Systems and methods for determining respiration metrics

• US 7,662,105 B2
• Filed: 12/14/2005
• Issued: 02/16/2010
• Est. Priority Date: 12/14/2005
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Hatlestad, John
• Primary Examiner(s): Mallari; Patricia C
• Application Number:
  US11/300,675
• Publication Number:
  US 20070135725A1
• Time in Patent Office: 1,525 Days
• Field of Search: 600/529
• US Class Current: 600/529
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/0809 by impedance pneumography
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance

Abstract

Systems, devices and methods provide for acquiring respiration information. A respiration information device includes timer circuitry to time a plurality of shorter time apertures and a plurality of longer time apertures. A respiration sensor, which may be implemented as a transthoracic impedance sensor, is configured to generate a signal indicative of patient respiration. For each aperture of the plurality of shorter time apertures and for each aperture of the plurality of longer time apertures, an estimated characteristic of the respiration is determined. Respiration metrics are developed using one or both of the estimated respiration characteristics of the shorter time apertures and the estimated respiration characteristics of the longer time apertures.

Claims

1. A respiration information device, comprising:

timer circuitry configured to time a plurality of shorter time apertures and a plurality of longer time apertures;

a respiration sensor configured to generate a signal indicative of patient respiration; and

respiration information circuitry configured to determine, for each aperture of the plurality of shorter time apertures and for each aperture of the plurality of longer time apertures, an estimated value of a respiration characteristic based on the respiration, the respiration information circuitry comprising;

measurement circuitry configured to measure the respiration characteristic for each breath cycle of each aperture; and

a respiration processor configured to determine the estimated value of the respiration characteristic for each aperture based on the measurement of the respiration characteristic and configured to determine a maximum respiration value from the estimated values determined for the plurality of shorter time apertures and to determine a minimum respiration value from the estimated values determined for the plurality of longer time apertures.

2. The device of claim 1, wherein the respiration information circuitry is configured to determine one or more respiration metrics using one or both of the estimated values of the respiration characteristic determined for the shorter time apertures and the estimated values of the respiration characteristic determined for the longer time apertures.

3. The device of claim 1, wherein at least one of the timer circuitry, the respiration sensor, and the respiration information circuitry includes an implantable component.

4. The device of claim 1, wherein the respiration sensor comprises a transthoracic impedance sensor.

5. The device of claim 1, wherein the respiration characteristic is a respiration rate.

6. The device of claim 2, further comprising a trending unit configured to develop a trend using at least one of the estimated values of the respiration characteristic determined for the plurality of shorter time apertures, the estimated values of the respiration characteristic determined for the plurality of longer time apertures, and the one or more respiration metrics.

7. The device of claim 2, further comprising a diagnostics unit configured to detect a presence of a disease or disorder using at least one of the estimated values of the respiration characteristic determined for the plurality of shorter time apertures, the estimated values of the respiration characteristic determined for the plurality of longer time apertures, and the one or more respiration metrics.

8. The device of claim 7, wherein the disease or disorder comprises heart failure.

9. The device of claim 1, further comprising a therapy unit configured to deliver therapy based on a presence of a disease or disorder.

10. The device of claim 9, wherein the therapy comprises a pacing therapy.

14. The system of claim 1, wherein the respiration characteristic comprises a breath volume characteristic.

15. The system of claim 1, wherein the respiration characteristic comprises tidal volume.

16. The system of claim 1, wherein the estimated value comprises a median value.

17. The system of claim 1, wherein the estimated value comprises a mean value.

18. The system of claim 1, wherein the estimated value comprises a daily value.

19. The system of claim 1, wherein the estimated value comprises a maximum value or a minimum value.

11. A medical system, comprising:

timer circuitry configured to time a plurality of shorter time apertures and a plurality of longer time apertures;

a respiration sensor configured to generate a signal indicative of patient respiration;

means for determining, for each aperture of a plurality of shorter time apertures and for each aperture of a plurality of longer time apertures, an estimated value of a characteristic of the respiration based on the respiration signal; and

means for determining one or more respiration metrics using one or both of the estimated values of the respiration characteristic of the plurality of shorter time apertures and the estimated values of the respiration characteristic of the plurality of longer time apertures; and

means for determining a maximum respiration value from the estimated values of the respiration characteristic determined for the plurality of shorter time aperture and for determining a minimum respiration value from the estimated values of the respiration characteristic determined for the plurality of longer time apertures;

wherein the respirator characteristic comprises respiration rate.

12. The system of claim 11, further comprising means for tracking progression of heart failure using at least one of the estimated values of the respiration characteristic determined for the plurality of shorter time apertures, the estimated values of the respiration characteristic determined for the plurality of longer time apertures, and the one or more respiration metrics.

13. The system of claim 12, further comprising means for initiating, modifying or terminating therapy based on the heart failure progression.