Intralumenally implantable frames

• US 7,658,759 B2
• Filed: 07/17/2006
• Issued: 02/09/2010
• Est. Priority Date: 04/24/2003
• Status: Active Grant

• Current Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Original Assignee: Cook Incorporated (Cook Group Incorporated)
• Inventors: Case, Brian C., Flagle, Jacob A., Garrison, Michael L.
• Primary Examiner(s): Stewart; Alvin J
• Application Number:
  US11/487,629
• Publication Number:
  US 20070021826A1
• Time in Patent Office: 1,303 Days
• Field of Search: 623 115- 118, 623/1.24, 623/1.26, 623/2.12, 623/2.14, 623/2.18
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2475 Venous valves
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0054 V-shaped

Abstract

Implantable frames for use in body passages are provided herein. The implantable frames comprise one or more of certain preferred structural features that are generally applicable to frames comprising a plurality of curved and straight member portions that together define an interior lumen extending along a longitudinal axis between a proximal end and a distal end. The implantable frames have an exterior surface comprising a plurality of openings between the interior lumen and the exterior surface, and preferably include one or more undulating hoop members attached to one or more longitudinal connecting members. The implantable frames can be formed from any suitable material, but preferably comprise material permitting the frame to radially self-expand from a radially compressed configuration to a radially expanded configuration. The implantable frames are useful for endolumenal implantation within a body vessel, for example as a stent or as a support frame of an implantable valve.

Claims

1. An implantable frame defining a substantially cylindrical lumen extending between a proximal end and a distal end along a longitudinal axis, the implantable frame having an exterior surface area with a plurality of openings, the implantable frame moveable between a compressed configuration and an expanded configuration, the implantable frame comprising:

a proximal undulating hoop member having a plurality of struts and bends, a distal undulating hoop member having a plurality of struts and bends, and a plurality of longitudinal connecting members connecting the proximal undulating hoop member to the distal undulating hoop member;

where the implantable frame comprises only two of the undulating hoop members, each of the proximal undulating hoop member and the distal undulating hoop member comprising a closed hoop structure formed by only four struts connected to each other by one or more bends;

where each longitudinal connecting member is connected to at least one bend of the proximal undulating hoop member and at least one bend of the distal undulating hoop member, the implantable frame comprising at least four of the longitudinal connecting members;

where each of the four struts is connected to the one or more bends adjacent to at least one of the longitudinal connecting members; and

where the ratio between the length of the implantable frame and the length of the longitudinal connecting members is about 1.50 to about 2.00, the length of the implantable frame measured from the inflection point of the most distal bend in the distal hoop member and the inflection point of the most proximal bend in the proximal hoop member.

2. The implantable frame of claim 1, wherein the ratio is between about 1.65 and 1.75.

3. The implantable frame of claim 1, where the longitudinal connecting members have substantially equal length, and where the implantable frame comprises at least one closely-spaced pair of circumferentially adjacent longitudinal connecting members, where the distance between the closely paired longitudinal connecting members is less than about 25% of the length of the pair of longitudinal connecting members.

4. The implantable frame of claim 1, where the proximal undulating hoop member comprises a first strut and a second strut connected by a single bend, and further comprising a proximal bridging member connecting the first strut and the second strut.

5. The implantable frame of claim 1, wherein the implantable frame is self-expanding.

6. The implantable frame of claim 1, wherein the implantable frame in the expanded configuration is characterized by two or more symmetry planes containing the longitudinal axis of the implantable frame.

7. The implantable frame of claim 1, where the implantable frame comprises a plurality of substantially parallel longitudinal connecting members each having a substantially equal length and each extending between a proximal hoop member and a distal hoop member, including a first longitudinal connecting member circumferentially adjacent to a second longitudinal connecting member, the second longitudinal connecting member positioned between the first longitudinal connecting member and a third longitudinal connecting member, wherein

a. the circumferential distance between the first longitudinal connecting member and the second longitudinal connecting member is less than about 25% of the length of the longitudinal connecting members;

and

b. the circumferential distance between the first longitudinal connecting member and the third longitudinal connecting member is greater than 25% of the length of the longitudinal connecting members.

8. The implantable frame of claim 1, where the proximal hoop member comprises a first strut, the plurality of longitudinal connecting members have a substantially equal length and include a first longitudinal connecting member extending between the proximal hoop member and the distal hoop member, and the proximal undulating hoop member comprises a first bend having a semi-circular configuration extending between the first longitudinal connecting member and the first strut, the first bend subtending an arc having a radius centered on the distal side of the proximal hoop member, where each longitudinal connecting member is substantially parallel to the longitudinal axis, and the first bend subtends an angle of between about 135°

and about 175°

between the first longitudinal connecting member and the first strut segment.

9. The implantable frame of claim 1, where the longitudinal connecting members have substantially equal length, and where the implantable frame comprises four closely-spaced pairs of circumferentially adjacent longitudinal connecting members, where one end of each pair of circumferentially adjacent longitudinal connecting members is connected to a single bend connecting two of the four struts of one of the undulating hoop members together and the other end of each pair of circumferentially adjacent longitudinal connecting members is connected to three bends connecting two of the four struts of the other undulating hoop member together, one of the three bends connecting the pair of circumferentially adjacent longitudinal connecting members together, and the other two of the three bends connecting one of the struts to one of the pair of circumferentially adjacent longitudinal connecting members, where each of the proximal undulating hoop member and the distal undulating hoop comprise two of the single bends and two of the three bends.

10. The implantable frame of claim 9, wherein the implantable frame is self-expanding.

11. The implantable frame of claim 10, where the distance between the closely paired longitudinal connecting members is less than about 25% of the length of the pair of longitudinal connecting members and the distance between adjacent pairs of longitudinal connecting members is greater than about 25% of the length of the pair of longitudinal connecting members.

12. The implantable frame of claim 11, wherein the ratio between the length of the implantable frame and the length of the longitudinal connecting members is about 1.65 and 1.75.

13. The implantable frame of claim 12, further comprising a proximal bridging member connecting each of the struts which are connected together with a single bend.

14. The implantable frame of claim 13, where the proximal hoop member comprises a first strut, the plurality of longitudinal connecting members have a substantially equal length and include a first longitudinal connecting member extending between the proximal hoop member and the distal hoop member, and the proximal undulating hoop member comprises a first bend having a semi-circular configuration extending between the first longitudinal connecting member and the first strut, the first bend subtending an arc having a radius centered on the distal side of the proximal hoop member, where each longitudinal connecting member is substantially parallel to the longitudinal axis, and the first bend subtends an angle of between about 135°

and about 175°

between the first longitudinal connecting member and the first strut segment.

15. The implantable frame of claim 14, wherein the implantable frame in the expanded configuration is characterized by two or more symmetry planes containing the longitudinal axis of the implantable frame.

16. The implantable frame of claim 1, where the longitudinal connecting members have substantially equal length;

and where the implantable frame comprises only four longitudinal connecting members, where one end of each longitudinal connecting member is connected to a single bend connecting two of the four struts of one of the undulating hoop members together and the other end of each longitudinal connecting member is connected to two bends connecting two of the four struts of the other undulating hoop member together, each of the two bends connecting one of the struts to the longitudinal connecting member, where each of the proximal undulating hoop member and the distal undulating hoop comprise two of the single bends and two of the two bends.

17. The implantable frame of claim 16, wherein the implantable frame is self-expanding.

18. The implantable frame of claim 17, wherein the ratio between the length of the implantable frame and the length of the longitudinal connecting members is about 1.65 and 1.75.

19. The implantable frame of claim 18, further comprising a proximal bridging member connecting each of the struts which are connected together with a single bend.