pump can be safely stored.

2. The automatic drug delivery system of claim 1, wherein the controller comprises a microprocessor.

3. The automatic drug delivery system of claim 2, wherein the microprocessor further provides an indication regarding the suitability of implanting the implantable pump based on the signals received from the temperature sensor.

4. The automatic drug therapy delivery system of claim 3, wherein the indication provided by the microprocessor comprises an audio signal.

5. The automatic drug therapy delivery system of claim 3, wherein the indication provided by the microprocessor comprises a visual signal.

6. The automatic drug delivery system of claim 1, wherein the controller generates a temperature profile from the signals, the temperature profile being retrievable to detect a possible pump damaging temperature, and wherein the temperature profile comprises a histogram.

7. The automatic drug delivery system of claim 6, wherein the histogram comprises ranges of high temperature, normal temperature, and low temperature.

8. The automatic drug delivery system of claim 6, further comprising a data link coupled to the controller for the retrieval of the temperature profiles.

9. The automatic drug delivery system of claim 6, further comprising at least one storage device for storing the temperature profile.

10. The automatic drug delivery system of claim 6, further comprising a plurality of memory storage locations wherein the temperature profile of the implantable pump is stored.

11. The automatic drug therapy delivery system of claim 6, wherein the controller further generates the temperature profile that provides information about an accumulated time that the implantable pump was exposed to corresponding to the at least one abnormal temperature range.

12. The automatic drug therapy delivery system of claim 6, further comprising:

a pump reservoir that connects to the implantable pump and that contains a medicament, the medicament being temperature sensitive; and

wherein the controller generates the temperature profile that is retrievable to detect a possible medicament damaging temperature.

13. The automatic drug delivery system of claim 1, further comprising a clock, operatively coupled to the controller, the clock generating an output signal representative of time and date.

14. The automatic drug delivery system of claim 1, wherein the at least one abnormal temperature range is below the normal temperature range.

15. The automatic drug delivery system of claim 1, wherein the controller is configured to provide an indication of the amount of time that the implantable pump was exposed to a temperature outside of the normal temperature range.

16. An automatic drug therapy delivery system, capable of detecting the possibility of damage to the pump prior to implant, the system comprising:

a) an implantable pump;

b) a temperature sensor producing electrically measurable signals that are indicative of temperature to which the implantable pump is subjected prior to implantation; and

c) a controller having at least one input that receives the signals from the temperature sensor, the controller monitoring and recording the signals from the temperature sensor prior to implantation, the controller further including a discriminator to separate the received signals into categories representing one of three pre-determined temperature ranges, the three temperature ranges comprising a below normal temperature range, a normal temperature range and an above normal temperature range.

17. The automatic drug delivery system of claim 16, wherein the controller is configured to make the determination of which temperature range the signal corresponds to while the implantable pump is not in operation.

18. The automatic drug delivery system of claim 16, wherein the controller is configured to make the determination of which temperature range the signal corresponds to prior to the implantable pump being implanted within a patient.

19. The automatic drug delivery system of claim 16, wherein the controller is a microprocessor.