Method of preventing β cell disruption in pancreatic Langerhans' islets
First Claim
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1. A method for preventing β
- -cell disruption in pancreatic Langerhans'"'"' islets of a type II diabetes patient, which method comprisesadministering granulocyte colony-stimulating factor as an active ingredient of a composition to a type II diabetic patient in need thereof in an amount sufficient to provide said preventing.
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Abstract
The object of the present invention is to provide a method for treating diabetes which is simple, safe and effective when compared to conventional diabetes treatment. The administration of one or more stem cell-recruiting factors allows a simple and safe repair of disrupted β-cells in pancreatic Langerhans'"'"' islets. Thus, the therapeutic agent of the present invention which comprises one or more stem cell-recruiting factors as active ingredients is useful for diabetes treatment. Examples of such a stem cell-recruiting factor include colony-stimulating factors such as G-CSF.
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2 Claims
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1. A method for preventing β
- -cell disruption in pancreatic Langerhans'"'"' islets of a type II diabetes patient, which method comprises
administering granulocyte colony-stimulating factor as an active ingredient of a composition to a type II diabetic patient in need thereof in an amount sufficient to provide said preventing. - View Dependent Claims (2)
- -cell disruption in pancreatic Langerhans'"'"' islets of a type II diabetes patient, which method comprises
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Current AssigneeChugai Seiyaku Kabushiki Kaisha (Roche Holding AG)
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Original AssigneeChugai Seiyaku Kabushiki Kaisha (Roche Holding AG)
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InventorsKawabe, Yoshiki, Adachi, Yuichiro
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Primary Examiner(s)Spector; Lorraine
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Assistant Examiner(s)STOICA, ELLY GERALD
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Application NumberUS10/553,672Publication NumberTime in Patent Office2,133 DaysField of SearchNoneUS Class Current424/85.1CPC Class CodesA61K 38/193 Colony stimulating factors ...A61P 1/18 for pancreatic disorders, e...A61P 3/10 for hyperglycaemia, e.g. an...A61P 43/00 Drugs for specific purposes...
